KEGG   Canis lupus familiaris (dog): 399544
Entry
399544            CDS       T01007                                 
Symbol
VWF
Name
(RefSeq) von Willebrand factor precursor
  KO
K03900  von Willebrand factor
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04151  PI3K-Akt signaling pathway
cfa04510  Focal adhesion
cfa04512  ECM-receptor interaction
cfa04610  Complement and coagulation cascades
cfa04611  Platelet activation
cfa04613  Neutrophil extracellular trap formation
cfa05165  Human papillomavirus infection
cfa05171  Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    399544 (VWF)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    399544 (VWF)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    399544 (VWF)
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    399544 (VWF)
   04611 Platelet activation
    399544 (VWF)
   04613 Neutrophil extracellular trap formation
    399544 (VWF)
 09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    399544 (VWF)
   05165 Human papillomavirus infection
    399544 (VWF)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:cfa03110]
    399544 (VWF)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:cfa04147]
    399544 (VWF)
Chaperones and folding catalysts [BR:cfa03110]
 Intramolecular chaperones
  Others
   399544 (VWF)
Exosome [BR:cfa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   399544 (VWF)
SSDB
Motif
Pfam: VWD VWA C8 VWA_N2 TIL VWC Pacifastin_I MCR_beta_N
Other DBs
NCBI-GeneID: 399544
NCBI-ProteinID: NP_001002932
Ensembl: ENSCAFG00000015228
VGNC: 48329
UniProt: Q28295
Position
27:complement(7641828..7779174)
AA seq 2813 aa
MSPTRLVRVLLALALILPGKLCTKGTVGRSSMARCSLFGGDFINTFDESMYSFAGDCSYL
LAGDCQEHSVSLIGGFQNGKRVSLSVYLGEFFDIHLFVNGTMLQGTQSISMPYASNGLYL
EAEAGYYKLSSEAYGFVARIDGNGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFRTQEGTL
TSDPYDFANSWALSSGEQRCKRVSPPSSPCNVSSDEVQQVLWEQCQLLKSASVFARCHPL
VDPEPFVALCERTLCTCVQGMECPCGVLLEYARACAQQGVVLYGWTDHSVCRPACPAGME
YKECVSPCTRTCQSLHVKEVCQEQCVDGCSCPEGQLLDEGHCVGSAECSCVHAGQRYPPG
ASLLQDCHTCICRNSLWICSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLAQDCQD
HTFSVVIETVQCADDLDAVCTRSVTVRLPGHHNSLVKLKHGGGVSMDGQDIQIPLLQGDL
RIQHTVMASVRLSYGEDLQMDWDGRGRLLVTLSPAYAGKTCGLCGNYNGNRGDDFVTPAG
LAEPLVEDFGNAWKLLGACENLQKQHRDPCSLNPRQARFAEEACALLTSSKFEPCHRAVG
PQPYVQNCRYDVCSCSDGRDCLCSAVANYAAACARRGVHIAWREPGFCALSCPQGQVYLQ
CGTPCNMTCRSLSYPEEDCNEVCLEGCFCPPGLYLDERGDCVPKAQCPCYYDGEIFQPED
IFSDHHTMCYCEDGFMHCTTSGGLGSLLPNPVLSSPRSHRSKRSLSCRPPMVKLVCPADN
PRAEGLECAKTCQNYDLQCMSTGCVSGCLCPQGMVRHENRCVALERCPCFHQGQEYAPGE
TVKIDCNTCVCRDRKWNCTDHVCDATCSAIGMAHYLTFDGLKYLFPGECQYVLVQDYCGS
NPGTFRILVGNEGCSYPSVKCKKRVTILVEGGEIELFDGEVNVKKPMKDETHFEVVESGQ
YVILLLGKALSVVWDHRLSISVTLKRTYQEQVCGLCGNFDGIQNNDFTSSSLQIEEDPVD
LGNSWKVNPQCADTKKVPLDSSPAVCHNNIMKQTMVDSSCRILTSDIFQDCNRLVDPEPF
LDICIYDTCSCESIGDCTCFCDTIAAYAHVCAQHGKVVAWRTATFCPQNCEERNLHENGY
ECEWRYNSCAPACPITCQHPEPLACPVQCVEGCHAHCPPGKILDELLQTCIDPEDCPVCE
VAGRRLAPGKKIILNPSDPEHCQICHCDGVNFTCQACREPGSLVVPPTEGPIGSTTSYVE
DTPEPPLHDFHCSRLLDLVFLLDGSSKLSEDEFEVLKVFVVGMMEHLHISQKRIRVAVVE
YHDGSHAYIELKDRKRPSELRRITSQVKYAGSEVASTSEVLKYTLFQIFGKIDRPEASRI
ALLLMASQEPSRLARNLVRYVQGLKKKKVIVIPVGIGPHASLKQIHLIEKQAPENKAFVF
SGVDELEQRRDEIINYLCDLAPEAPAPTQHPPMAQVTVGSELLGVSSPGPKRNSMVLDVV
FVLEGSDKIGEANFNKSREFMEEVIQRMDVGQDRIHVTVLQYSYMVTVEYTFSEAQSKGE
VLQQVRDIRYRGGNRTNTGLALQYLSEHSFSVSQGDREQVPNLVYMVTGNPASDEIKRMP
GDIQVVPIGVGPHANVQELEKIGWPNAPILIHDFEMLPREAPDLVLQRCCSGEGLQIPTL
SPTPDCSQPLDVVLLLDGSSSIPASYFDEMKSFTKAFISRANIGPRLTQVSVLQYGSITT
IDVPWNVAYEKVHLLSLVDLMQQEGGPSQIGDALSFAVRYVTSEVHGARPGASKAVVILV
TDVSVDSVDAAAEAARSNRVTVFPIGIGDRYSEAQLSSLAGPKAGSNMVRLQRIEDLPTV
ATLGNSFFHKLCSGFDRVCVDEDGNEKRPGDVWTLPDQCHTVTCLPDGQTLLKSHRVNCD
RGPRPSCPNGQPPLRVEETCGCRWTCPCVCMGSSTRHIVTFDGQNFKLTGSCSYVLFQNK
EQDLEVILHNGACSPGAKETCMKSIEVKHDGLSVELHSDMQMTVNGRLVSIPYVGGDMEV
NVYGTIMYEVRFNHLGHIFTFTPQNNEFQLQLSPRTFASKTYGLCGICDENGANDFILRD
GTVTTDWKALIQEWTVQQLGKTCQPVPEEQCPVSSSSHCQVLLSELFAECHKVLAPATFY
AMCQPDSCHPKKVCEAIALYAHLCRTKGVCVDWRRANFCAMSCPPSLVYNHCEHGCPRLC
EGNTSSCGDQPSEGCFCPPNQVMLEGSCVPEEACTQCISEDGVRHQFLETWVPAHQPCQI
CTCLSGRKVNCTLQPCPTARAPTCGPCEVARLRQNAEQCCPEYECVCDLVSCDLPPVPPC
EDGLQMTLTNPGECRPNFTCACRKDECRRESPPSCPPHRTPALRKTQCCDEYECACNCVN
STVSCLLGYLASAVTNDCGCTTTTCFPDKVCVHRGTIYPVGQFWEEACDVCTCTDLEDSV
MGLRVAQCSQKPCEDNCLSGFTYVLHEGECCGRCLPSACEVVIGSPRGDAQSHWKNVGSH
WASPDNPCLINECVRVKEEVFVQQRNVSCPQLNVPTCPTGFQLSCKTSECCPTCHCEPLE
ACLLNGTIIGPGKSLMIDVCTTCRCTVQVGVISGFKLECRKTTCEACPLGYKEEKNQGEC
CGRCLPIACTIQLRGGQIMTLKRDETIQDGCDSHFCKVNERGEYIWEKRVTGCPPFDEHK
CLAEGGKIMKIPGTCCDTCEEPECKDIIAKLQRVKVGDCKSEEEVDIHYCEGKCASKAVY
SIHMEDVQDQCSCCSPTQTEPMQVPLRCTNGSLIYHEILNAMQCRCSPRKCSK
NT seq 8442 nt   +upstreamnt  +downstreamnt
atgagtcctaccagacttgtgagggtgctgctggctctggccctcatcttgccagggaaa
ctttgtacaaaagggactgttggaaggtcatcgatggcccgatgtagcctcttcggaggt
gacttcatcaacacctttgatgagagcatgtacagctttgcgggagattgcagttacctc
ctggctggggactgccaggaacactccgtctcacttatcgggggtttccaaaatggcaaa
agagtgagcctctccgtgtatctcggagaatttttcgacattcatttgtttgtcaatggt
accatgctgcaggggacccaaagcatctccatgccctacgcctccaatgggctgtatcta
gaggccgaggctggctactacaagctgtccagtgaggcctacggctttgtggccagaatt
gatggcaatggcaactttcaagtcctgctgtcagacagatacttcaacaagacctgtggg
ctgtgtggcaactttaatatctttgctgaggatgacttcaggactcaagaagggacgttg
acttcggacccctatgactttgccaactcctgggccctgagcagtggggaacaacggtgc
aaacgggtgtcccctcccagcagcccatgcaatgtctcctctgatgaagtgcagcaggtc
ctgtgggagcagtgccagctcctgaagagtgcctcggtgtttgcccgctgccacccgctg
gtggaccctgagccttttgtcgccctgtgtgaaaggactctgtgcacctgtgtccagggg
atggagtgcccttgtggggtcctcctggagtacgcccgggcctgtgcccagcagggggtt
gtcttgtacggctggaccgaccacagcgtctgccgaccagcatgccctgctggcatggag
tacaaggagtgcgtgtccccttgcaccagaacttgccagagccttcatgtcaaagaagtg
tgtcaggagcaatgtgtagatggctgcagctgccccgagggccagctcctggatgaaggc
cactgcgtgggaagtgctgagtgttcctgtgtgcatgctgggcaacggtaccctccgggc
gcctccctcttacaggactgccacacctgcatttgccgaaatagcctgtggatctgcagc
aatgaagaatgcccaggcgagtgtctggtcacaggacagtcccacttcaagagcttcgac
aacaggtacttcaccttcagtgggatctgccagtacctgctggcccaggactgccaggac
cacaccttctctgttgtcatagagactgtccagtgtgccgatgacctggatgctgtctgc
acccgctcggtcaccgtccgcctgcctggacatcacaacagccttgtgaagctgaagcat
gggggaggagtctccatggatggccaggatatccagattcctctcctgcaaggtgacctc
cgcatccagcacaccgtgatggcctccgtgcgcctcagctacggggaggacctgcagatg
gattgggacggccggggcaggctgctggtgacgctgtccccggcctacgcggggaagacg
tgcggcctgtgcgggaactacaacggcaaccggggggacgacttcgtgacgcccgcaggc
ctggcggagcccctggtggaggacttcgggaacgcctggaagctgctcggggcctgcgag
aacctgcagaagcagcaccgcgatccctgcagcctcaacccgcgccaggccaggtttgcg
gaggaggcgtgcgcgctgctgacgtcctcgaagttcgagccctgccaccgagcggtgggt
cctcagccctacgtgcagaactgccgctacgacgtctgctcctgctccgacggcagagac
tgtctttgcagcgccgtggccaactacgccgcagcctgtgcccggaggggcgtgcacatc
gcgtggcgggagcccggcttctgtgcgctgagctgcccccagggccaggtgtacctgcag
tgtgggaccccctgcaacatgacctgtcgctccctctcttacccggaggaggactgcaat
gaggtctgcttggaaggctgcttctgccccccagggctgtacctggatgagaggggagat
tgtgtgcccaaggctcagtgtccctgttactatgatggtgagatctttcagcccgaagac
atcttctcagaccatcacaccatgtgctactgtgaggatggcttcatgcactgtaccaca
agtggaggcctgggaagcctgctgcccaacccggtgctcagcagcccccggtctcaccgc
agcaaaaggagcctgtcctgtcggccccccatggtcaagttggtgtgtcccgctgataac
ccgagggctgaaggactggagtgtgccaaaacctgccagaactatgacctgcagtgcatg
agcacaggctgtgtctccggctgcctctgcccgcagggcatggtccggcatgaaaacagg
tgtgtggcgctggaaagatgtccctgcttccaccaaggccaagagtacgccccaggagaa
accgtgaaaattgactgcaacacttgtgtctgtcgggaccggaagtggaactgcacagac
catgtgtgtgatgccacttgctctgccatcggcatggcgcactacctcaccttcgacgga
ctcaagtacctgttccctggggagtgccagtatgttctggtgcaggattactgtggcagt
aaccctgggaccttccggatcctggtggggaacgaggggtgcagctacccctcagtgaaa
tgcaagaagcgggtcaccatcctggtggaaggaggagagattgaactgtttgatggggag
gtgaatgtgaagaaacccatgaaggatgagactcactttgaggtggtagagtctggtcag
tacgtcattctgctgctgggcaaggcactctctgtggtctgggaccaccgcctgagcatc
tctgtgaccctgaagcggacataccaggagcaggtgtgtggcctgtgtgggaattttgat
ggcatccagaacaatgatttcaccagcagcagcctccaaatagaagaagaccctgtggac
cttgggaattcctggaaagtgaacccgcagtgtgccgacaccaagaaagtaccactggac
tcctctcctgccgtctgccacaacaacatcatgaagcagacgatggtggattcctcctgc
aggatcctcaccagtgatattttccaggactgcaacaggctggtggaccctgagccattc
ctggacatttgcatctacgacacttgctcctgtgagtccattggggactgcacctgcttc
tgtgacaccattgctgcttacgcccatgtctgtgcccagcatggcaaggtggtagcctgg
aggacagccacattctgtccccagaattgcgaggagcggaatctccacgagaatgggtat
gagtgtgagtggcgctataacagctgtgcccctgcctgtcccatcacgtgccagcacccc
gagccactggcatgccctgtacagtgtgttgaaggttgccatgcgcactgccctccaggg
aaaatcctggatgagcttttgcagacctgcatcgaccctgaagactgtcctgtgtgtgag
gtggctggtcgtcgcttggccccaggaaagaaaatcatcttgaaccccagtgaccctgag
cactgccaaatttgtcattgtgatggtgtcaacttcacctgtcaggcctgcagagaaccc
ggaagtcttgtggtgccccccacagaaggccccattggctctaccacctcgtatgtggag
gacacgccggagccgcccctccatgacttccactgcagcaggcttctggacctggttttc
ctgctggatggctcctccaagctgtctgaggacgagtttgaagtgctgaaggtctttgtg
gtgggtatgatggagcatctgcacatctcccagaagcggatccgcgtggctgtggtggag
taccacgacggctcccacgcctacatcgagctcaaggaccggaagcgaccctcagagctg
cggcgcatcaccagccaggtgaagtacgcgggcagcgaggtggcctccaccagtgaggtc
ttaaagtacacgctgttccagatctttggcaagatcgaccgcccggaagcgtctcgcatt
gccctgctcctgatggccagccaggagccctcaaggctggcccggaatttggtccgctat
gtgcagggcctgaagaagaagaaagtcattgtcatccctgtgggcatcgggccccacgcc
agccttaagcagatccacctcatagagaagcaggcccctgagaacaaggcctttgtgttc
agtggtgtggatgagttggagcagcgaagggatgagattatcaactacctctgtgacctt
gcccccgaagcacctgcccctactcagcaccccccaatggcccaggtcacggtgggttcg
gagctgttgggggtttcatctccaggacccaaaaggaactccatggtcctggatgtggtg
tttgtcctggaagggtcagacaaaattggtgaggccaactttaacaaaagcagggagttc
atggaggaggtgattcagcggatggacgtgggccaggacaggatccacgtcacagtgctg
cagtactcgtacatggtgaccgtggagtacaccttcagcgaggcgcagtccaagggcgag
gtcctacagcaggtgcgggatatccgataccggggtggcaacaggaccaacactggactg
gccctgcaatacctgtccgaacacagcttctcggtcagccagggggaccgggagcaggta
cctaacctggtctacatggtcacaggaaaccccgcttctgatgagatcaagcggatgcct
ggagacatccaggtggtgcccatcggggtgggtccacatgccaatgtgcaggagctggag
aagattggctggcccaatgcccccatcctcatccatgactttgagatgctccctcgagag
gctcctgatctggtgctacagaggtgctgctctggagaggggctgcagatccccaccctc
tcccccaccccagattgcagccagcccctggatgtggtcctcctcctggatggctcttcc
agcattccagcttcttactttgatgaaatgaagagcttcaccaaggctttcatttcaaga
gctaatatagggccccggctcactcaagtgtcggtgctgcaatatggaagcatcaccact
atcgatgtgccttggaatgtagcctatgagaaagtccatttactgagccttgtggacctc
atgcagcaggagggaggccccagccaaattggggatgctttgagctttgccgtgcgatat
gtcacctcagaagtccatggtgccaggcccggagcctcgaaagcggtggttatcctagtc
acagatgtctccgtggattcagtggatgctgcagccgaggccgccagatccaaccgagtg
acagtgttccccattggaatcggggatcggtacagtgaggcccagctgagcagcttggca
ggcccaaaggctggctccaatatggtaaggctccagcgaattgaagacctccccaccgtg
gccaccctgggaaattccttcttccacaagctgtgctctgggtttgatagagtttgcgtg
gatgaggatgggaatgagaagaggcccggggatgtctggaccttgccagaccagtgccac
acagtgacttgcctgccagatggccagaccttgctgaagagtcatcgggtcaactgtgac
cgggggccaaggccttcgtgccccaatggccagccccctctcagggtagaggagacctgt
ggctgccgctggacctgtccctgtgtgtgcatgggcagctctacccggcacatcgtgacc
tttgatgggcagaatttcaagctgactggcagctgttcgtatgtcctatttcaaaacaag
gagcaggacctggaggtgattctccataatggtgcctgcagccctggggcgaaggagacc
tgcatgaaatccattgaggtgaagcatgacggcctctcagttgagctccacagtgacatg
cagatgacagtgaatgggagactagtctccatcccatatgtgggtggagacatggaagtc
aatgtttatgggaccatcatgtatgaggtcagattcaaccatcttggccacatcttcaca
ttcaccccccaaaacaatgagttccagctgcagctcagccccaggacctttgcttcgaag
acatatggtctctgtgggatctgtgatgagaacggagccaatgacttcattctgagggat
gggacagtcaccacagactggaaggcactcatccaggaatggaccgtacagcagcttggg
aagacatgccagcctgtccctgaggagcagtgtcctgtctccagcagttcccactgccag
gtcctcctctcagaattgtttgccgagtgccacaaggtcctcgctccagccaccttttat
gccatgtgccagcccgacagttgccacccgaagaaagtgtgtgaggcgattgccttgtat
gcccacctctgtcggaccaaaggggtctgtgtggactggaggagggccaatttctgtgct
atgtcatgtccaccatccctggtgtacaaccactgtgagcatggctgccctcggctctgt
gaaggcaatacaagctcctgtggggaccaaccctcggaaggctgcttctgccccccaaac
caagtcatgctggaaggtagctgtgtccccgaggaggcctgtacccagtgcatcagcgag
gatggagtccggcaccagttcctggaaacctgggtcccagcccaccagccttgccagatc
tgcacgtgcctcagtgggcggaaggtcaactgtacgttgcagccctgccccacagccaga
gctcccacctgtggcccgtgtgaagtggcccgcctccgccagaacgcagagcagtgctgc
ccggagtacgagtgtgtgtgtgacctggtgagctgtgacctgcccccggtgcctccctgc
gaagatggcctccagatgaccctgaccaatcctggcgagtgcagacccaacttcacctgt
gcctgcaggaaggatgaatgcagacgggagtccccgccctcttgtcccccgcaccggacg
ccggcccttcggaagactcagtgctgtgatgagtatgagtgtgcatgcaactgtgtcaac
tccacggtgagctgcctgctggggtacctggcctcggctgtcaccaacgactgtggctgc
accacaacaacctgcttccctgacaaggtgtgtgtccaccgaggcaccatctaccctgtg
ggccagttctgggaggaggcctgtgacgtgtgcacctgcacggacttggaggactctgtg
atgggcctgcgtgtggcccagtgctcccagaagccctgtgaggacaactgcctgtcgggc
ttcacttatgtccttcatgaaggcgagtgctgtggaaggtgtctgccatctgcctgtgag
gtggtcatcggttcaccacggggcgacgcccagtctcactggaagaatgttggctctcac
tgggcctcccctgacaacccctgcctcatcaatgagtgtgtccgagtgaaggaagaggtc
tttgtgcaacagaggaatgtctcctgcccccagctgaatgtccccacctgccccacgggc
ttccagctgagctgtaagacctcagagtgttgtcccacctgtcactgcgagcccctggag
gcctgcttgctcaatggtaccatcattgggccggggaaaagtctgatgattgatgtgtgt
acaacctgccgctgcaccgtccaggtgggagtcatctctggattcaagctggagtgcagg
aagaccacctgtgaggcatgccccctgggttataaggaagagaagaaccaaggtgaatgc
tgtgggagatgtctgcctatagcttgcaccattcagctaagaggaggacagatcatgaca
ctgaagcgtgatgagactatccaggatggctgtgacagtcacttctgcaaggtcaatgaa
agaggagagtacatctgggagaagagagtcacgggttgcccacctttcgatgaacacaag
tgtctggctgagggagggaaaatcatgaaaattccaggcacctgctgtgacacatgtgag
gagccagaatgcaaggatatcattgccaagctgcagcgtgtcaaagtgggagactgtaag
tctgaagaggaagtggacattcattactgtgagggtaaatgtgccagcaaagccgtgtac
tccatccacatggaggatgtgcaggaccagtgctcctgctgctcgcccacccagacggag
cccatgcaggtgcccctgcgctgcaccaatggctccctcatctaccatgagatcctcaat
gccatgcaatgcaggtgttcccccaggaagtgcagcaagtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (8)   
   KEGG PATHWAY (8)   
Genome (1)   
   KEGG GENOME (1)   
Gene (80)   
   KEGG ORTHOLOGY (1)   
   RefGene (74)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (11)   
   RefSeq(nuc) (3)   
   GenBank (4)   
   EMBL (4)   
Protein domain (8)   
   Pfam (8)   
All databases (115)   

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