KEGG   Aquifex aeolicus: aq_1812
Entry
aq_1812           CDS       T00013                                 
Symbol
thrA
Name
(RefSeq) homoserine dehydrogenase
  KO
K00003  homoserine dehydrogenase [EC:1.1.1.3]
Organism
aae  Aquifex aeolicus
Pathway
aae00260  Glycine, serine and threonine metabolism
aae00270  Cysteine and methionine metabolism
aae00300  Lysine biosynthesis
aae01100  Metabolic pathways
aae01110  Biosynthesis of secondary metabolites
aae01120  Microbial metabolism in diverse environments
aae01230  Biosynthesis of amino acids
Module
aae_M00018  Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:aae00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    aq_1812 (thrA)
   00270 Cysteine and methionine metabolism
    aq_1812 (thrA)
   00300 Lysine biosynthesis
    aq_1812 (thrA)
Enzymes [BR:aae01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.3  homoserine dehydrogenase
     aq_1812 (thrA)
SSDB
Motif
Pfam: Homoserine_dh NAD_binding_3 ACT GFO_IDH_MocA Sacchrp_dh_NADP F420_oxidored NAD_Gly3P_dh_N Glyco_trans_1_4 ACT_4 ACT_7 ADH_zinc_N_2 ACT_6
Other DBs
NCBI-GeneID: 1193484
NCBI-ProteinID: NP_214243
UniProt: O67677
Position
1277001..1278308
AA seq 435 aa
MGFVRVGIIGCGTVGTGTAKLLIQNADLIKKKTGIEFKLVKVADIDWERKREFEVPKELR
TTDYKEVIDNSDVVVELVGGKTFAKKVILEALEAGKCVVTANKHLLAEEGKEIFEEAKKR
NLFIGFEASVGGGIPVIKALREGLAGNKILNILGILNGTTNYILTRMFEENLDFETALKE
AKEKGYAEADPSLDIDGWDAAHKIAILAMLAYGGYLDFNDVYVEGIRNVDKLDVELGKEL
GYTLKLLAIAKKVDSEVEVRVHPTFIHSEEALAKVSGVYNAVMIEGDFVGKTMFYGQGAG
SHPTASAVVADVIDAGRFLLCSSKVLPPVNWEEGELKVRKNFYSRYYLRFDVPDKPGVLA
KIANVLADYNISIASVLQKEMVCKIAGREGETIVPLVILTHKAFEEDIQNALKEIQKLPV
VVDKPVLIRVEEEAY
NT seq 1308 nt   +upstreamnt  +downstreamnt
atgggctttgtaagggtcggaataatcggttgcggtacggttggaacgggaaccgccaaa
ctcctcatacagaatgcagacctaataaagaagaaaacgggtatagagttcaaactcgtg
aaagttgcggacatagactgggagagaaagagggagtttgaagttccgaaagaactgaga
accacagattataaagaagttatagataattcggacgtggtcgttgaactcgtaggcggt
aaaactttcgctaagaaggtaatactggaagctctggaagcgggaaagtgcgttgttaca
gcaaataaacacctcctcgcagaggaagggaaggagatttttgaagaggccaagaagaga
aacttatttataggttttgaagcctcggtgggaggagggattcccgtgataaaagcgtta
agggaaggacttgcggggaataaaattctcaacatcctcggtatcctcaacggaacgaca
aattacatactcacgaggatgtttgaggaaaatcttgactttgaaacggctttaaaggaa
gcaaaagaaaaagggtatgcggaggcagatccaagtcttgacatagacgggtgggatgcg
gctcacaagattgctattctcgccatgctcgcctacggtgggtatctagactttaacgac
gtttacgtagagggtataaggaacgttgataagctcgacgtagaactgggaaaggaactg
ggatacacactgaaactcctcgcaatcgcgaaaaaagttgactcggaggttgaggtgagg
gttcatcccacctttatacactccgaggaagcccttgcaaaggtctccggagtttacaac
gcagtcatgatagagggagattttgtagggaaaaccatgttctatggtcagggggcgggt
tcacatccgaccgcttctgcggtggtggcggacgtgatagacgcggggaggttcttactc
tgtagctctaaggttcttcctcccgtgaactgggaagaaggagaactgaaggtcaggaag
aacttttactccaggtactaccttaggtttgacgttcctgacaagcccggagttctggca
aagatagcgaatgtacttgcggattacaatataagcatagcctcggttctccagaaggaa
atggtttgtaaaatcgcgggcagggagggtgaaactatagttcctctggttatcctgact
cacaaagcttttgaagaggatatacagaacgctttaaaggagatacagaagctccccgta
gttgttgataagcccgtgctgatacgtgtggaagaggaggcttactga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (9)   
   KEGG PATHWAY (7)   
   KEGG MODULE (2)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   RefGene (20)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (12)   
   Pfam (12)   
All databases (59)   

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