KEGG   Canis lupus familiaris (dog): 448807
Entry
448807            CDS       T01007                                 
Symbol
TLR2
Name
(RefSeq) toll-like receptor 2 precursor
  KO
K10159  toll-like receptor 2
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04145  Phagosome
cfa04151  PI3K-Akt signaling pathway
cfa04613  Neutrophil extracellular trap formation
cfa04620  Toll-like receptor signaling pathway
cfa05132  Salmonella infection
cfa05134  Legionellosis
cfa05140  Leishmaniasis
cfa05142  Chagas disease
cfa05144  Malaria
cfa05145  Toxoplasmosis
cfa05146  Amoebiasis
cfa05152  Tuberculosis
cfa05161  Hepatitis B
cfa05162  Measles
cfa05168  Herpes simplex virus 1 infection
cfa05169  Epstein-Barr virus infection
cfa05170  Human immunodeficiency virus 1 infection
cfa05171  Coronavirus disease - COVID-19
cfa05205  Proteoglycans in cancer
cfa05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
cfa05321  Inflammatory bowel disease
cfa05323  Rheumatoid arthritis
cfa05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    448807 (TLR2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    448807 (TLR2)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    448807 (TLR2)
   04620 Toll-like receptor signaling pathway
    448807 (TLR2)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    448807 (TLR2)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    448807 (TLR2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    448807 (TLR2)
   05161 Hepatitis B
    448807 (TLR2)
   05171 Coronavirus disease - COVID-19
    448807 (TLR2)
   05162 Measles
    448807 (TLR2)
   05168 Herpes simplex virus 1 infection
    448807 (TLR2)
   05169 Epstein-Barr virus infection
    448807 (TLR2)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    448807 (TLR2)
   05134 Legionellosis
    448807 (TLR2)
   05152 Tuberculosis
    448807 (TLR2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    448807 (TLR2)
   05144 Malaria
    448807 (TLR2)
   05145 Toxoplasmosis
    448807 (TLR2)
   05140 Leishmaniasis
    448807 (TLR2)
   05142 Chagas disease
    448807 (TLR2)
  09163 Immune disease
   05323 Rheumatoid arthritis
    448807 (TLR2)
   05321 Inflammatory bowel disease
    448807 (TLR2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    448807 (TLR2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cfa04131]
    448807 (TLR2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:cfa04147]
    448807 (TLR2)
   04054 Pattern recognition receptors [BR:cfa04054]
    448807 (TLR2)
   04090 CD molecules [BR:cfa04090]
    448807 (TLR2)
   00536 Glycosaminoglycan binding proteins [BR:cfa00536]
    448807 (TLR2)
Membrane trafficking [BR:cfa04131]
 Endocytosis
  Phagocytosis
   Toll-like receptors
    448807 (TLR2)
Exosome [BR:cfa04147]
 Exosomal proteins
  Exosomal proteins of breast milk
   448807 (TLR2)
Pattern recognition receptors [BR:cfa04054]
 Membrane-bound pattern recognition receptors
  Toll-like receptors
   448807 (TLR2)
CD molecules [BR:cfa04090]
 Proteins
  448807 (TLR2)
Glycosaminoglycan binding proteins [BR:cfa00536]
 Hyaluronan
  Cell surface receptors
   448807 (TLR2)
SSDB
Motif
Pfam: LRR_8 LRR_4 TIR TIR_2 LRR_5 LRR_1 LRR_9 TANGO2
Other DBs
NCBI-GeneID: 448807
NCBI-ProteinID: NP_001005264
Ensembl: ENSCAFG00000008351
VGNC: 59443
UniProt: C0IRA0
Position
15:51808717..51811083
AA seq 785 aa
MSRVLWTLWVLGAVTNLSKEEAPDQSSSLSCDPTGVCDGRSRSLNSMPSGLTAAVRSLDL
SNNEITYIGNSDLRDCVNLKALRLESNGINTIEEESFFSLWSLEHLDLSYNLLSNLSSSW
FRPLSSLKFLNLLGNPYKSLGETPLFSQLTNLRILKVGNIYSFTEIQDKDFAGLTFLEEL
EIDASNLQRYEPKSLKSIQSISYLALRMKQPVLLVEIFVDLSSSLKHLELRDTHLDTFHF
SEASINETHTLVKKWTFRNVKVTDRSFTEVVRLLNYVSGVLEVEFEDCTLYGLGDFDIPD
VDKIKNIGQIETLTVRRLHIPHFYSFYDMSSIYSLTEDVKRITVESSKVFLVPCSLSQHL
KSLEYLDLSDNLVVEEYLRNSACQHAWPLLQTLILRQNRLKSLEKTGETLLTLKNLVNLD
ISKNNYLSMPETCQWPEKLKCLNLSDTRMQSITRCIPQTLEILDVSNNNLESFSLILPQL
KELSISRNKLKTLPDASFLPTLQIMRISRNTINAFSKEQLDSFHRLQTLEAGGNNFLCSC
EFLSFTQEQQALAGLLVGWPEDYLCHSPSYVRGQRVGTARLPASECHRTALVAAVCCVLL
LLVLLTAGACHHFHGLWYLRMLWAWLQAKRKPRKAPSRDVCYDAFVSYSEHDSYWVENLL
VQKLEHFNPPFKLCLHKRDFIPGKWIIDNIIDSIEKSHKTIFVLSENFVKSEWCKYELDF
SHFRLFDENNDAAILILLEPIEKKAIPQRFCKLRKIMNTKTYLEWPTDDAQQEGFWLNLR
TAIKS
NT seq 2358 nt   +upstreamnt  +downstreamnt
atgtcacgtgttttgtggacattgtgggttttgggggctgtaaccaacctctccaaggaa
gaggcccctgaccagtcttcttctctgtcctgtgaccccactggtgtctgcgatggccgc
tccagatctttgaactccatgccctcagggctcacagcagctgtgagaagccttgacctc
tccaacaatgagatcacctacattggcaacagtgaccttcgggattgtgtgaacctcaag
gctctgaggctggagtctaatggaattaacacaatagaggaagaatcttttttttccctg
tggagtcttgaacatttggacttatcttataacctcttatctaacttatcatcctcctgg
ttcaggcccctttcttcattgaagttcttaaacctactgggaaatccttacaaatcactt
ggggaaacacctcttttttctcagctcacaaatctaagaattctgaaagtaggaaatatc
tacagcttcactgagattcaggataaggattttgctgggctaacctttcttgaggaactg
gagatcgatgcttcaaatctccagaggtatgagccaaagagtttgaaatcgattcagagc
atcagctatctggccctccgtatgaagcagcctgttttactggtggagatttttgtagat
ctttccagttccttgaaacatttagaactgagagatactcatttggacactttccacttt
tcagaggcatccatcaatgaaacacatacgttggttaaaaagtggacatttagaaatgtg
aaagtcaccgatagaagttttactgaggttgtgagactgttgaattatgtttctggagtg
ttagaagtagagtttgaggactgtaccctttatgggctcggtgattttgacatacctgat
gtggacaaaattaaaaatataggtcagatagagacactaacagtacggaggttgcatatt
ccacacttttactcattttacgatatgagtagtatatattcacttacagaagatgttaaa
agaatcacagtagaaagcagtaaggtctttctggttccttgctcactttcacaacattta
aaatccctagaatatttggatctcagcgacaatttagtggttgaagaatacttgagaaac
tcagcctgtcagcatgcttggcccctcctgcaaaccttaattttaaggcaaaatcgtttg
aaatccttagagaaaactggagaaactttgcttactttgaaaaacctggtgaaccttgat
attagtaagaataattatctttctatgcctgaaacttgtcagtggccagaaaagctgaaa
tgtttgaacttatccgacacaagaatgcaaagtataacccgttgcatccctcagacactg
gaaattttagatgttagcaataataatctcgagtcattttccctgattttgccacaactt
aaagaactttctatttccagaaataagttgaagactctaccagatgcctccttcttaccc
accttacaaattatgagaatcagcagaaacacaataaacgctttctcgaaggagcaactg
gattcctttcacaggctgcagaccctggaggccggtggcaacaacttcctttgctcctgt
gaattcctgtctttcactcaggagcagcaggccctggccgggctcctggtcggctggcca
gaggactacctgtgccactccccctcctacgtgcggggccagcgggttgggaccgcccgg
ctcccggcttctgagtgccaccggacagctctggtggccgccgtgtgctgtgtcttgctc
ctgctggtcctgctcacggcgggggcgtgccaccatttccacgggctgtggtacctgaga
atgctgtgggcctggctccaggccaaaaggaagcccaggaaagccccctccagggacgtc
tgttatgacgcctttgtgtcttacagtgagcatgattcctactgggtggagaaccttctg
gtccagaagctggagcacttcaatcccccgttcaagttgtgccttcacaagcgggacttt
attcccggcaagtggattattgacaatatcattgactccatcgagaagagccacaaaacc
atctttgtgctttctgaaaacttcgtgaaaagcgagtggtgcaagtacgagctggacttc
tcccattttcgcctctttgatgagaacaacgatgctgccatcctcattcttctggagccc
attgagaaaaaggccatcccccagcgattctgtaagctgcggaagataatgaacaccaag
acgtacctggagtggcccaccgatgatgctcagcaggaagggttttggttaaatttgaga
acagcaataaaatcctag

  All links  
Ontology (6)   
   KEGG BRITE (6)   
Pathway (23)   
   KEGG PATHWAY (23)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (6)   
   UniProt (1)   
   RefSeq(pep) (5)   
DNA sequence (11)   
   RefSeq(nuc) (5)   
   GenBank (3)   
   EMBL (3)   
Protein domain (8)   
   Pfam (8)   
All databases (76)   

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