KEGG   Canis lupus familiaris (dog): 477886
Entry
477886            CDS       T01007                                 
Symbol
LYN
Name
(RefSeq) tyrosine-protein kinase Lyn isoform X2
  KO
K05854  tyrosine-protein kinase Lyn [EC:2.7.10.2]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04062  Chemokine signaling pathway
cfa04064  NF-kappa B signaling pathway
cfa04611  Platelet activation
cfa04662  B cell receptor signaling pathway
cfa04664  Fc epsilon RI signaling pathway
cfa04666  Fc gamma R-mediated phagocytosis
cfa04730  Long-term depression
cfa05167  Kaposi sarcoma-associated herpesvirus infection
cfa05169  Epstein-Barr virus infection
cfa05203  Viral carcinogenesis
cfa05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    477886 (LYN)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    477886 (LYN)
   04662 B cell receptor signaling pathway
    477886 (LYN)
   04664 Fc epsilon RI signaling pathway
    477886 (LYN)
   04666 Fc gamma R-mediated phagocytosis
    477886 (LYN)
   04062 Chemokine signaling pathway
    477886 (LYN)
  09156 Nervous system
   04730 Long-term depression
    477886 (LYN)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    477886 (LYN)
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    477886 (LYN)
   05169 Epstein-Barr virus infection
    477886 (LYN)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    477886 (LYN)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cfa01001]
    477886 (LYN)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cfa04131]
    477886 (LYN)
Enzymes [BR:cfa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     477886 (LYN)
Protein kinases [BR:cfa01001]
 Non-receptor tyrosine kinases
  SRC family
   477886 (LYN)
Membrane trafficking [BR:cfa04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    477886 (LYN)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_2 SH3_9 SH3_3 ABC1 Haspin_kinase
Other DBs
NCBI-GeneID: 477886
NCBI-ProteinID: XP_005638056
Ensembl: ENSCAFG00000007034
VGNC: 42882
UniProt: A0A8C0TT90 A0A8I3SAH4
Position
29:7646390..7761519
AA seq 491 aa
MGCIKSKRKDNLNDEGIDLKTQPVSESQLLPGQRFQTKDPEEQGDIVVALYPYDGIHPDD
LSFKKGEKMKVLEELGEWWKAKSLSTKREGFIPSNYVAKVNTLETEEWFFKDITRKDAER
QLLAPGNSAGAFLIRESETLKGSYSLSVRDYDPVHGDVIKHYKIRSLDNGGYYISPRITF
PCISDMIKHYQKQSDGLCRRLEKACISPKPQKPWDKDAWEIPRESIKLVKRLGAGQFGEV
WMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKLVRLYAVVTREEPIYIITEY
MAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVSESLMC
KIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGK
IPYPGRTNADVMTALSQGYRMPRMENCPDELYDIMKMCWKEKAEERPTFDYLQSVLDDFY
TATEGQYQQQP
NT seq 1476 nt   +upstreamnt  +downstreamnt
atgggatgtataaaatcaaaaaggaaagacaatctgaatgacgaaggaatagatttgaag
actcaaccagtttcagaatctcagcttttaccaggacagaggtttcaaactaaagatcca
gaggagcaaggagacatcgtggtagccttgtacccctatgatggcatccatccagatgac
ttgtctttcaagaaaggagagaaaatgaaagtcctggaggaacttggagaatggtggaaa
gctaaatctctttcaacaaagagagaagggttcatccccagcaactatgtagccaaagtg
aacacgttggaaacagaagagtggtttttcaaggatataaccaggaaagatgcagaacgg
cagcttctggcgccagggaacagtgctggagcttttcttatcagagaaagcgaaacatta
aaaggaagctactctctttccgtcagagattatgaccctgtgcatggtgatgttattaag
cactacaaaattagaagtctggacaatgggggatattacatctctccacgaatcactttt
ccttgtatcagcgacatgattaaacattaccaaaagcagtcagatggcttgtgcagaaga
ttggagaaggcatgtattagccccaaaccacaaaagccatgggacaaagatgcctgggaa
atcccacgggaatccatcaagttggtgaaaaggcttggtgccgggcagttcggggaagtc
tggatgggttactataacaatagtaccaaagtggctgtaaaaaccctgaaaccaggcact
atgtctgtgcaagcattcctggaggaagcaaacctcatgaagacccttcaacatgacaag
ctggtgaggctgtatgccgtggtcaccagagaggagcctatctacatcatcaccgagtac
atggccaagggcagtttgctggatttcctgaagagcgatgagggggggaaagtgctgctt
ccaaagctaatcgacttttctgcccagattgcagagggaatggcatacatcgagagaaag
aactacatccaccgagatctacgagcagcaaacgttctggtttctgagtcactcatgtgc
aaaattgcagattttggtcttgctcgagtcatcgaagataatgaatacacagcaagagaa
ggtgccaaattccccattaagtggacagctccagaagcaatcaactttggatgtttcacc
attaagtctgatgtgtggtcctttggcattctcctgtatgaaatcgtcacctatgggaag
attccttacccagggagaactaatgccgatgtgatgaccgccctgtcgcagggctacagg
atgccccgcatggagaactgcccagacgagctctacgacatcatgaaaatgtgctggaag
gagaaagcagaagagaggccaacgtttgattacctgcagagtgtcctggatgatttctac
actgccacagaagggcagtatcagcagcagccttaa

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (11)   
   KEGG PATHWAY (11)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (22)   
   UniProt (2)   
   RefSeq(pep) (20)   
DNA sequence (20)   
   RefSeq(nuc) (20)   
Protein domain (9)   
   Pfam (9)   
All databases (77)   

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