KEGG   Canis lupus familiaris (dog): 403426
Entry
403426            CDS       T01007                                 
Symbol
PLAU
Name
(RefSeq) urokinase-type plasminogen activator precursor
  KO
K01348  urokinase plasminogen activator [EC:3.4.21.73]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04064  NF-kappa B signaling pathway
cfa04610  Complement and coagulation cascades
cfa05202  Transcriptional misregulation in cancer
cfa05205  Proteoglycans in cancer
cfa05206  MicroRNAs in cancer
cfa05215  Prostate cancer
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    403426 (PLAU)
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    403426 (PLAU)
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    403426 (PLAU)
   05206 MicroRNAs in cancer
    403426 (PLAU)
   05205 Proteoglycans in cancer
    403426 (PLAU)
  09162 Cancer: specific types
   05215 Prostate cancer
    403426 (PLAU)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:cfa01002]
    403426 (PLAU)
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins [BR:cfa00536]
    403426 (PLAU)
Enzymes [BR:cfa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.73  u-plasminogen activator
     403426 (PLAU)
Peptidases and inhibitors [BR:cfa01002]
 Serine peptidases
  Family S1: chymotrypsin family
   403426 (PLAU)
Glycosaminoglycan binding proteins [BR:cfa00536]
 Heparan sulfate / Heparin
  Coagulation and fibrinolysis
   403426 (PLAU)
SSDB
Motif
Pfam: Trypsin Kringle DUF316 Trypsin_2 DUF1986
Other DBs
NCBI-GeneID: 403426
NCBI-ProteinID: NP_001181881
VGNC: 52017
UniProt: A0A8C0RW08 A0A8I3NA75 Q6SLL2
Position
4:24466425..24471181
AA seq 428 aa
MRALMTCLLLGALVGSHEFHPVSSASNCSCLNGGTCVSYKYFSNIQRCNCPKKFQGEHCE
IDTSKTCYEGNGHSYRGKANTNTRGRPCLAWNSAAVLLKQYHALRPDALQLGLGKHNYCR
NPDHQRKPWCYVQVGLMQLVQECTVQHCSFEKNPHSPPEKAEFQCGQKALRPRFKIIGGE
FTTIENQPWFAAIYRKHRGGSVTYQCGGSLISPCWVVSATHCFINSQKKDDYIVYLGRSK
RISKTFGEMKFEVEKLILHEDYSADSLAHHNDIALLKIRSDEGQCAQPSRSIQTICLPPS
RGDAHFGASCEISGFGKENSTDYLYPEQLKMTVVKLVSHQECQQPHYYGSEVTDQMLCAA
DPEWETDSCQGDSGGPLVCSTQGRLTLTGIVSWGSGCAMKNKPGVYTRVSRFLPWIHRHI
GEQNGLTL
NT seq 1287 nt   +upstreamnt  +downstreamnt
atgagagccctgatgacgtgcctgctcctgggcgccctagtgggcagccatgagtttcat
ccagtgtctagcgcatcaaactgcagctgtctgaacggaggaacgtgcgtgtcctacaag
tacttctccaacattcagcgatgcaactgcccaaagaaattccagggggaacactgtgag
atagatacatcaaaaacctgctacgaggggaatggtcactcttaccgcgggaaggccaac
accaacaccaggggccggccctgcctggcctggaactccgcagctgttcttctgaaacag
taccatgccctcagacctgatgcccttcagctgggcctgggcaaacacaattactgcagg
aacccggaccaccagagaaagccgtggtgctatgtgcaggttggcctgatgcagcttgtc
caggagtgcacggtgcagcactgctcttttgaaaaaaatccccactctcctccagaaaaa
gcagagtttcaatgtggccagaaggctctgaggcctcgctttaagattattggtggagaa
ttcaccaccatcgagaaccagccttggtttgcagccatctacaggaagcaccgtggaggc
tctgtcacctatcagtgtggtggcagcctcattagtccttgctgggtggtcagcgccaca
cactgcttcattaattcccagaagaaggatgactacattgtctacctgggtcggtcaaag
cgtatctccaaaacatttggggagatgaagtttgaggtggaaaagctcatcttgcatgag
gactatagtgctgacagtcttgctcaccacaatgatattgccttgctgaagatccgttct
gatgagggccagtgtgcacagccatccaggtccatacaaaccatctgcctccctccatca
cgtggtgatgctcattttggtgcaagctgtgagatcagtggctttggaaaagagaattcc
actgactatctctatccagagcagctgaaaatgactgttgtgaagctggtttcccaccag
gagtgtcagcagccccactactatggctctgaagtcaccgaccaaatgctgtgtgctgct
gacccagagtgggaaacagattcctgccagggagactccggggggcccctggtctgctct
acccaaggccgcctgactctgactgggattgtgagctggggcagtggatgtgccatgaag
aacaagccaggcgtctacacaagggtctcacgcttcctgccttggatccacaggcacata
ggggaacagaatggcctaaccctctga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (41)   
   KEGG ORTHOLOGY (1)   
   RefGene (36)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (4)   
   UniProt (3)   
   RefSeq(pep) (1)   
DNA sequence (9)   
   RefSeq(nuc) (1)   
   GenBank (4)   
   EMBL (4)   
Protein domain (5)   
   Pfam (5)   
All databases (71)   

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