KEGG   Canis lupus familiaris (dog): 100856539
Entry
100856539         CDS       T01007                                 
Symbol
F2
Name
(RefSeq) prothrombin
  KO
K01313  coagulation factor II (thrombin) [EC:3.4.21.5]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04072  Phospholipase D signaling pathway
cfa04080  Neuroactive ligand-receptor interaction
cfa04610  Complement and coagulation cascades
cfa04611  Platelet activation
cfa04810  Regulation of actin cytoskeleton
cfa05171  Coronavirus disease - COVID-19
cfa05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    100856539 (F2)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    100856539 (F2)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100856539 (F2)
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    100856539 (F2)
   04611 Platelet activation
    100856539 (F2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100856539 (F2)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    100856539 (F2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:cfa01002]
    100856539 (F2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:cfa04147]
    100856539 (F2)
   00536 Glycosaminoglycan binding proteins [BR:cfa00536]
    100856539 (F2)
Enzymes [BR:cfa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.5  thrombin
     100856539 (F2)
Peptidases and inhibitors [BR:cfa01002]
 Serine peptidases
  Family S1: chymotrypsin family
   100856539 (F2)
Exosome [BR:cfa04147]
 Exosomal proteins
  Exosomal proteins of hepatic cells
   100856539 (F2)
Glycosaminoglycan binding proteins [BR:cfa00536]
 Heparan sulfate / Heparin
  Coagulation and fibrinolysis
   100856539 (F2)
SSDB
Motif
Pfam: Trypsin Kringle Thrombin_light Gla DUF1986 Trypsin_2
Other DBs
NCBI-GeneID: 100856539
NCBI-ProteinID: XP_003639742
Ensembl: ENSCAFG00000009122
VGNC: 40547
UniProt: A0A8C0PX10 A0A8I3PUT1
Position
18:complement(41511662..41528485)
AA seq 621 aa
MAHIRGLWLPGCLVILFSLAHSQHVFLDPQQALSLLHRVRRANSGFLEELRKGNLERECV
EEQCNYEEAFEALESSTATDVFWSKYTACEPVRKPREKLVECLEGSCAEGLGMNYRGNVS
FTRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDGSTTGPWCYTIDPTVRREEC
SISLCGQQGGVTVPLTPRSGGPTVNLSPPSEHCIPERGRYYQGRLAVTTHGSPCLAWASR
QAKALSKDQDFNPAVPLVENFCRNPDGDEEGAWCYVSEEPGGFEYCDLDYCEEPVEEVGD
GLAEDQDTAIEGRTTAEEFQPFFNEKTFGAGEADCGLRPLFEKRSVKDKTEGELLESYID
GRIVEGWDAEIGLAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEND
LLVRIGKHSRTRYERSIEKISMLEKIYIHPRYNWRENLDRDIALLKLKKPVNFSNYIHPV
CLPDRDTATRLLQAGYKGRVTGWGNLRETWTSSIGEVQPRVLQVVNLPIVDRQVCKASTR
IRITDNMFCAGYKPNEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYG
FYTHVFRLKKWIQKVIEKSGG
NT seq 1866 nt   +upstreamnt  +downstreamnt
atggcgcacatccgaggcctgtggttacctggctgcctcgtcatcctctttagccttgcg
cacagccagcatgtgttcctggaccctcagcaagcactatcactgctccaccgggtccga
cgtgccaacagtggcttcctggaggagctgcgcaaggggaacctggagcgagagtgtgtg
gaggagcagtgcaactacgaggaggcctttgaggccctggagtcttctactgccacggat
gtgttctggtccaaatacacagcttgtgagccggtgaggaaacctcgagaaaagctcgtt
gaatgtctggaaggtagctgtgctgaaggtctgggtatgaattaccgagggaacgtgagc
ttcacccggtcaggcatcgagtgccagttatggaggagtcgctacccacataagcctgaa
atcaactctaccacccaccctggggccgacctgcaggagaatttctgccgtaacccggat
ggcagcaccactgggccctggtgctatactatagaccccaccgtgcggcgagaggagtgt
agcatctccctctgcggccagcagggaggcgtcactgtgccgctgaccccacgctccgga
ggccccacggtgaatctgtcacctccatcagagcactgcatccctgagcgtggccggtac
taccagggtcgcctggcggtgaccacacatgggtccccctgcctggcctgggccagcaga
caggccaaggccctgagcaaggaccaggacttcaaccctgcggtgccgctggtggagaac
ttctgccgcaacccggacggggacgaggagggcgcgtggtgttacgtgtcggaggagcca
ggtggctttgagtactgcgacctggactactgcgaggagcccgtggaggaggtgggcgac
gggctggccgaggaccaggacacggccatcgagggacgcaccaccgcagaggagttccag
cccttcttcaacgaaaagaccttcggcgccggggaggcagactgtgggctgcgacctttg
ttcgagaagaggtcggtgaaggacaaaacggaaggggagcttctggagtcctacatcgac
gggcgcatcgtggagggttgggacgcggagattggcctcgcgccctggcaggtgatgctt
ttccggaagagtccccaggagctgctgtgtggggccagcctcataagtgaccgctgggtt
ctcactgctgcccactgtctcctgtacccaccttgggacaaaaacttcacagagaatgac
cttctggtgcgcattggcaagcactcccgtaccaggtatgagcgaagcattgagaagatc
tccatgctggaaaagatctacatccaccccaggtacaactggagggaaaacttggaccgt
gacatagccttgctgaagctcaagaagcctgtcaacttcagcaactacatccaccccgtg
tgcctgcctgacagggatacagcaaccagactgctccaggctgggtacaaagggcgggtg
accggctggggcaacctgagggagacgtggacatccagcattggtgaagtacagcccaga
gtcctgcaggtggtgaacctgcccattgtggatcggcaggtctgcaaggcctccacccgg
atccgcatcactgacaacatgttctgtgctggttataaacccaatgaagggaaacgaggg
gatgcttgtgaaggcgacagtgggggaccatttgtcatgaagagcccctttaacaaccgc
tggtatcaaatgggcatcgtctcctggggtgaaggctgtgacagggatggaaaatatggc
ttctacacacatgtgttccgcctgaagaaatggatacagaaggtcattgagaagtctgga
ggttag

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Ontology (5)   
   KEGG BRITE (5)   
Pathway (7)   
   KEGG PATHWAY (7)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (38)   
   KEGG ORTHOLOGY (1)   
   RefGene (32)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (7)   
   UniProt (2)   
   RefSeq(pep) (5)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (6)   
   Pfam (6)   
All databases (70)   

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