KEGG   Canis lupus familiaris (dog): 403974
Entry
403974            CDS       T01007                                 
Symbol
IL1B
Name
(RefSeq) interleukin-1 beta
  KO
K04519  interleukin 1 beta
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa01523  Antifolate resistance
cfa04010  MAPK signaling pathway
cfa04060  Cytokine-cytokine receptor interaction
cfa04064  NF-kappa B signaling pathway
cfa04217  Necroptosis
cfa04380  Osteoclast differentiation
cfa04620  Toll-like receptor signaling pathway
cfa04621  NOD-like receptor signaling pathway
cfa04623  Cytosolic DNA-sensing pathway
cfa04625  C-type lectin receptor signaling pathway
cfa04640  Hematopoietic cell lineage
cfa04657  IL-17 signaling pathway
cfa04659  Th17 cell differentiation
cfa04668  TNF signaling pathway
cfa04750  Inflammatory mediator regulation of TRP channels
cfa04932  Non-alcoholic fatty liver disease
cfa04933  AGE-RAGE signaling pathway in diabetic complications
cfa04936  Alcoholic liver disease
cfa04940  Type I diabetes mellitus
cfa05010  Alzheimer disease
cfa05020  Prion disease
cfa05022  Pathways of neurodegeneration - multiple diseases
cfa05132  Salmonella infection
cfa05133  Pertussis
cfa05134  Legionellosis
cfa05135  Yersinia infection
cfa05140  Leishmaniasis
cfa05142  Chagas disease
cfa05143  African trypanosomiasis
cfa05144  Malaria
cfa05146  Amoebiasis
cfa05152  Tuberculosis
cfa05162  Measles
cfa05163  Human cytomegalovirus infection
cfa05164  Influenza A
cfa05168  Herpes simplex virus 1 infection
cfa05171  Coronavirus disease - COVID-19
cfa05321  Inflammatory bowel disease
cfa05323  Rheumatoid arthritis
cfa05332  Graft-versus-host disease
cfa05417  Lipid and atherosclerosis
cfa05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    403974 (IL1B)
   04064 NF-kappa B signaling pathway
    403974 (IL1B)
   04668 TNF signaling pathway
    403974 (IL1B)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    403974 (IL1B)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    403974 (IL1B)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    403974 (IL1B)
   04620 Toll-like receptor signaling pathway
    403974 (IL1B)
   04621 NOD-like receptor signaling pathway
    403974 (IL1B)
   04623 Cytosolic DNA-sensing pathway
    403974 (IL1B)
   04625 C-type lectin receptor signaling pathway
    403974 (IL1B)
   04659 Th17 cell differentiation
    403974 (IL1B)
   04657 IL-17 signaling pathway
    403974 (IL1B)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    403974 (IL1B)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    403974 (IL1B)
 09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    403974 (IL1B)
   05164 Influenza A
    403974 (IL1B)
   05162 Measles
    403974 (IL1B)
   05168 Herpes simplex virus 1 infection
    403974 (IL1B)
   05163 Human cytomegalovirus infection
    403974 (IL1B)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    403974 (IL1B)
   05135 Yersinia infection
    403974 (IL1B)
   05133 Pertussis
    403974 (IL1B)
   05134 Legionellosis
    403974 (IL1B)
   05152 Tuberculosis
    403974 (IL1B)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    403974 (IL1B)
   05144 Malaria
    403974 (IL1B)
   05140 Leishmaniasis
    403974 (IL1B)
   05142 Chagas disease
    403974 (IL1B)
   05143 African trypanosomiasis
    403974 (IL1B)
  09163 Immune disease
   05323 Rheumatoid arthritis
    403974 (IL1B)
   05321 Inflammatory bowel disease
    403974 (IL1B)
   05332 Graft-versus-host disease
    403974 (IL1B)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    403974 (IL1B)
   05020 Prion disease
    403974 (IL1B)
   05022 Pathways of neurodegeneration - multiple diseases
    403974 (IL1B)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    403974 (IL1B)
   05418 Fluid shear stress and atherosclerosis
    403974 (IL1B)
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    403974 (IL1B)
   04936 Alcoholic liver disease
    403974 (IL1B)
   04932 Non-alcoholic fatty liver disease
    403974 (IL1B)
   04933 AGE-RAGE signaling pathway in diabetic complications
    403974 (IL1B)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    403974 (IL1B)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:cfa04052]
    403974 (IL1B)
   00536 Glycosaminoglycan binding proteins [BR:cfa00536]
    403974 (IL1B)
Cytokines and neuropeptides [BR:cfa04052]
 Cytokines
  Interleukins
   403974 (IL1B)
Glycosaminoglycan binding proteins [BR:cfa00536]
 Heparan sulfate / Heparin
  Cytokines
   403974 (IL1B)
SSDB
Motif
Pfam: IL1 IL1_propep CoV_Methyltr_2
Other DBs
NCBI-GeneID: 403974
NCBI-ProteinID: NP_001033060
Ensembl: ENSCAFG00000007249
VGNC: 41957
UniProt: Q2VCE2
Position
17:complement(36788618..36793136)
AA seq 265 aa
MAAVPELTSEMMAYSSNNENDLFFEADGPGNVKCCCQDLNHSSLVDEGIQLQVSHQLCNK
SLRHFVSVIVALEKLKKPCPQVLQEDDLKSIFCYIFEEEPIICKTDADNFMSDAAMQSVD
CKLQDISHKYLVLSNSYELRALHLNGENVNKQVVFHMSFVHGDESNNKIPVVLGIKQKNL
YLSCVMKDGKPTLQLEKVDPKVYPKRKMEKRFVFNKIEIKNTVEFESSQYPNWYISTSQV
EGMPVFLGNTRGGQDITDFTMEFSS
NT seq 798 nt   +upstreamnt  +downstreamnt
atggcagcagtacccgaactcaccagtgaaatgatggcttactccagtaacaatgagaat
gacctattctttgaagctgatggccctggaaatgtgaagtgctgctgccaagacctgaac
cacagttctctggtagatgagggcatccagttgcaagtctcccaccagctctgtaacaag
agtctgaggcatttcgtgtcagtcattgtagctttggagaagctgaagaagccctgccca
caggtcctccaggaggatgacctgaagagcatcttttgctacatctttgaagaagaacct
atcatctgcaaaacagatgcggataattttatgagtgatgcagccatgcaatcggtggac
tgcaagttacaggacataagccacaaatacctggtgctgtctaactcatatgagcttcgg
gctctccacctcaatggggaaaatgtgaacaaacaagtggtgttccacatgagctttgtg
cacggggatgaaagtaataacaagatacctgtggtcttgggcatcaaacaaaagaatctg
tacctgtcctgtgtgatgaaggatggaaagcccaccctacagctagagaaggtagacccc
aaagtctacccaaagaggaagatggaaaagcgatttgtcttcaacaagatagaaatcaag
aacacagtggaatttgagtcttctcagtaccctaactggtacatcagcacctctcaagtc
gaaggaatgcctgtcttcctaggaaataccagaggtggccaggatataactgacttcacc
atggaattctcttcctag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (42)   
   KEGG PATHWAY (42)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (18)   
   RefSeq(nuc) (2)   
   GenBank (8)   
   EMBL (8)   
Protein domain (3)   
   Pfam (3)   
All databases (79)   

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