KEGG   Canis lupus familiaris (dog): 478051
Entry
478051            CDS       T01007                                 
Symbol
LARS1
Name
(RefSeq) leucine--tRNA ligase, cytoplasmic isoform X2
  KO
K01869  leucyl-tRNA synthetase [EC:6.1.1.4]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa00970  Aminoacyl-tRNA biosynthesis
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09120 Genetic Information Processing
  09122 Translation
   00970 Aminoacyl-tRNA biosynthesis
    478051 (LARS1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes [BR:cfa01007]
    478051 (LARS1)
  09182 Protein families: genetic information processing
   03016 Transfer RNA biogenesis [BR:cfa03016]
    478051 (LARS1)
   03029 Mitochondrial biogenesis [BR:cfa03029]
    478051 (LARS1)
Enzymes [BR:cfa01000]
 6. Ligases
  6.1  Forming carbon-oxygen bonds
   6.1.1  Ligases forming aminoacyl-tRNA and related compounds
    6.1.1.4  leucine---tRNA ligase
     478051 (LARS1)
Amino acid related enzymes [BR:cfa01007]
 Aminoacyl-tRNA synthetase
  Class I (U)
   478051 (LARS1)
Transfer RNA biogenesis [BR:cfa03016]
 Eukaryotic type
  Aminoacyl-tRNA synthetases (AARSs)
   Multi-aminoacyl-tRNA synthetase complex (MSC)
    478051 (LARS1)
 Prokaryotic type
    478051 (LARS1)
Mitochondrial biogenesis [BR:cfa03029]
 Mitochondrial DNA transcription, translation, and replication factors
  Mitochondrial transcription and translation factors
   Other mitochondrial DNA transcription and translation factors
    478051 (LARS1)
SSDB
Motif
Pfam: tRNA-synt_1 Anticodon_1 tRNA-synt_1g tRNA-synt_1e
Other DBs
NCBI-GeneID: 478051
NCBI-ProteinID: XP_013963711
Ensembl: ENSCAFG00000006431
VGNC: 42592
Position
2:complement(37588723..37663534)
AA seq 1175 aa
MERKGTAKVDFLKKIEKEIQQKWATEKVFEVDASNLENQTGKGKYFVTFPYPYMNGRLHL
GHTFSLSKCEFAVGYQRLKGKTCLFPFGLHCTGMPIKACADKLKREIELYGCPPDFPDEE
EEEEEIPVKTEEVIIKDKAKGKKSKAAAKAGSSKYQWGIMKSLGLSDEEIVKFSEAEHWL
DYFPPLAIQDLKRMGLKVDWRRSFITTDVNPYYDSFVRWQFLTLRERNKIKFGKRYTIYS
PKDGQPCMDHDRQTGEGVGPQEYTLIKLKVLEPYPSKLSGLKGKNIFLVAATLRPETMFG
QTNCWVRPDMKYIGFETVNGDIFICTQRAARNMSYQGFTKHNGVVPVVKELMGEEILGAS
LSAPLTSYTVVYVLPMLTIKEDKGTGVVTSVPSDSPDDFAALRDLKKKQALRAKYGIRDD
MVLPFEPVPIIEIPGFGNLSAVTICDDLKVQSQNDREKLAEAKEKLYLKGFYDGIMLVDG
FKGQKVQDVKKTIQKKMIDTGDAFTYMEPEKQVMSRSSDECVVALCDQWYLDYGEENWKK
QTSQCLKGLETFCEETRRNFEATLGWLQEHACSRTYGLGTRLPWDEQWLIESLSDSTIYM
AFYTVAHLLQGGNLRGQTESPLGIRPQQMTREVWDYVFFKEAPFPKTQIPKEKLDQLKQE
FEFWYPVDLRVSGKDLVPNHLSYYLYNHVAMWPEQSDKWPAAVRANGHLLLNSEKMSKST
GNFLTLTQAIDKFSADGMRLALADAGDTVEDANFVEAMADAGILRLYTWVEWVKEMVANW
DSLRSGPASTFNDRVFASEMNAGIIKTDQNYEKMMFKEALKTGFFEFQAAKDKYRELAIE
GMHRDLVFRFIEVQTLLLAPFCPHLCEHIWTLLGKPDSIMNASWPLAGPVDEALIRSSQY
LMEVAHDLRLRLKNYMMPAKGKKTDKQPPQKPSHCTIYVAKNYPSWQHTTLSVLRNHFEA
NSGKLPDNKVIASELGNLPELKKYMKKVMPFVAMIKENLEKMGPRVLDLQLEFDEQAVLM
ENLVYLTNSLELEHIEVKFASEAEDKVREDCCPGKPLNVFRTEPGVSVSLVNPQPSNGHF
TTKIEIRQGDNRDSIIRRLMKMDRGIKDLSKVKLMRFDDPLLGPRRVPVLGKEHTGKTPI
SEHAVFHVDLMSKKIHLTENGLGADIGDTIIYLVH
NT seq 3528 nt   +upstreamnt  +downstreamnt
atggaaagaaaaggaacagccaaagtagactttttgaagaagattgagaaggaaatccaa
cagaaatgggctactgagaaagtatttgaggttgatgcatctaatttagagaaccagact
ggcaagggcaagtactttgtaaccttcccatatccgtatatgaatgggcgccttcatttg
ggacacacattttctttatccaaatgtgagtttgcagtaggataccagagactgaaagga
aaaacttgtctgtttccctttggtttacactgtactggaatgcctatcaaggcatgtgct
gataagttgaaaagagaaatagagctttatggttgccctcctgattttccagatgaagaa
gaggaagaggaagaaatccctgttaaaacagaagaagtaataattaaagataaagctaaa
ggaaaaaagagtaaggctgctgctaaagctggatcttctaaatatcagtggggcattatg
aaatcccttggtctgtctgatgaagagatagttaaattttctgaagcagaacattggctt
gattatttcccaccactggctattcaggatttgaagagaatgggtttgaaggtagactgg
cgtcgttccttcatcaccactgatgttaatccttactatgattcatttgtcaggtggcag
tttttaacgttaagagaaagaaacaaaataaaatttgggaagcggtataccatttattct
ccaaaagatggacagccttgcatggatcatgacaggcaaactggagagggtgtgggacct
caggaatatactttaatcaagttgaaagtgcttgagccgtacccatccaaattaagtggc
ctgaaagggaaaaacatcttcttggtagctgctactctcagacctgagaccatgtttgga
cagaccaactgttgggttcgccctgatatgaaatacattgggtttgagacagtgaatggt
gatatattcatttgcacccaaagagctgccaggaatatgtcataccagggctttaccaaa
cacaatggagtggtgcctgttgttaaggaattaatgggagaggaaattcttggtgcatca
ctttctgcacctttaacatcttatacggtggtctatgttcttccaatgctcaccattaag
gaggataaaggtactggcgtggtcacaagtgttccttctgactcccccgatgattttgct
gccctcagagatctgaagaaaaagcaagccttacgagcaaagtatggaattagagatgac
atggtcttgccatttgagccggtgccaatcatcgaaatcccaggttttggaaatctttct
gctgtaaccatttgtgatgatttgaaagttcaaagccagaatgaccgagaaaaacttgca
gaagcaaaggagaagttatatttaaaagggttttatgatggtataatgttggtggatgga
tttaaaggacagaaggtccaagatgtaaagaagactattcagaaaaagatgattgacact
ggagatgcatttacttacatggaaccagagaaacaagttatgtccagatcttcagatgaa
tgtgttgtggcgctgtgcgaccagtggtacttggattatggagaagaaaattggaaaaaa
cagacatcccagtgcttgaaaggcctggaaacattctgtgaggagaccaggaggaatttt
gaagctaccttaggttggctacaagagcatgcctgctcaagaacttacggtttaggtact
cgtctgccgtgggatgagcagtggctgattgaatcgctctctgattccactatttacatg
gcattttacacagttgcacacctcctgcaggggggtaacttgcgtggacagacagagtct
ccacttggtatcagaccgcaacagatgaccagggaggtttgggattatgttttcttcaag
gaggctccatttcctaagactcagatcccaaaggaaaaattagatcagttaaagcaggaa
tttgagttctggtatcctgtggatctccgagtctctggaaaggatcttgttccaaatcat
ctctcatattacctttataatcatgtggcaatgtggccagaacaaagtgacaaatggcct
gctgctgtgagagcaaatggacatctcctcctcaactctgagaagatgtcaaagtccaca
ggcaacttcctcactttgacccaagctatcgacaaattttcagctgatggaatgcgtttg
gctctggctgatgctggcgacactgttgaagatgcaaactttgtggaagccatggcagat
gcaggtattctccgtctgtacacctgggtggagtgggtgaaagaaatggttgccaactgg
gacagcctaagaagtgggcctgccagcaccttcaatgatagagtttttgccagtgagatg
aatgcaggaattataaaaacagatcaaaattatgaaaagatgatgtttaaagaagccctg
aaaacagggttttttgagtttcaggctgcgaaagataaataccgtgaattggccatagaa
ggtatgcacagagaccttgtgttccgctttattgaagttcaaacacttctcttggctcca
ttctgtccacacctatgtgaacacatctggacactcctgggaaagcctgactccattatg
aatgcttcatggcctctggctggtcctgtggatgaagccttgatacgttcctcacagtat
ctcatggaagtagcacatgaccttagattgcgactcaagaactatatgatgccagctaag
gggaagaagactgacaagcaaccacctcagaaaccttcacattgcaccatctatgtggcg
aagaactatccttcttggcaacataccaccctgtcagtgctgcgtaatcactttgaggcc
aacagtggaaaattgcctgataacaaagtcattgctagtgaactgggcaatctgccagaa
ttgaagaaatatatgaagaaagtgatgccgtttgttgccatgattaaggaaaatctggag
aagatgggacctcgtgttctggatttgcagctagaatttgatgaacaggcggtgctgatg
gagaatttagtttacctgaccaattcccttgagctagaacacatagaagtcaagtttgcc
tccgaagcagaagataaagtcagggaagactgctgtcctgggaaaccacttaatgttttc
aggacagaacctggtgtgtcagtctccctagtgaatccccagccatcaaatggccacttc
acaaccaaaattgaaatcaggcaaggggataaccgcgattctataatcaggcgtttaatg
aaaatggaccgaggcatcaaagacctttctaaagtgaagctgatgagatttgatgatcca
ctgttgggacctcggcgagttcctgtcctgggaaaagagcacactgggaagactcccatt
tctgagcatgctgttttccatgtggacctcatgagcaagaaaattcatctcactgaaaat
gggctaggggcagatattggtgatacaattatctatttggttcattaa

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (20)   
   RefSeq(pep) (20)   
DNA sequence (20)   
   RefSeq(nuc) (20)   
Protein domain (4)   
   Pfam (4)   
All databases (77)   

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