KEGG   Canis lupus familiaris (dog): 100855560
Entry
100855560         CDS       T01007                                 
Symbol
DDX58
Name
(RefSeq) antiviral innate immune response receptor RIG-I isoform X5
  KO
K12646  ATP-dependent RNA helicase DDX58 [EC:5.6.2.6]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04064  NF-kappa B signaling pathway
cfa04622  RIG-I-like receptor signaling pathway
cfa04623  Cytosolic DNA-sensing pathway
cfa05160  Hepatitis C
cfa05161  Hepatitis B
cfa05162  Measles
cfa05164  Influenza A
cfa05168  Herpes simplex virus 1 infection
cfa05169  Epstein-Barr virus infection
cfa05171  Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    100855560 (DDX58)
 09150 Organismal Systems
  09151 Immune system
   04622 RIG-I-like receptor signaling pathway
    100855560 (DDX58)
   04623 Cytosolic DNA-sensing pathway
    100855560 (DDX58)
 09160 Human Diseases
  09172 Infectious disease: viral
   05161 Hepatitis B
    100855560 (DDX58)
   05160 Hepatitis C
    100855560 (DDX58)
   05171 Coronavirus disease - COVID-19
    100855560 (DDX58)
   05164 Influenza A
    100855560 (DDX58)
   05162 Measles
    100855560 (DDX58)
   05168 Herpes simplex virus 1 infection
    100855560 (DDX58)
   05169 Epstein-Barr virus infection
    100855560 (DDX58)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04054 Pattern recognition receptors [BR:cfa04054]
    100855560 (DDX58)
Enzymes [BR:cfa01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.6  RNA 3'-5' helicase
     100855560 (DDX58)
Pattern recognition receptors [BR:cfa04054]
 Cytoplasmic pattern recognition receptors
  RIG-I-like receptors
   100855560 (DDX58)
SSDB
Motif
Pfam: CARD_2 RIG-I_C RIG-I_C-RD DEAD ResIII Helicase_C AAA_22 CCDC85 AAA_25 PhoH
Other DBs
NCBI-GeneID: 100855560
NCBI-ProteinID: XP_005626758
Ensembl: ENSCAFG00000001807
VGNC: 39867
UniProt: A0A8C0QM78
Position
11:complement(48386814..48422172)
AA seq 925 aa
MTAEERRNLHAFRDYVIKTLDPAYILSYMAPWFKDDEVQYIQAEKNNKGTMEAASLFLKC
LLELQEEGWFRGFLDALGHAGYSGLYEAIESWNFQKIESLEEYRLLLKRLQPEFKTTVNP
NDILPKISECLISQECEEIIQICSNKGLMAGAEKMVECLLRSDKENWPKTLKLALETEES
KFSQLWIVDKDVELKVLEDEEIETSEVQIFYKEEPECQNLSQDPCPPSVASTCTPLKPRN
YQLELALPAKEGKNTIICAPTGCGKTFVALLICEHHLKKFPQGQKGKIVFFAIQIPVYEQ
QNSVFSKYFERLGYKVAGISGATSENISVEQIVENNDIIVLTPQILVNCLRNGTIPSLSV
FTLMIFDECHNTSKHHPYNMIMFNYLDQKLGGSSDPLPQVVGLTASVGIGDAKNTMEAME
YICKLCASLDTSVIATVKDNLEELEEIVYKPQKFFRKVESRTTDRFKCIISQLMRETESL
AKNIFDELGTITLENVSQIQNRNFGTQKYEQWIVSVQKACMVFQLPNKDEESRICKALFL
YTSHLRKYNDALIINEHARMKDALDYLKDFFTDVRAAGFDEIEQHLTYRFEEKLQELESI
SMDLSNENPKLKDLSFILQEEYHLNPESRTILFVKTRALVDALKKWIEENSELSFLKPGI
LTGRGKTNHNTGMTLPAQKCALDAFRTDGDKKILIATSVADEGIDIAQCNLVILYEYVGN
VIRMIQTRGRGRARGSKCFLLTSNADVIKKEKLNIYKEKIMNDSILSLQMWNEAVFKEKV
LQIQIQEKNIRDSQEKVELVPDKENKKLLCRKCKAFACYTADIRVVEECHYTVVGDAFTK
CFVSKLHPKPKSFGHFEKRAKIFCARRNCGHDWGIHVKYKTFEIPVIKIESFVVEDIATG
AQKLYAKWKDFPFEKIPFGSPEIPE
NT seq 2778 nt   +upstreamnt  +downstreamnt
atgacggccgaggagcggcgaaacctgcacgccttccgggactatgtcatcaagactctg
gaccctgcctacatcctgagctacatggccccctggtttaaggatgatgaggtgcagtat
attcaggctgagaagaacaataaaggcacgatggaggctgcctcactttttcttaagtgc
ctattggagctccaagaagaaggctggttccgtggctttttggatgcccttggtcatgca
ggttattctggactttatgaagcaattgaaagttggaatttccaaaaaattgaaagtcta
gaggagtatagattgcttttaaagcgtttacaaccagaatttaaaactacagttaatcca
aatgatattcttcctaaaatatctgaatgtttaattagtcaggaatgtgaagaaattata
cagatttgttccaacaaggggctgatggcaggtgcggagaaaatggttgaatgccttctc
agatcagacaaagaaaactggcccaaaactttgaaacttgctttggagacagaagagagc
aagttcagtcaactgtggattgtggacaaagatgttgaactgaaagttcttgaggatgaa
gaaatagaaacttccgaagtacagattttctataaggaagaaccagaatgccagaatctt
agtcaggacccatgtccaccttcagtggcttctacttgcaccccactgaagccaagaaat
taccaactagaacttgctttgcctgctaaggaaggaaaaaatacaataatatgtgctcct
actggttgtggaaaaacctttgttgcccttcttatatgtgaacatcatcttaaaaaattt
ccccaaggacaaaaggggaagattgtcttttttgctattcaaatcccagtgtatgaacag
cagaattctgtgttctccaaatattttgaaagacttgggtacaaagttgcaggtatttct
ggagcaacatctgagaatatctcagtggaacagatcgttgagaacaatgacatcatcgtt
ttaactccacagattcttgtgaattgccttagaaatgggactattccatcactctctgtc
tttactttgatgatatttgatgaatgtcacaacaccagtaaacaccatccttacaatatg
atcatgtttaattatctagatcagaaacttggaggatcttcagacccactgcctcaggtt
gttgggctgactgcctcagttggcatcggggatgccaaaaacacaatggaagccatggaa
tatatctgcaaactgtgtgcttctcttgacacatcagtgatagcaacagtcaaagacaac
ttggaggaattggaagaaattgtttataagccccagaagtttttcaggaaagtggaatca
cggactactgacagatttaaatgcatcatttctcagctgatgagggagacagagagtctg
gcaaagaatatctttgatgaactcggtaccataactctcgaaaatgtatctcaaattcaa
aataggaattttggaacacagaaatatgaacaatggatcgtttctgttcagaaggcatgc
atggtgtttcagttacccaacaaagatgaagagagcaggatttgtaaagcactgtttttg
tacacttcccacttgcggaaatataatgatgccctcattatcaatgagcatgcacgaatg
aaagatgctctggattacttgaaagacttcttcactgatgtccgagcagcaggatttgat
gagattgagcagcatctcacttatagattcgaagaaaagctgcaggaactggaaagtatt
tccatggatctcagcaatgagaaccctaaactcaaagatctctccttcatcttgcaagag
gagtaccacttaaacccagagagtagaactatcctctttgtgaaaaccagagcacttgtg
gatgctttgaagaaatggattgaagaaaattctgaactcagcttcctaaaacctggcata
ttgactggacgtggcaaaacaaatcacaatacaggaatgacactcccagcgcagaagtgt
gcattggatgcattcagaactgatggagataaaaagattctgattgccacctcagttgct
gatgaaggcatcgacattgctcagtgcaatttggtcatcctgtatgagtacgtgggcaat
gtcatcagaatgatccaaaccagaggcagaggaagagcaagaggtagcaagtgcttcctt
ctaactagcaatgctgatgtaattaaaaaagaaaaactaaacatatacaaagaaaaaata
atgaatgactccattttaagccttcagatgtggaatgaagcagtatttaaagaaaaggtt
ctccagatacagattcaagaaaaaaacatcagagatagtcaagaaaaagtagaacttgta
cctgataaggaaaataaaaaactgctctgcagaaagtgcaaagcctttgcatgttataca
gctgacatcagagtggtggaggaatgccattacactgtggttggagatgcattcacgaag
tgcttcgtgagtaagttacaccctaaaccaaagagctttgggcattttgagaagagagca
aagatcttctgtgccagacggaactgtggccatgactggggaatccatgtgaagtataag
acatttgagattccagttatcaaaatagaaagctttgtggtggaagatattgcgaccgga
gctcagaaactatatgcaaagtggaaggactttccttttgagaagataccctttggttct
ccagaaatacccgaatga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (10)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (16)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (6)   
   UniProt (1)   
   RefSeq(pep) (5)   
DNA sequence (7)   
   RefSeq(nuc) (5)   
   GenBank (1)   
   EMBL (1)   
Protein domain (10)   
   Pfam (10)   
All databases (59)   

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