KEGG   Canis lupus familiaris (dog): 474503
Entry
474503            CDS       T01007                                 
Symbol
ATF4
Name
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
  KO
K04374  cyclic AMP-dependent transcription factor ATF-4
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04010  MAPK signaling pathway
cfa04022  cGMP-PKG signaling pathway
cfa04137  Mitophagy - animal
cfa04141  Protein processing in endoplasmic reticulum
cfa04151  PI3K-Akt signaling pathway
cfa04210  Apoptosis
cfa04211  Longevity regulating pathway
cfa04261  Adrenergic signaling in cardiomyocytes
cfa04668  TNF signaling pathway
cfa04720  Long-term potentiation
cfa04722  Neurotrophin signaling pathway
cfa04725  Cholinergic synapse
cfa04728  Dopaminergic synapse
cfa04911  Insulin secretion
cfa04912  GnRH signaling pathway
cfa04915  Estrogen signaling pathway
cfa04918  Thyroid hormone synthesis
cfa04922  Glucagon signaling pathway
cfa04925  Aldosterone synthesis and secretion
cfa04926  Relaxin signaling pathway
cfa04927  Cortisol synthesis and secretion
cfa04928  Parathyroid hormone synthesis, secretion and action
cfa04932  Non-alcoholic fatty liver disease
cfa04934  Cushing syndrome
cfa04935  Growth hormone synthesis, secretion and action
cfa05010  Alzheimer disease
cfa05012  Parkinson disease
cfa05014  Amyotrophic lateral sclerosis
cfa05020  Prion disease
cfa05022  Pathways of neurodegeneration - multiple diseases
cfa05030  Cocaine addiction
cfa05031  Amphetamine addiction
cfa05034  Alcoholism
cfa05161  Hepatitis B
cfa05163  Human cytomegalovirus infection
cfa05166  Human T-cell leukemia virus 1 infection
cfa05203  Viral carcinogenesis
cfa05207  Chemical carcinogenesis - receptor activation
cfa05215  Prostate cancer
cfa05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    474503 (ATF4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    474503 (ATF4)
   04668 TNF signaling pathway
    474503 (ATF4)
   04022 cGMP-PKG signaling pathway
    474503 (ATF4)
   04151 PI3K-Akt signaling pathway
    474503 (ATF4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    474503 (ATF4)
  09143 Cell growth and death
   04210 Apoptosis
    474503 (ATF4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    474503 (ATF4)
   04922 Glucagon signaling pathway
    474503 (ATF4)
   04912 GnRH signaling pathway
    474503 (ATF4)
   04915 Estrogen signaling pathway
    474503 (ATF4)
   04926 Relaxin signaling pathway
    474503 (ATF4)
   04935 Growth hormone synthesis, secretion and action
    474503 (ATF4)
   04918 Thyroid hormone synthesis
    474503 (ATF4)
   04928 Parathyroid hormone synthesis, secretion and action
    474503 (ATF4)
   04925 Aldosterone synthesis and secretion
    474503 (ATF4)
   04927 Cortisol synthesis and secretion
    474503 (ATF4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    474503 (ATF4)
  09156 Nervous system
   04725 Cholinergic synapse
    474503 (ATF4)
   04728 Dopaminergic synapse
    474503 (ATF4)
   04720 Long-term potentiation
    474503 (ATF4)
   04722 Neurotrophin signaling pathway
    474503 (ATF4)
  09149 Aging
   04211 Longevity regulating pathway
    474503 (ATF4)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    474503 (ATF4)
   05203 Viral carcinogenesis
    474503 (ATF4)
  09162 Cancer: specific types
   05215 Prostate cancer
    474503 (ATF4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    474503 (ATF4)
   05161 Hepatitis B
    474503 (ATF4)
   05163 Human cytomegalovirus infection
    474503 (ATF4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    474503 (ATF4)
   05012 Parkinson disease
    474503 (ATF4)
   05014 Amyotrophic lateral sclerosis
    474503 (ATF4)
   05020 Prion disease
    474503 (ATF4)
   05022 Pathways of neurodegeneration - multiple diseases
    474503 (ATF4)
  09165 Substance dependence
   05030 Cocaine addiction
    474503 (ATF4)
   05031 Amphetamine addiction
    474503 (ATF4)
   05034 Alcoholism
    474503 (ATF4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    474503 (ATF4)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    474503 (ATF4)
   04934 Cushing syndrome
    474503 (ATF4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:cfa03000]
    474503 (ATF4)
Transcription factors [BR:cfa03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    474503 (ATF4)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 NAM-associated DUF4407 MCU Fib_alpha AAA_13 Nop53 bZIP_Maf Laminin_II
Other DBs
NCBI-GeneID: 474503
NCBI-ProteinID: XP_859677
Ensembl: ENSCAFG00000001324
VGNC: 38210
UniProt: A0A8C0NR73 A0A8I3PFQ3
Position
10:complement(25464741..25466879)
AA seq 350 aa
MAEMSFLSSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSE
WLALDGLVSASDNGKEDAFSGTDWMVEKMDLKEFDFDTLFSIDDLETMPDELLATLDDTC
DLFDPLVQETNKEPPQIVNPIGHLPESLPKTDQIAPFTFLQPLPLSPGALSSTPDHSFSL
ELGSEVDISEGDRKSDSTAYITVIPQCIKEEDAPSDNDSGICMSPESYLGSPQHSPSTSR
GSPNRSLLSPGSLCGSARPKPYDPPGEKTAKVKVEKLDKKLKKMEQNKTAATRYRQKKRA
EQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKAREKKRVP
NT seq 1053 nt   +upstreamnt  +downstreamnt
atggccgagatgagtttcctgagcagcgaggtgttggtgggggacttgatgtcccccttc
gaccagtcgggtttgggggctgaggaaagcctaggtctcttagacgactacctggaggtg
gccaagcacttcaaacctcatgggttctccagcgacaaggctaaggcgggctcctccgaa
tggctggctttggatgggttggtcagtgcctcagacaacggcaaggaggatgccttctcc
gggacagattggatggtggagaaaatggatctgaaggagtttgattttgacactctgttc
agtatagatgacctggaaaccatgccagatgagcttttggccacgttggatgacacgtgt
gatctctttgaccccctagtccaggagactaataaggagccccctcagatcgtgaaccca
attggccatctcccagaaagtttaccaaaaacagaccagattgccccctttacctttctg
caaccacttccactctccccaggggccctgtcctccactccagatcattcttttagttta
gagctaggcagtgaagtggatatctctgaaggagatagaaagtcagattctactgcttac
attaccgtgatccctcagtgcataaaggaggaagatgccccctcagataatgacagtggc
atctgtatgagtcctgagtcctatcttgggtccccccagcatagcccctctacctccagg
ggctctccaaataggagcctgctgtctccaggttccctctgtggttctgcccgccccaaa
ccctatgaccctcctggagagaagaccgcaaaagtaaaggttgagaaactagataagaaa
ctgaaaaaaatggagcagaacaagacagcagccactaggtaccgccagaagaagagggca
gagcaggaagccctcactggtgagtgtaaagaactggaaaagaagaacgaggctctgaag
gagagggcagattctttagctaaggagatccagtatctgaaagatttgatagaggaggtc
agaaaggccagggagaagaaaagggtcccctag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (40)   
   KEGG PATHWAY (40)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (7)   
   UniProt (2)   
   RefSeq(pep) (5)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (10)   
   Pfam (10)   
All databases (77)   

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