KEGG   Canis lupus familiaris (dog): 403698
Entry
403698            CDS       T01007                                 
Symbol
NPC1
Name
(RefSeq) NPC intracellular cholesterol transporter 1 precursor
  KO
K12385  Niemann-Pick C1 protein
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa03265  Virion - Ebolavirus and Lyssavirus
cfa04142  Lysosome
cfa04979  Cholesterol metabolism
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03265 Virion - Ebolavirus and Lyssavirus
    403698 (NPC1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome
    403698 (NPC1)
 09150 Organismal Systems
  09154 Digestive system
   04979 Cholesterol metabolism
    403698 (NPC1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:cfa02000]
    403698 (NPC1)
Transporters [BR:cfa02000]
 Solute carrier family (SLC)
  SLC65: NPC-type cholesterol transporter
   403698 (NPC1)
SSDB
Motif
Pfam: Patched NPC1_N Sterol-sensing MMPL ACR_tran
Other DBs
NCBI-GeneID: 403698
NCBI-ProteinID: NP_001003107
Ensembl: ENSCAFG00000018183
VGNC: 43913
UniProt: Q9GK52
Position
7:64198337..64251229
AA seq 1276 aa
MTARRPAVGLVLLLLCPAQVFAQSCVWYGECGIASGDKRYNCQYSGPPKPLPKDGYDLMQ
ELCPGLFFDNVSVCCDVQQLRTLKDSLQLPLQFLSRCPSCFYNLMNLFCELTCSPRQSQF
LNVTETEDYVDPVTNQTKTNVKELQYYVGESFANAMYNACRDVEAPSSNDKALGLLCGKE
AEACNATNWIEYMFNKDNGQAPFTIIPIFSDLPAHGMKPMNNATKGCDEPVDEVTAPCSC
QDCSVVCGPKPQPPPAPAPWRILGLDAMYVIMWITYMAFLLMFFGAFFAVWCYRKRYFVS
EYTPIDSNIAFSVNAGDTGEASCCDALGAAFEGCLRRLFTQWGSFCIRNPGCIIFFSLAF
IAACSSGLVFSRVTTNPVDLWSAPGSQARLEKEYFDAHFGPFFRTEQLIIQAPHTSVHTY
QPYPSGSDVPFGPPLDIGILHQVLDLQTAIENITATYNNETVTLQDICVAPLSPYNKNCT
IMSVLNYFQNSHSMLDHKIGDDFYVYADYHTHLLYCVRAPASLNDTSLLHDPCLGTFGGP
VFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTEKLQRAQAWEKEFINFVKNYENPNLT
ISFTTERSIEDELNRESNGDVFTVLISYAVMFLYISIALGHIKSCSRFLVDSKISLGIAG
ILIVLSSVMCSLGIFSYFGIPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLQGETL
EQQLGRVLGEVAPSMFLSSFSEAVAFFLGALSQMPAVHTFSLFAGMAVLIDFLLQITCFV
SLLGLDLKRQEKNRLDVLCCLTGSEGGTGIQASESCLFRFFKNSYSPFLLKDWMRPIVIA
VFVGILSFSIAVLNKVEIGLDQSLSMPDDSYMMDYFKSLKYLHAGPPVYFVLEEGHDYTS
LEGQNMVCGGMGCNNDSLVQQIFSAAQLDNYTHIGFAPSSWIDDYFDWVKPQSSCCRVYN
STDQFCNASVVDPACVRCRPLTQEGKRRPQGEDFMRFLPMFLSDNPNPKCGKGGHAAYGS
AVNLVGNDTSVGATYFMTYHTVLQTSADFTDAMRKAILIASNITKTMSLKGSHYRVFPYS
VFYVFYEQYLTIIDDTIFNLSVSLGAIFLVTLVLLGCELWSAVIMCVTIAMILVNMFGVM
WLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSAKGSRVERAEEALSHMGSSVFSGI
TLTKFGGIVVLAFAKSQIFQVFYFRMYLAMVLLGATHGLIFLPVLLSYIGPSINKAKSLA
SQERYKGTEREQLLNF
NT seq 3831 nt   +upstreamnt  +downstreamnt
atgaccgcccgccgccccgccgtcggcctcgtcctgctgctgctctgccccgcgcaggtg
tttgcacagtcctgtgtatggtatggagagtgtggaattgcatctggagacaagaggtat
aactgccaatattcggggccaccaaaacccttgccaaaggatgggtatgacttaatgcag
gagctctgtccaggattattctttgacaatgtcagcgtgtgctgtgacgtgcagcagctc
cggactctgaaggacagcctacagcttcccctgcagttcctgtccagatgtccatcctgt
ttttataacctaatgaacctgttttgcgagctgacatgtagccctcggcaaagtcagttt
ctgaatgttacagaaactgaagattatgttgatcctgttacaaaccagacaaaaacgaac
gtaaaagaattacagtactatgtcggagagagttttgccaatgccatgtacaacgcctgc
cgggacgtggaggccccctccagtaatgacaaagccctgggactcctgtgtgggaaggag
gccgaggcctgcaatgccaccaactggatcgagtacatgttcaataaggacaacggccag
gcacctttcaccatcatacccatattttcagatcttccagcccatgggatgaagcccatg
aacaatgccaccaagggctgtgacgagcctgtggacgaggtcacggcaccgtgcagttgc
caagattgctcggtggtctgtggccccaagccccagcccccacccgctccggctccctgg
agaattttgggcctggatgccatgtatgtcatcatgtggatcacctacatggcatttttg
ctcatgttttttggagcattttttgctgtgtggtgctacagaaaacgctattttgtctct
gagtacacccccattgatagcaacatagctttctctgtaaatgccggtgacacaggggag
gcatcctgctgcgacgcacttggtgcagcatttgagggctgcctgaggcggctcttcaca
cagtggggctccttctgcatccgaaacccaggctgcatcatcttcttctccctggccttc
attgctgcctgctcttcaggcctggtgttcagccgggtcacgaccaacccagtggacctg
tggtcggcccctggcagccaggcacgcctggagaaagagtactttgatgcgcacttcggg
cctttcttccgcacggagcagctcatcatccaggccccccacaccagtgtgcacacttac
cagccgtacccctcaggatctgacgtgccctttgggcccccgcttgacatagggatcttg
caccaggttctagacttacaaaccgccattgaaaacatcaccgcaacttacaacaacgag
actgtaacacttcaagacatctgtgtggccccgctctcaccctataacaagaactgcacc
attatgagcgtgttaaattacttccagaacagccattctatgttggaccacaaaataggg
gatgacttctatgtgtatgcagattaccacacgcacttgctatattgtgtacgggctcct
gcatctctgaatgataccagtttgctccatgatccttgcctgggtacatttggtgggcca
gtgttcccgtggcttgtgttaggaggctatgatgatcaaaactacaataatgctacagcc
cttgtgattacctttcctgtcaataattactacaatgatacagagaagctccagagggcc
caggcctgggaaaaagagtttattaattttgtgaaaaactacgagaatccaaatctgacc
atttctttcactactgagcgaagtattgaggatgaactgaatcgggaaagtaacggtgat
gtcttcactgttctgatcagctatgccgtcatgtttctatacatttccatagccttgggg
cacatcaaaagctgtagcaggtttctagtggattctaaaatctcccttggcatcgctggg
atcctcattgtgttgagctcagtgatgtgctcattgggcatcttcagctactttgggatc
cccctcaccctcatcgtgatcgaagtcatcccattcctggtgttggctgttggggtagac
aacatcttcattctggtccaaacctaccagcgcgatgaacgtcttcaaggagaaactctg
gaacagcagctgggcagggtcctaggagaagtggctcctagtatgttcctgtcctccttt
tcagaggctgtagcatttttcttaggagccttgtcacagatgcccgcagtgcacactttc
tctctgtttgccgggatggcggtcctcattgacttccttcttcagattacctgttttgtg
agtctcttggggttagaccttaagcgtcaagagaaaaatcgcctggacgtcctttgctgt
ctcacaggctctgaaggtggaaccggcatccaggcctcagaaagctgcttatttcggttc
ttcaaaaactcctactccccatttctgcttaaggattggatgcggcccattgtgatagcg
gtatttgtgggcattctctcattcagtatcgcagtcctgaacaaagtggagattggattg
gatcagtctctttcaatgccagatgactcctacatgatggattatttcaagtccctcaaa
tacctgcatgcaggtccccccgtgtactttgtcctcgaggaaggacacgattacacctct
ttggaagggcagaacatggtgtgcgggggcatgggctgcaataatgactccctggtgcag
cagatcttcagcgcggctcagctggacaactatacccacataggctttgcgccctcgtcc
tggatcgacgattattttgattgggtcaagcctcagtcttcctgctgtagagtctacaac
agcacagatcagttctgcaacgcctcagtggttgaccctgcctgcgtccgctgcaggcct
ctgacccaggagggcaaacggaggcctcaaggtgaagacttcatgagattcctgcccatg
ttcctttctgataacccaaaccccaagtgcggcaaagggggacatgctgcctacggctca
gcagttaacctcgtcggcaatgacacgagtgtcggagccacttacttcatgacctaccac
accgtgcttcagacctctgctgactttactgacgccatgagaaaagccatcctcattgcc
agtaacatcaccaaaaccatgagccttaaaggaagccactaccgcgtgttcccgtacagt
gtgttctatgtcttctacgaacagtacctgaccattattgatgacacgatctttaacctt
agcgtgtcactgggagccatcttcttggtgaccttggttctcctgggctgtgaactgtgg
tctgcagtgatcatgtgtgtcaccattgccatgatcttggtcaacatgtttggcgtcatg
tggctgtggggcatcagtctgaacgcggtttccttggtcaacctggtcatgagctgtggc
atctccgtggagttctgcagccacataacgagagcgttcacagtgagtgcgaagggcagc
cgcgtggaacgggccgaagaggcgctctctcacatgggcagttctgtgttcagtggaatc
acactaacgaaatttggagggattgtggtgttggcctttgccaaatcgcagattttccag
gtattttacttcaggatgtatctggctatggtcttgctgggagccacgcacggcttgata
ttcctccctgtgttactcagctacataggcccatcaataaataaagccaaaagtttggcc
tcccaggagcgatacaaaggtacagagcgagagcagctcctgaacttctag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (27)   
   KEGG ORTHOLOGY (1)   
   RefGene (21)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (7)   
   RefSeq(nuc) (1)   
   GenBank (3)   
   EMBL (3)   
Protein domain (5)   
   Pfam (5)   
All databases (47)   

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