KEGG   Canis lupus familiaris (dog): 403416
Entry
403416            CDS       T01007                                 
Symbol
BCL2
Name
(RefSeq) apoptosis regulator Bcl-2
  KO
K02161  apoptosis regulator Bcl-2
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa01521  EGFR tyrosine kinase inhibitor resistance
cfa01522  Endocrine resistance
cfa01524  Platinum drug resistance
cfa04064  NF-kappa B signaling pathway
cfa04066  HIF-1 signaling pathway
cfa04071  Sphingolipid signaling pathway
cfa04115  p53 signaling pathway
cfa04140  Autophagy - animal
cfa04141  Protein processing in endoplasmic reticulum
cfa04151  PI3K-Akt signaling pathway
cfa04210  Apoptosis
cfa04215  Apoptosis - multiple species
cfa04217  Necroptosis
cfa04261  Adrenergic signaling in cardiomyocytes
cfa04340  Hedgehog signaling pathway
cfa04510  Focal adhesion
cfa04621  NOD-like receptor signaling pathway
cfa04630  JAK-STAT signaling pathway
cfa04722  Neurotrophin signaling pathway
cfa04725  Cholinergic synapse
cfa04915  Estrogen signaling pathway
cfa04928  Parathyroid hormone synthesis, secretion and action
cfa04933  AGE-RAGE signaling pathway in diabetic complications
cfa05014  Amyotrophic lateral sclerosis
cfa05022  Pathways of neurodegeneration - multiple diseases
cfa05132  Salmonella infection
cfa05145  Toxoplasmosis
cfa05152  Tuberculosis
cfa05161  Hepatitis B
cfa05162  Measles
cfa05168  Herpes simplex virus 1 infection
cfa05169  Epstein-Barr virus infection
cfa05170  Human immunodeficiency virus 1 infection
cfa05200  Pathways in cancer
cfa05206  MicroRNAs in cancer
cfa05207  Chemical carcinogenesis - receptor activation
cfa05210  Colorectal cancer
cfa05215  Prostate cancer
cfa05222  Small cell lung cancer
cfa05226  Gastric cancer
cfa05417  Lipid and atherosclerosis
cfa05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    403416 (BCL2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04340 Hedgehog signaling pathway
    403416 (BCL2)
   04630 JAK-STAT signaling pathway
    403416 (BCL2)
   04064 NF-kappa B signaling pathway
    403416 (BCL2)
   04066 HIF-1 signaling pathway
    403416 (BCL2)
   04071 Sphingolipid signaling pathway
    403416 (BCL2)
   04151 PI3K-Akt signaling pathway
    403416 (BCL2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    403416 (BCL2)
  09143 Cell growth and death
   04210 Apoptosis
    403416 (BCL2)
   04215 Apoptosis - multiple species
    403416 (BCL2)
   04217 Necroptosis
    403416 (BCL2)
   04115 p53 signaling pathway
    403416 (BCL2)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    403416 (BCL2)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    403416 (BCL2)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    403416 (BCL2)
   04928 Parathyroid hormone synthesis, secretion and action
    403416 (BCL2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    403416 (BCL2)
  09156 Nervous system
   04725 Cholinergic synapse
    403416 (BCL2)
   04722 Neurotrophin signaling pathway
    403416 (BCL2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    403416 (BCL2)
   05206 MicroRNAs in cancer
    403416 (BCL2)
   05207 Chemical carcinogenesis - receptor activation
    403416 (BCL2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    403416 (BCL2)
   05226 Gastric cancer
    403416 (BCL2)
   05215 Prostate cancer
    403416 (BCL2)
   05222 Small cell lung cancer
    403416 (BCL2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    403416 (BCL2)
   05161 Hepatitis B
    403416 (BCL2)
   05162 Measles
    403416 (BCL2)
   05168 Herpes simplex virus 1 infection
    403416 (BCL2)
   05169 Epstein-Barr virus infection
    403416 (BCL2)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    403416 (BCL2)
   05152 Tuberculosis
    403416 (BCL2)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    403416 (BCL2)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    403416 (BCL2)
   05022 Pathways of neurodegeneration - multiple diseases
    403416 (BCL2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    403416 (BCL2)
   05418 Fluid shear stress and atherosclerosis
    403416 (BCL2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    403416 (BCL2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    403416 (BCL2)
   01524 Platinum drug resistance
    403416 (BCL2)
   01522 Endocrine resistance
    403416 (BCL2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:cfa01009]
    403416 (BCL2)
Protein phosphatases and associated proteins [BR:cfa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     403416 (BCL2)
SSDB
Motif
Pfam: Bcl-2 BH4 Bcl-2_3
Other DBs
NCBI-GeneID: 403416
NCBI-ProteinID: NP_001002949
VGNC: 54274
UniProt: Q75SV7
Position
1:14699877..14866689
AA seq 239 aa
MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGEAGAAPPGAAPAPGIFSSQPGRAPAPA
RTSPPPPPAAPAAAAAAAADAAGPAPSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH
LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY
LNRHLHTWIQDNGGWDAFVELYGPTMQPLFDFSWLSLKALLSLALVGACITLGAYLGHK
NT seq 720 nt   +upstreamnt  +downstreamnt
atggcgcacgctgggcgaacagggtacgataaccgggagatagtgatgaagtacatccac
tacaagctgtcgcagaggggctacgagtgggacgcgggagaggcgggcgccgcgcccccg
ggggccgcccccgcgccgggcatcttctcctcgcagcccggccgcgcccccgcgcccgcc
aggacctcgccgcccccgccccccgccgcccccgctgccgccgccgccgccgccgccgac
gccgcgggccccgcgcccagccccgtgccacctgtggtccacctgaccctgcgccaggcc
ggcgacgacttctcccgccgctaccgccgcgacttcgccgagatgtccagccagctgcac
ctgacgcccttcaccgcgaggggacgctttgccacggtggtggaggagctcttcagggat
ggggtgaactgggggaggattgtggccttctttgagttcggtggggtcatgtgtgtggag
agcgtcaaccgggagatgtcgcccctggtggacaacatcgccctgtggatgactgagtac
ctgaaccggcatctgcacacctggatccaggacaacggaggctgggatgcctttgtggaa
ctgtacggccccaccatgcagcctctgtttgacttctcctggctgtctctgaaggcgctg
ctcagtctggccctggtgggagcttgcatcaccctgggtgcctatctgggccataagtga

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