KEGG   Canis lupus familiaris (dog): 403445
Entry
403445            CDS       T01007                                 
Symbol
MMP3
Name
(RefSeq) stromelysin-1 precursor
  KO
K01394  matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04657  IL-17 signaling pathway
cfa04668  TNF signaling pathway
cfa05171  Coronavirus disease - COVID-19
cfa05202  Transcriptional misregulation in cancer
cfa05215  Prostate cancer
cfa05323  Rheumatoid arthritis
cfa05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    403445 (MMP3)
 09150 Organismal Systems
  09151 Immune system
   04657 IL-17 signaling pathway
    403445 (MMP3)
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    403445 (MMP3)
  09162 Cancer: specific types
   05215 Prostate cancer
    403445 (MMP3)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    403445 (MMP3)
  09163 Immune disease
   05323 Rheumatoid arthritis
    403445 (MMP3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    403445 (MMP3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:cfa01002]
    403445 (MMP3)
Enzymes [BR:cfa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.17  stromelysin 1
     403445 (MMP3)
Peptidases and inhibitors [BR:cfa01002]
 Metallo peptidases
  Family M10
   403445 (MMP3)
SSDB
Motif
Pfam: Peptidase_M10 Hemopexin PG_binding_1 Astacin Reprolysin_3 DUF4953 Reprolysin_5 Reprolysin_4
Other DBs
NCBI-GeneID: 403445
NCBI-ProteinID: NP_001002967
Ensembl: ENSCAFG00000015063
UniProt: Q6Y4Q5
Position
5:28898123..28906399
AA seq 478 aa
MQNLPALLLFCGVVCSAYPVDRAAEDENNNMELTQQYLENYYNLGKDVKPFVRRRNSGPV
VEKIREMQKFLGLEVTGKVDSDTLAMMRRPRCGVPDVGDFTTFPGMPKWRKTHLTYRIMN
YTPDLPRDAVDSAIEKALNVWKEVTPLTFSRTDEGEADIKISFAVRDHGDFNPFDGPGNV
LGHAYPPGPGIYGDAHFDDDEQWTSDTSGTNLFLVAAHELGHSLGLFHSADPSALMYPVY
NVLADLARFHLSQDDVNGIQSLYGGPPSDSSNDPVVPTESVPPGPGTPAACDPTLSFDAI
STLRGEFLFFKDRHFWRKSLRTLEPGFYLISSFWPSLPSGLDAAYEETSKDIVFIFKGNQ
FWAMRGTEVQAGYPKGIHTLGFPPTVKKIDAAVFDKEKKKTYFFVGDKYWRFDEKRQSME
PGFPKQIAEDFPGVDSKVDAAFEAFGFYYFFNGSSQLEFDPNAKKVTHVLKSNSWLNC
NT seq 1437 nt   +upstreamnt  +downstreamnt
atgcagaaccttccagctctactgctcttctgtggggttgtgtgctcagcctatccagtg
gacagagctgcagaggatgagaacaacaacatggaactcacccagcaatacctagaaaac
tactacaaccttgggaaagatgtgaaaccatttgtcagaagaaggaacagtggtcctgtc
gttgaaaaaatccgagaaatgcagaagttcctcgggttggaggtgacagggaaggtggac
tcggacaccctggcgatgatgcgcaggcccaggtgtggcgttcctgacgtcggtgacttc
accaccttccctggcatgcccaagtggaggaaaactcaccttacttacagaatcatgaat
tatacaccagatttgccaagagatgctgttgattctgccattgagaaagctctgaatgtc
tggaaggaggtgactccacttactttctccaggactgatgaaggagaggctgacataaag
atttcttttgcagttagagatcacggagactttaacccttttgatggacctggaaatgtt
ttgggtcatgcctacccacctgggcctggcatttatggagatgcccactttgacgatgat
gaacaatggacaagcgatacatcaggaaccaatttattcctcgttgctgctcatgagctt
ggccattccctgggtctctttcactcggctgaccctagcgctctgatgtacccagtctac
aatgtattggcagatctggcccgcttccatctttctcaagatgatgtgaatggcatccag
tccctgtatggtggacctccctctgattcctccaatgaccccgtggtgcccacggaatct
gtgcctccaggacctgggacaccagctgcatgtgaccccactttgtccttcgacgcaatc
agcaccctgaggggagagttcctgttctttaaagacagacatttttggcgaaaatccctc
aggacacttgaacctgggttctatttaatctcttcattttggccatcccttccttcaggc
ttggatgccgcatatgaagagactagcaaggatattgttttcatttttaaaggaaatcag
ttctgggccatgagaggaactgaggtacaagccggttatccaaaaggcatccacaccctg
ggttttcctccaaccgtgaagaaaattgatgcagctgtttttgataaggagaagaagaaa
acgtacttcttcgtaggagacaaatactggcgatttgatgagaagagacaatccatggag
ccaggctttcccaagcaaatagcagaagactttccaggggttgactcgaaggttgatgct
gcgtttgaggcatttgggttttactacttcttcaatggatcttcacagttggagtttgac
ccaaatgcaaagaaagtgacacatgttttgaagagcaacagctggcttaattgttga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (7)   
   KEGG PATHWAY (7)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (8)   
   Pfam (8)   
All databases (37)   

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