KEGG   Canis lupus familiaris (dog): 476198
Entry
476198            CDS       T01007                                 
Symbol
ME2
Name
(RefSeq) NAD-dependent malic enzyme, mitochondrial isoform X1
  KO
K00027  malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa00620  Pyruvate metabolism
cfa01200  Carbon metabolism
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    476198 (ME2)
Enzymes [BR:cfa01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.38  malate dehydrogenase (oxaloacetate-decarboxylating)
     476198 (ME2)
SSDB
Motif
Pfam: Malic_M malic
Other DBs
NCBI-GeneID: 476198
NCBI-ProteinID: XP_005615454
Ensembl: ENSCAFG00000000168
VGNC: 43110
UniProt: A0A8C0SEL5 A0A8I3MHQ2
Position
1:complement(24972260..25020810)
AA seq 584 aa
MLSRLRIVAVPSTLACRHIHIKEKGKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIET
QDIQALRFHKNVKKMNGPLEKYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLAC
SQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVKAVVVTDGERILGLGDLGVYGMGIP
VGKLCLYTACAGIRPDRCLPVCIDVGTDNPALLKDPFYMGLYQKRDRSQRYDDLIDEFMK
AITDRYGQNTLIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTAAVALAGLLAAQKVIGK
SFSEHKILFLGAGEAALGIANLIVMAMVENGLSEEEAQKKIWMVDKFGLLFKGRKAKIEN
HQEPFAHSAPGIIPDTFEDAVNILRPSAIIGVAGAGRLFTPGVIKAMADINERPVIFALS
NPTAMAECTAEEAYTLTEGRCLFASGSPFEPVKLSDGQLFTPGQGNNVYIFPGVALAVIL
CNTRHISDHVFLEAAKALANQLTDKELAQGRLYPPLADIQEVSINIAIKVTEYLYANKMA
FRYPEPEDKAKYIRERIWRSEYDSLLPDVYDWPESALSPPLITE
NT seq 1755 nt   +upstreamnt  +downstreamnt
atgttgtcccggttaagaatagttgctgttccttccaccctggcatgtcgtcacatacac
ataaaagagaaaggcaagccgctcatgctaaacccaagaacaaacaagggaatggcattt
acattacaagagcgacaaatgcttggtcttcaaggacttctacctcccaaaatagagaca
caggatattcaagctttacgatttcataaaaacgtgaaaaaaatgaatggccctttggaa
aagtacatctatataatgggaatacaagaaagaaatgaaaagctgttttatagaattctg
caagatgatatcgaaagtctgatgccgattgtgtacacgccaacagtgggtcttgcctgt
tcccagtatggacacatctttagaagacctaagggattatttatttcaatctcagacaga
ggtcatgttagatcaattgtggataactggccagaaaatcatgttaaggctgttgtggtg
actgatggagagagaattctgggtctcggagatctgggtgtctatggaatgggaatccca
gtaggaaaactttgtttgtatacagcttgtgcaggaatacggcctgatagatgcctgcct
gtgtgtattgatgtaggaacggataatccagcactcttaaaagatccattttacatgggc
ttatatcagaaaagagatcgatcacaacgttatgatgacctgattgatgagtttatgaaa
gccattactgacagatatggacagaacacacttattcagtttgaagactttggaaatcat
aatgcattcaggttcttgagaaaatatcgagaaaagtattgcaccttcaatgatgatatt
caaggaacagctgcagtagctctagcaggtcttcttgcagcacaaaaagttattggtaaa
tcattctcagaacacaaaatcttattccttggagcaggagaggctgctcttggaattgca
aatctcatagttatggctatggtagaaaatggcctctcagaagaagaggcacaaaagaaa
atttggatggttgacaagtttggtttattatttaaggggcggaaagctaaaatagagaat
catcaggaaccatttgctcattcagccccagggatcatacctgatacttttgaagatgca
gtcaatatactcaggccttcagctataattggagttgcaggagccggccgactattcact
cccggtgtaatcaaagccatggctgatatcaatgaaagacctgtaatatttgcattaagc
aatcctacagcgatggctgagtgcactgctgaggaagcgtatacacttacagagggaaga
tgtttgtttgccagtggcagtccatttgagccagtgaaactcagtgatgggcagctcttt
acaccaggccaaggaaacaatgtgtatatttttccaggcgtggctttagctgttattctc
tgtaacacccggcatattagtgaccatgttttcctagaagctgcaaaggcactggcaaat
caattgacagataaagagctagctcaagggagactttacccaccacttgctgatattcag
gaagtttctattaacattgctattaaagtcacagagtacctgtatgctaacaaaatggct
ttccggtacccggaacctgaggacaaggccaaatacattagagaaagaatatggcgaagt
gaatatgattccctgctgccggatgtgtatgactggcccgagtctgcgttaagccctccc
ctgataacggaatag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (22)   
   UniProt (2)   
   RefSeq(pep) (20)   
DNA sequence (20)   
   RefSeq(nuc) (20)   
Protein domain (2)   
   Pfam (2)   
All databases (66)   

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