KEGG   Canis lupus familiaris (dog): 100686778
Entry
100686778         CDS       T01007                                 
Symbol
CYP1A1
Name
(RefSeq) cytochrome P450 1A1
  KO
K07408  cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa00140  Steroid hormone biosynthesis
cfa00380  Tryptophan metabolism
cfa00830  Retinol metabolism
cfa00980  Metabolism of xenobiotics by cytochrome P450
cfa01100  Metabolic pathways
cfa04913  Ovarian steroidogenesis
cfa05204  Chemical carcinogenesis - DNA adducts
cfa05207  Chemical carcinogenesis - receptor activation
cfa05208  Chemical carcinogenesis - reactive oxygen species
cfa05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    100686778 (CYP1A1)
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    100686778 (CYP1A1)
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    100686778 (CYP1A1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    100686778 (CYP1A1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    100686778 (CYP1A1)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    100686778 (CYP1A1)
   05207 Chemical carcinogenesis - receptor activation
    100686778 (CYP1A1)
   05208 Chemical carcinogenesis - reactive oxygen species
    100686778 (CYP1A1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100686778 (CYP1A1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:cfa00199]
    100686778 (CYP1A1)
Enzymes [BR:cfa01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     100686778 (CYP1A1)
Cytochrome P450 [BR:cfa00199]
 Cytochrome P450, animal type
  CYP1 family
   100686778 (CYP1A1)
SSDB
Motif
Pfam: p450 Gemini_BL1
Other DBs
NCBI-GeneID: 100686778
NCBI-ProteinID: XP_003433938
Ensembl: ENSCAFG00000017937
VGNC: 50332
UniProt: A0A0U2PTV9
Position
30:complement(37726194..37732463)
AA seq 524 aa
MMSMFRLSIPISASELLLASTVFCLVLWVVKAWQPRLPKGLKSPPGPWGWPLLGNVLTLG
KSPHLALSRLSQRYGDVLQIRIGSTPVLVLSGLDTIRQALVRQGDDFKGRPDLYSFSLVT
DGQSLTFSPDSGPVWAARRRLAQNALKSFSIASDPASSCSCYLEEHVSKEAEVLLSRLQE
QMAEVGRFDPYRYIVVSVANVICAMCFSKRYDHDDQELLSLVNLSNEFGEGVASANPLDF
FPILRYLPNPALDFFKDLNKRFYSFMQKMVKEHYKTFEKGQIRDVTDSLIEHCQDKRLDE
NANIQLSDEKIVNVVLDLFGAGFDTVTTAISWSLLYLVTNPNVQKKIQKELDTVIGRARQ
PRLSDRPQLPYMEAFILETFRHASFVPFTIPHSTTRDTSLSGFYIPKGRCVFVNQWQINH
DQKLWGNPSEFQPERFLTLDGTINKALSEKVILFGLGKRKCIGETIARLEVFLFLAILLQ
QVEFSVPEGTKVDMTPIYGLTMKHARCEHFQVRVRTEGAESPAA
NT seq 1575 nt   +upstreamnt  +downstreamnt
atgatgtccatgttcagactctccatccccatctcggcctcagagcttctcctggcctcc
accgtcttctgcttggtactctgggtggtcaaggcctggcagcctcggcttcccaaaggc
ctgaagagtccaccggggccctggggctggcccctgctcgggaacgtgctgaccttgggc
aagagcccccacctggcgctgtccaggctgagccagcgttatggggacgtgctgcagatc
cgcatcggctccacccccgtgctggtgctcagtggcctggacaccatccggcaggccctg
gtgcgccagggggatgatttcaagggccggcccgacctctacagcttctctctggttacc
gacggccaaagcctgaccttcagcccagactccggaccagtgtgggctgcgcgcaggcgc
ctggcccagaacgcgctgaagagtttctccattgcctccgacccggcttcctcgtgctct
tgctacctggaagagcatgtgagcaaggaggccgaggtccttctcagcaggctgcaggag
cagatggcagaggttgggcgctttgatccctatagatacatagtggtgtcggtggccaac
gtcatctgtgccatgtgctttagcaagcgctatgaccatgacgaccaggagctgcttagc
ttagtcaacctgagtaatgagtttggagagggggttgcctctgcgaaccccttggacttc
tttcccatccttcgatacctacccaaccctgccctggatttcttcaaggacctgaataag
agattctacagcttcatgcaaaagatggtcaaggaacactataaaacgtttgagaagggc
caaattcgggatgtcacagacagcctgatcgagcactgtcaggataagaggctggatgag
aatgccaatatccagctgtctgatgagaagattgttaatgttgtcttggacctctttgga
gctggatttgacacagtcacaactgccatctcctggagcctcctgtacttggtgacaaac
cccaatgtacagaaaaagatccagaaggagctggacacagtgattggcagggcacggcaa
ccccggctctctgacaggccccagctgccctacatggaggcattcatcctggagaccttc
cgacatgcttccttcgtccccttcaccatccctcatagcaccacaagagacacgagtctg
agtggcttttacatccccaagggacgttgcgtctttgtgaaccagtggcagatcaaccat
gaccagaagctatggggtaacccgtctgagttccaaccagaacgattcctcactctcgat
ggcaccatcaacaaggcactgagtgagaaggtgattctctttggtttgggcaagcggaag
tgcatcggtgagaccatcgctcgcttggaggtctttctctttctggccatcctgctgcag
caggtggaatttagtgtgccagagggcacaaaggtagatatgacccccatttatgggctg
accatgaagcacgcccgctgtgaacacttccaagtgagggtgcgcactgagggggctgag
agccctgcagcctag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (10)   
   KEGG PATHWAY (10)   
Chemical substance (43)   
   KEGG COMPOUND (43)   
Chemical reaction (22)   
   KEGG ENZYME (1)   
   KEGG REACTION (21)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (6)   
   UniProt (1)   
   RefSeq(pep) (5)   
DNA sequence (9)   
   RefSeq(nuc) (5)   
   GenBank (2)   
   EMBL (2)   
Protein domain (2)   
   Pfam (2)   
All databases (108)   

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