KEGG   Canis lupus familiaris (dog): 442985
Entry
442985            CDS       T01007                                 
Symbol
PDGFRB
Name
(RefSeq) platelet-derived growth factor receptor beta precursor
  KO
K05089  platelet-derived growth factor receptor beta [EC:2.7.10.1]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa01521  EGFR tyrosine kinase inhibitor resistance
cfa04010  MAPK signaling pathway
cfa04014  Ras signaling pathway
cfa04015  Rap1 signaling pathway
cfa04020  Calcium signaling pathway
cfa04072  Phospholipase D signaling pathway
cfa04151  PI3K-Akt signaling pathway
cfa04510  Focal adhesion
cfa04540  Gap junction
cfa04630  JAK-STAT signaling pathway
cfa04810  Regulation of actin cytoskeleton
cfa05165  Human papillomavirus infection
cfa05200  Pathways in cancer
cfa05206  MicroRNAs in cancer
cfa05214  Glioma
cfa05215  Prostate cancer
cfa05218  Melanoma
cfa05230  Central carbon metabolism in cancer
cfa05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    442985 (PDGFRB)
   04014 Ras signaling pathway
    442985 (PDGFRB)
   04015 Rap1 signaling pathway
    442985 (PDGFRB)
   04630 JAK-STAT signaling pathway
    442985 (PDGFRB)
   04020 Calcium signaling pathway
    442985 (PDGFRB)
   04072 Phospholipase D signaling pathway
    442985 (PDGFRB)
   04151 PI3K-Akt signaling pathway
    442985 (PDGFRB)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    442985 (PDGFRB)
   04540 Gap junction
    442985 (PDGFRB)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    442985 (PDGFRB)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    442985 (PDGFRB)
   05206 MicroRNAs in cancer
    442985 (PDGFRB)
   05230 Central carbon metabolism in cancer
    442985 (PDGFRB)
   05231 Choline metabolism in cancer
    442985 (PDGFRB)
  09162 Cancer: specific types
   05214 Glioma
    442985 (PDGFRB)
   05218 Melanoma
    442985 (PDGFRB)
   05215 Prostate cancer
    442985 (PDGFRB)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    442985 (PDGFRB)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    442985 (PDGFRB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cfa01001]
    442985 (PDGFRB)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:cfa04090]
    442985 (PDGFRB)
Enzymes [BR:cfa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     442985 (PDGFRB)
Protein kinases [BR:cfa01001]
 Receptor tyrosine kinases (RTK)
  PDGFR family [OT]
   442985 (PDGFRB)
CD molecules [BR:cfa04090]
 Proteins
  442985 (PDGFRB)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase Ig_3 ig I-set Ig_2 V-set VEGFR-1-like_Ig-like TrmE_N Haspin_kinase
Other DBs
NCBI-GeneID: 442985
NCBI-ProteinID: NP_001003382
Ensembl: ENSCAFG00000018214
VGNC: 44373
UniProt: Q6QNF3
Position
4:58692327..58728259
AA seq 1103 aa
MQVPGTMPAPVLKGQALWLPLLLMLSPQASGGLVITPPGPELVLNISSTFVLTCSGPAPV
VWERLSQEPLQKMARTQDGTFSSTLTLTNVTGLDTGEYFCTYKGSHGLEPDGRKRLYIFV
PDPTMGFLPVDPEELFIFLTEITEITIPCRVTDPRLVVTLHEKKVDIPLPIPYDHQRGFS
GTFEDKTYVCKTTIGDKEVDSEAYYVYSLQVSSINVSVNAVQTVVRQGENITIMCIVTGN
EVVNFEWTYPRMESGRLVEPVTDFLFNVPSHIRSILHIPSAELGDSGTYICNVSESVNDH
RDEKSINVTVVESGYVRLLGELDAVQFAELHRSRALQVVFEAYPPPTVVWFKDNRTLGDS
SAGEIALSTRNVSETRYVSELTLVRVKVAEAGYYTMRAFHEDAEAQLSFQLQVNVPVRVL
ELSESHPASGEQTVRCRGRGMPQPHLTWSTCSDLKRCPRELPPTPLGNSSEEESQLETNV
TYWPEDQEFEVVSTLRLRRVDQPLSVRCTLHNLLGHDMQEVTVVPHSLPFKVVVISAILA
LVVLTIISLIILIMLWQKKPRYEIRWKVIESVSSDGHEYIYVDPMQLPYDSTWELPRDQL
VLGRTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGP
HLNVVNLLGACTKGGPIYIITEYCRYGDLVDYLHRNKHTFLQLCSDKRRPPSAELYSNAL
PAGLPLPSHVSLPGESDGGYMDMSKDESVDYVPMLDMKGGVKYADIESSSYMAPYDNYVP
TAPERTCRATLINESPVLSYTDLVGFSYQVANGMEFLASKNCVHRDLAARNVLICEGKLV
KICDFGLARDIMRDSNYISKGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLG
GTPYPELPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPFSQLVLLLER
LLGEGYKKKYQQVDEEFLRSDHPAVLRSQARLPGFPGLRSPLDTSSVLYTAVQPNEGDND
YIIPLPDPKPEVADGPLESSPSLASSTLNEVNTSSTISCDSPLEPQEEPEPEPEPQPEPQ
VVPEPPLDSSCPGPRAEAEDSFL
NT seq 3312 nt   +upstreamnt  +downstreamnt
atgcaggttccaggcaccatgccagctcctgtcctcaaaggccaggcactgtggctgccg
ctgctgttgatgctgagcccacaggcctccggtggcctggtcatcacacccccggggccg
gagcttgtccttaatatctctagcaccttcgttctgacctgctcgggtccagctccggtg
gtatgggaacggttgtcccaagagcccctgcagaaaatggccaggacccaggatggcacc
ttctccagcacactgacactgaccaatgtcactgggctagacacgggagagtacttttgc
acctacaaaggctcccatgggctggagcctgatgggcgaaaacggctctatatctttgtg
ccagatcccactatgggctttctcccggttgaccctgaggaactcttcatctttctcacg
gaaataacggagatcacaattccatgccgagtgacggatccaagactggtggtgacacta
cacgagaagaaagtggatatcccactgcccatcccctatgaccaccaacgtggcttctct
ggtaccttcgaggacaagacttatgtctgcaagaccaccatcggggacaaggaagtggat
tctgaagcctactatgtctacagcctccaggtgtcatccatcaacgtctccgtgaatgca
gtgcagactgtggtccgccagggtgagaacatcaccatcatgtgcatcgtgaccggaaat
gaggtggttaactttgaatggacatacccacgcatggagagtgggcggctggtggagcca
gtgactgacttcctcttcaatgtgccctcccacatacgctccattctgcacatccctagt
gctgagcttggcgattcagggacctacatctgcaatgtatcagaaagtgtgaatgaccat
cgagatgaaaagtccatcaacgtcaccgtggttgagagcggctacgtgcggctgctgggg
gagctggacgccgtacagttcgcggagctgcaccgcagccgggctctgcaggtcgtgttc
gaggcctacccgccgcctactgtcgtgtggttcaaggacaaccgcacgctaggcgactcc
agcgcaggcgagatcgccttgtccacacgcaacgtgtctgagacccggtacgtgtcagaa
ctgacgttggtgcgggtcaaggtggccgaggctggctactacaccatgcgggccttccat
gaggatgccgaggcccagctctccttccagctgcaggtcaacgtgcctgtccgcgtgctg
gagctgagtgaaagccaccctgccagcggggagcagacagtccgatgtcgcggccggggc
atgccccagccacacctcacctggtctacctgcagcgacctcaaaagatgtcctcgcgag
ctgccacccacgccgctagggaacagttcagaggaggagagccagctggagactaacgtg
acatactggcctgaggatcaggagttcgaggtggtgagcacgctgcgcctgcgccgtgtg
gatcagccgctgtcggtgcgctgcactctgcacaacctgctgggacacgacatgcaggag
gtcaccgtggtgccacattctctgcccttcaaggtggtggtgatctcggccatcctggcc
ttggtggttctcacaatcatctccctcatcatcctcatcatgctctggcaaaagaagcca
cgttatgagatccgatggaaggtgattgaatccgtgagctccgatggccatgagtacatc
tacgtggaccctatgcagctgccctacgactccacctgggagctgccgagggaccagctc
gtgcttggacgtacgctcggctctggggcctttgggcaggtggtggaggcgacggctcac
ggcctaagccattcgcaggccacgatgaaagtggcagtcaagatgctgaaatccacagcc
cgcagcagcgagaagcaggccctcatgtcagagctgaagatcatgagtcacctcgggccc
catctaaatgtggtcaacttgctgggggcctgcaccaaaggaggacccatctacatcatc
accgagtactgccgctacggggacctggtggactaccttcaccgcaacaagcacaccttc
ctgcagctctgctccgacaagcgccgcccgcccagcgccgagctctacagcaacgccctg
cccgcggggctccctctgcccagccacgtgtctctgcctggggagagtgacgggggctac
atggacatgagcaaggacgagtcagtggattacgtgcccatgctggacatgaaaggaggc
gtcaaatatgcagacattgagtcctccagctacatggccccttatgacaactacgtcccc
actgctcccgagaggacctgtcgggcaactctgatcaatgagtccccagtgcttagctac
acggatctcgtgggcttcagctaccaggtggccaatggcatggagttcctggcctccaag
aactgtgtccaccgagatctggcagccagaaacgtgctcatctgtgagggcaagctggtc
aagatatgtgactttggcctggctcgtgacatcatgagagactcgaactatatctccaaa
ggcagcaccttcctgcctctgaagtggatggctcccgagagcatcttcaacagcctctat
accaccctgagcgacgtgtggtccttcgggatcctgctctgggagatcttcaccctgggt
ggcacaccttacccagagctgcccatgaacgaacagttctataatgccatcaagcggggc
taccgcatggctcagcctgcccacgcctctgacgagatttatgagatcatgcagaagtgc
tgggaagagaagtttgagatccggcctcccttctcccagctggtgctgcttctcgagagg
ctgctgggtgaggggtacaaaaagaagtaccagcaggtggatgaggagtttctgaggagc
gaccacccagcagtccttcggtcccaagctcgcttgcctggcttccctggcctccgatcc
cctctggacaccagctctgtcctgtacactgctgtgcagcccaacgagggtgacaacgac
tacatcatccccctgccggaccccaagcctgaggttgctgacggcccactggagagttct
cccagccttgccagctccaccctgaatgaagtcaacacctcctctaccatctcctgtgac
agccccctggaaccccaagaggagccagaaccagagccagagccccagcccgagccccag
gtggtgccggagccaccgctggattcaagctgccctgggcctcgggctgaggcagaggac
agcttcctgtag

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (19)   
   KEGG PATHWAY (19)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (8)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (8)   
   RefSeq(nuc) (6)   
   GenBank (1)   
   EMBL (1)   
Protein domain (10)   
   Pfam (10)   
All databases (64)   

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