KEGG   Canis lupus familiaris (dog): 403407
Entry
403407            CDS       T01007                                 
Symbol
APP
Name
(RefSeq) amyloid-beta A4 protein isoform APP-770 precursor
  KO
K04520  amyloid beta A4 protein
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04726  Serotonergic synapse
cfa05010  Alzheimer disease
cfa05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    403407 (APP)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    403407 (APP)
   05022 Pathways of neurodegeneration - multiple diseases
    403407 (APP)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:cfa01002]
    403407 (APP)
  09183 Protein families: signaling and cellular processes
   00535 Proteoglycans [BR:cfa00535]
    403407 (APP)
   00536 Glycosaminoglycan binding proteins [BR:cfa00536]
    403407 (APP)
Peptidases and inhibitors [BR:cfa01002]
 Peptidase inhibitors
  Family I2: Kunitz - BPTI family
   403407 (APP)
Proteoglycans [BR:cfa00535]
 Cell surface proteoglycans
  Others
   403407 (APP)
Glycosaminoglycan binding proteins [BR:cfa00536]
 Heparan sulfate / Heparin
  Others
   403407 (APP)
SSDB
Motif
Pfam: APP_E2 APP_N APP_Cu_bd APP_amyloid Beta-APP Kunitz_BPTI Insulin_TMD
Other DBs
NCBI-GeneID: 403407
NCBI-ProteinID: NP_001006601
Ensembl: ENSCAFG00000008557
VGNC: 38010
UniProt: A0A8C0TFV8 A0A8I3P9H6 Q56JK6 Q6RH30
Position
31:complement(21345590..21608332)
AA seq 770 aa
MLPALALVLLASWTARALEVPTDGNAGLLAEPQVAMLCGKLRMHMNVQNGKWESDPLGTK
TCIGSKEDILQYCQEVYPELQITNVVEANQPVTIQNWCKKGRKQCKTHAHIVIPYRCLVG
EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR
GVEFVCCPLAEESDNIDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVADVEEE
EAEDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPC
RAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSVMSQSLLKTTQEPLPQD
AVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQA
KNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITAL
QAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYER
MNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTET
KTTVELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTN
IKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITL
VMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
NT seq 2313 nt   +upstreamnt  +downstreamnt
atgctgcccgctttggcgctggtcctgctggcctcctggacggctcgggcgttggaggtg
cccactgacggcaatgctggcctgcttgcagaacctcaggtggccatgttgtgtggcaaa
ctacggatgcacatgaacgtgcagaatggaaaatgggagtcagaccctctggggacgaaa
acctgcatcggctccaaggaggacatcctgcagtactgccaagaagtctaccccgaactg
cagatcaccaatgtggtggaagccaaccaaccagtgaccatccagaactggtgcaagaag
ggccgcaagcagtgcaagacccacgcccacattgtgattccctaccgctgcttagttggt
gagtttgtcagtgatgccctccttgttcctgacaagtgcaaattcttacaccaggagagg
atggatgtttgtgaaacccaccttcactggcacaccgtcgccaaagagacctgtagtgag
aagagtaccaacttgcacgactatggcatgttgctgccctgtggaattgacaaattccga
ggggtggaatttgtatgttgcccgctggccgaagaaagtgacaatattgactcagcagac
gcagaggaggatgactcagatgtctggtggggtggagcagatacagactatgcagatggg
agtgaagacaaagtagtggaagtagcggaggaagaagaagtagctgatgttgaggaagag
gaagctgaggatgatgaggatgacgaagatggcgatgaggtagaggaagaggcagaagaa
ccctacgaagaggccacggagagaaccaccagcatcgccacgactaccaccaccaccact
gagtcagtggaagaggtggtccgagaggtgtgctctgaacaagccgagacggggccatgc
cgagcaatgatctcccgctggtactttgatgtgaccgaaggcaagtgcgccccgttcttt
tacggcggatgtggcggcaaccgaaacaactttgacacagaggagtactgcatggccgtg
tgtggcagcgtcatgtcccaaagtttactcaagacaacccaggaacctcttccccaagat
gctgtcaaacttcctacaacagcagccagcacccccgatgccgttgacaagtatcttgag
acacctggagatgagaatgaacatgcccatttccagaaagccaaagagaggctggaagcc
aagcaccgcgagcgaatgtcccaggtcatgcgagaatgggaagaggcagaacgacaagcc
aagaacttgcctaaggccgacaagaaagcagttattcagcatttccaggagaaggtggag
tctctggaacaagaagcagccaatgagaggcagcagctggtggagacgcacatggcccga
gtggaagccatgctcaatgaccgccgccgcctggctctggagaattacatcactgctctg
caagcggtcccaccccggcctcgtcatgtgttcaacatgctaaagaagtatgtccgtgct
gaacagaaagacaggcagcacaccctaaaacattttgaacatgtacgcatggtggatcca
aagaaagctgctcagatccggtcccaggttatgacacatctccgtgtgatttacgagcgc
atgaaccagtccctctctctgctctacaatgtgccggcagtggctgaggagattcaggat
gaagtcgatgagctgcttcagaaagagcaaaactactcggatgacgtcttggccaacatg
atcagtgaaccaagaatcagttatggaaacgatgccctcatgccatctttgacagaaacg
aaaaccaccgtggagcttcttcccgtgaatggagagttcagcctggatgatctccagccc
tggcatccttttggggtcgactcagtgccggccaacacagaaaatgaagttgagcctgtt
gatgcccgccctgccgccgaccgaggactcaccacccgaccaggttcaggcttgacaaat
atcaagacggaagagatctccgaggtgaagatggatgccgagttccgacatgactcagga
tatgaagttcatcatcaaaaattggtgttctttgcagaagatgtgggctcaaacaaaggt
gccatcattggactcatggtgggcggtgttgtcatagcaacagtgattgtcatcaccttg
gtgatgctgaagaagaagcagtacacgtccattcatcacggtgtggtggaggttgacgct
gctgtgaccccagaggagcgccacctctccaagatgcagcagaatggctatgaaaaccca
acttacaagttcttcgagcagatgcagaactag

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (3)   
   KEGG PATHWAY (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (11)   
   UniProt (4)   
   RefSeq(pep) (7)   
DNA sequence (29)   
   RefSeq(nuc) (7)   
   GenBank (11)   
   EMBL (11)   
Protein domain (7)   
   Pfam (7)   
All databases (65)   

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