KEGG   Canis lupus familiaris (dog): 478331
Entry
478331            CDS       T01007                                 
Symbol
TLN2
Name
(RefSeq) talin-2 isoform X1
  KO
K06271  talin
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04015  Rap1 signaling pathway
cfa04510  Focal adhesion
cfa04611  Platelet activation
cfa04820  Cytoskeleton in muscle cells
cfa05166  Human T-cell leukemia virus 1 infection
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    478331 (TLN2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    478331 (TLN2)
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    478331 (TLN2)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    478331 (TLN2)
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    478331 (TLN2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:cfa04147]
    478331 (TLN2)
Exosome [BR:cfa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   478331 (TLN2)
  Exosomal proteins of other cancer cells
   478331 (TLN2)
SSDB
Motif
Pfam: VBS Talin_middle I_LWEQ Talin_R4 FERM_f0 FERM_M FERM_N ACBP IRS OTU1_UBXL
Other DBs
NCBI-GeneID: 478331
NCBI-ProteinID: XP_005638534
Ensembl: ENSCAFG00000016905
VGNC: 47402
UniProt: A0A8C0MT17 A0A8I3S166
Position
30:26939212..27366590
AA seq 2542 aa
MVALSLKICVRHCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASDYGLFLSDEDPRK
GIWLEAGRTLDYYMLRNGDILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSR
IGITNYEEYSLIQETIEEKKEEGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLNWLDHSR
TFREQGVDEHETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEKACEF
GGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKRIFQEHKNCGEMSEIEAKVK
YVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVK
RWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEES
TMLEESVSPKKSTILQQQFNRTGKVEHGSVALPAVMRSGSSGPETFNVGSMPSPQQQVTV
GQMHRGHMAPLTSAQQALMGTINTSMHAVQQAQDDLSELDSLPPLGQDMASRVWVQNKVD
ESKHEIHSQVDAITAGTASVVNLTAGDPADTDYTAVGCAITTISSNLTEMSKGVKLLAAL
MDDEVGSGEDLLRAARTLAGAVSDLLKAVQPTSGEPRQTVLTAAGSIGQASGDLLRQIGE
NETDERFQDVLMSLAKAVANAAAMLVLKAKNVAQVAEDTVLQNRVIAAATQCALSTSQLV
ACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVRACQAATDDSELLKQVSAAASVVSQA
LHDLLQHVRQFASRGEPIGRYDQATDTIMCVTESIFSSMGDAGEMVRQARVLAQATSDLV
NAMRSDAEAEIDMENSKKLLAAAKLLADSTARMVEAAKGAAANPENEDQQQRLREAAEGL
RVATNAAAQNAIKKKIVNRLEVAAKQAAAAATQTIAASQNAAVSNKNPAAQQQLVQSCKA
VADHIPQLVQGVRGSQAQAEDLSAQLALIISSQNFLQPGSKMVSSAKAAVPTVSDQAAAM
QLSQCAKNLATSLAELRTASQKAHEACGPMEIDSALSTVQTLKNELQDAKMAAVESQLKP
LPGETLEKCAQDLGSTSKAVGSSMAQLLTCAAQGNEHYTGVAARETAQALKTLAQAARGV
AASTNDPAAAHAMLDSARDVMEGSAMLIQEAKQALIAPGDAESQQRLAQVAKAVSHSLNN
CVNCLPGQKDVDVALKSIGESSKKLLVDSLPPSTKPFQEAQSELNQAAADLNQSAGEVVH
ATRGQSGELAAASGKFSDDFDEFLDAGIEMAGQAQTKEDQIQVIGNLKNISMASSKLLLA
AKSLSVDPGAPNAKNLLAAAARAVTESINQLITLCTQQAPGQKECDNALRELETVKGMLD
NPNEPVSDLSYFDCIESVMENSKVLGESMAGISQNAKTGDLPAFGECVGIASKALCGLTE
AAAQAAYLVGISDPNSQAGHQGLVDPIQFARANQAIQMACQNLVDPGSSPSQVLSAATIV
AKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEDNRNKC
RIATAPLIEAVENLTAFASNPEFVSIPAQISSEGSQAQEPILVSAKTMLESSSYLIRTAR
SLAINPKDPPTWSVLAGHSHTVSDSIKSLITSIRDKAPGQRECDYSIDGINRCIRDIEQA
SLAAVSQSLATRDDISVEALQEQLTSVVQEIGHLIDPIATAARGEAAQLGHKVTQLASYF
EPLILAAVGVASKILDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAQHTHDAITEA
AQLMKEAVDDIMVTLNEAASEVGLVGGMVDAIAEAMSKLDEGTPPEPKGTFVDYQTTVVK
YSKAIAVTAQEMMTKSVTNPEELGGLASQMTSDYGHLALQGQMAAATAEPEEIGFQIRTR
VQDLGHGCIFLVQKAGALQICPTDSYTKRELIECARAVTEKVSLVLSALQAGNKGTQACI
TAATAVSGIIADLDTTIMFATAGTLNAENNETFADHRENILKTAKALVEDTKLLVSGAAS
TPDKLAQAAQSSAATITQLAEVVKLGAASLGSDDPETQVVLINAIKDVAKALSDLIGATK
GAASKPADDPSMYQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIEYMKQELTV
FQSKEVPEKTSSPEESIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRKAVSDMLTAC
KQASFHPDVSEEVRTRALRYGTECTLGYLDLLEHVLVILQKPSPELKHQLAAFSKRVAGA
VTELIQAAEAMKGTEWVDPEDPTVIAETELLGAAASIEAAAKKLEQLKPRAKPKQADETL
DFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVGSIPANAADDGQWSQGLISAARM
VAAATSNLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMRRLQAA
GNAVKRASDNLVRAAQKAAFGKADDDDVVVKTKFVGGIAQIIAAQEEMLKKERELEEARK
KLAQIRQQQYKFLPTELREDEG
NT seq 7629 nt   +upstreamnt  +downstreamnt
atggtggccctgtccttaaagatttgtgtccgccactgcaatgtggtgaagaccatgcag
tttgaaccatctacggctgtgtatgatgcatgtcgagtcattcgagaacgggtacctgag
gcacaaactggccaagcttctgattatgggctgtttctttctgatgaagaccctaggaaa
gggatttggctggaagccggcagaacactggattattacatgttgcgaaatggggatatt
ttggaatataaaaagaaacagagacctcagaaaatccggatgctggatggatctgtgaaa
acagtgatggtggatgactccaagactgttggggaactcctggttactatttgcagcagg
ataggaataacgaactatgaagagtactctttaatccaagaaacgattgaagaaaagaag
gaggaagggacgggtacgctaaagaaagaccggacactgttgcgagatgagaggaaaatg
gagaagttgaaggccaagctccacacggatgacgacttaaattggctggatcacagccga
acattcagagaacaaggagtagatgaacatgaaacattgctgcttagacggaagttcttc
tactctgatcagaatgtggactcgagagaccccgtgcagctgaacttgctttatgttcag
gctcgggatgacatcctgaatggctcccaccccgtctccttcgagaaagcttgtgagttt
ggaggatttcaagcccagatacaatttggacctcacgtggaacataaacacaaacctgga
ttcttagatctaaaggaattcctgcccaaagaatacatcaagcagagaggagctgaaaag
agaatatttcaggagcataagaactgtggagagatgagcgaaatagaagccaaggtcaag
tatgtcaaactcgccagatccctccggacatatggtgtgtcctttttcctggtgaaggaa
aagatgaaaggcaagaacaagctggtgcctcgcctgttgggcatcaccaaggattcagtg
atgcgtgtggatgagaaaaccaaggaggtgctgcaggagtggccgctcaccacggttaag
cgctgggcggcctcacccaagagcttcaccctggattttggggagtatcaggaaagctac
tattcagtacaaaccactgaaggagagcaaatatcccagctgattgcaggctacattgac
atcatcctcaaaaagaaacaaagtaaagatagatttggattagagggggatgaggagtcg
actatgctggaagagtcggtttccccgaaaaagtccaccatcttgcagcagcagttcaat
cggactgggaaggtggagcatggctcagtggcgctgcccgccgtgatgcgctcaggctcc
agcggacccgagaccttcaacgtgggcagcatgccttcaccgcagcagcaggtcacggtg
gggcagatgcaccgaggacatatggccccactgacctcagcccaacaggccctcatgggg
accatcaacacaagcatgcacgctgtccagcaggcccaggacgacctcagcgagctggat
tcattgccacctctcggccaggatatggcgtcacgggtgtgggttcagaataaagttgat
gaatccaaacacgaaatccactctcaggttgatgcgatcacagctggaacagcttcagta
gttaacctcactgctggtgaccctgcagacactgactacacagcagtgggatgtgcaatc
accaccatttcctccaacctgacggagatgtccaagggtgtgaagctgttggccgctctg
atggacgacgaggtgggcagtggggaggacttgctccgagctgcgaggacccttgcaggg
gcagtatcagacttgctgaaagccgtgcagcctacttctggagagcctcgacagacagtt
ttgactgctgctggaagcattggacaagccagtggggatcttctgagacagatcggagag
aatgagaccgatgagcgattccaggatgttttaatgagtttggccaaagctgttgccaat
gctgctgccatgttggtattaaaggcgaagaatgttgcccaagtagctgaagacacagtc
ctacagaatagggtgattgctgctgctacccagtgtgcgctctctacatcccaacttgta
gcatgtgccaaggtggtaagccccaccatcagctcccctgtgtgccaggagcagctgatc
gaagcagggaagctggtggaccgctcagtggagaactgtgtccgcgcctgccaggcagcc
actgatgacagcgagctcctgaagcaggtcagcgcagcagccagtgtggtcagccaggcc
ctgcacgacctcctgcagcatgtacgacagtttgccagccgaggcgagcccatcggccgc
tacgaccaggccaccgacaccatcatgtgtgtcaccgagagcatcttcagctcaatgggc
gatgctggtgaaatggtacgccaggcccgggtcctggcacaggctacctcagacctcgtc
aatgccatgagatcagatgcagaagctgaaatcgacatggaaaattcaaagaagctcctg
gcagcagcaaaactcctggctgactctactgctcgcatggtggaagctgcaaagggggct
gcagccaatccagagaatgaggaccagcagcagagactgagggaagctgcagaaggtctt
cgagtggcaaccaatgccgctgcccagaatgccatcaagaaaaaaattgtcaaccgcttg
gaggtggcagctaagcaggctgcagccgcggccacgcagaccattgctgcctcccaaaac
gcagcagtgtccaacaagaaccctgccgcccagcagcagctggtgcagagttgcaaggcg
gtggctgatcacatcccccagctggtccagggagtgagagggagccaagcccaagcagaa
gaccttagtgcccagctggctctcatcatctccagccagaacttcctccagcctggaagc
aagatggtgtcctctgctaaagcagcagtgcccactgtgagtgaccaggctgcagccatg
cagctgagccagtgtgccaagaaccttgccaccagcttggcggagctgcgtactgcctcg
cagaaggcccacgaagcctgtggtcctatggaaattgattctgccctgagcaccgtgcag
acactcaagaatgaactgcaggatgccaagatggctgctgtggagagtcagctgaaacca
cttccgggggaaacgctggaaaaatgcgctcaagacctaggaagtacatccaaggcagtg
ggctcctccatggcacagctcctgacctgtgctgcccaaggcaatgagcactacacagga
gtggccgcaagagagacagcccaagctctgaaaacactggcccaggctgcgcgtggagtg
gccgcatccacaaatgatcctgcagctgcccatgccatgttagattctgctcgagatgtg
atggaaggctccgccatgctcatccaagaagccaagcaagccctgattgcacctggggat
gctgagagtcagcagagactagcccaggtggccaaagccgtctcacactccttgaataac
tgcgtgaattgtctccctggacagaaggatgtggacgtggccttgaagagcattggcgag
tccagcaagaagctgcttgtggactcgttacctcccagcacgaaacctttccaggaagcc
cagagtgaactaaaccaagcagcggctgatctgaaccagtctgctggggaagtggtccat
gccacccggggccagagcggagagctggccgcagcctctggaaagttcagtgacgatttt
gatgaattccttgatgctggcattgagatggcaggccaagctcagacgaaagaagaccag
atccaagtgataggaaacctcaagaatatctctatggcatccagcaagctgttgttagct
gccaagtctctatctgtagatccaggagcccccaatgcaaaaaatctcctggcagctgct
gcaagagctgtgacagagagtatcaatcagctcattactctgtgcacccagcaagctcca
ggccagaaagaatgtgataatgccctgcgggagctggagactgtcaaggggatgttggac
aatcctaatgaacctgtcagtgacctctcttactttgattgcattgagagtgtgatggaa
aactccaaggttctgggcgagtcgatggcagggatttcgcagaacgccaagactggggac
ctccctgcctttggggagtgtgtggggattgcgtccaaagccctctgtgggctgacagag
gctgcagcccaggctgcatacctggtgggcatctccgatccaaatagccaggcaggccac
cagggcctcgtggaccccatccagttcgccagggctaaccaggctatccagatggcatgc
cagaacctggtggaccccggcagcagcccgtcacaggttctgtcagcggccaccattgtc
gccaagcacacctcggccctgtgcaacgcctgccgcattgcctcgtccaagaccgccaac
ccagtggccaagagacactttgtccagtcagccaaggaagttgccaatagcactgccaac
ctagtgaagaccatcaaggccctggatggggatttctctgaagacaatcgcaataagtgt
cgcattgccaccgcacccttgatcgaagctgtggagaacctgacagcattcgcatccaac
cctgagtttgtcagcattcctgcccagattagctctgagggttctcaggcacaggaaccg
atcctggtctcagctaagaccatgctggagagttcatcatacctcattcgcactgcacgc
tcactggccatcaaccccaaagatccgcccacctggtctgtgctagctggacactcccac
actgtgtctgactctatcaagagtctcatcacctctatcagggacaaggcccctgggcag
agagagtgtgactactccatcgatggcatcaaccggtgcatccgggacattgagcaggcc
tctctggcagctgtcagccagagtttggccacgagggatgacatctctgtggaggccctg
caagagcagctaacttcagtggtccaagaaatcgggcaccttatcgatcccatcgccaca
gcggctcggggagaagcagctcagctgggacataaggtgacacagctggcgagctacttt
gagcccctgatcttagcagccgttggagtcgcctccaagatcctggatcatcagcagcag
atgacagtgctggaccagaccaagacgttggcagaatctgccctgcagatgttgtacgca
gccaaagaaggtggtggaaaccccaaggctcagcacacccacgatgccatcacagaggct
gcccagctcatgaaggaggctgtagatgacatcatggtgacactgaatgaagccgccagt
gaagtggggctggtgggaggcatggtcgacgccattgcagaggccatgagcaagctggat
gaaggcactcctccagaaccaaagggaacatttgtcgactatcagacgactgtggttaaa
tactccaaagccattgcggtgacagctcaggaaatgatgactaagtcggttactaacccg
gaggagttgggaggactggcttcacaaatgaccagtgactatgggcacctggccctccag
ggccagatggcggcagccacggcggaaccagaggagatcggcttccagattcgcactcgt
gtgcaagacctgggccacggctgtatcttcctggtgcagaaggcgggggcgctccagata
tgccccacagacagctacaccaaaagggagctcatcgagtgtgcccgcgcagtcacagag
aaggtgtccttggtgctatcagctctccaggctgggaacaaggggactcaggcatgtatc
acagccgccactgctgtgtctgggattattgccgacctggacaccaccatcatgtttgca
accgcggggaccctgaatgcagagaataacgagacctttgcagaccacagggagaacatc
ctgaagacagccaaagccttggtggaagatacgaagctgctggtgtcaggggctgcgtcc
acaccagacaagctggcccaggcggcccagtcatcagcagccaccatcacccagctcgct
gaggtggtcaagctgggggctgccagcctgggctctgatgaccccgagacacaggtggta
ttgatcaatgccatcaaagatgtagccaaggccctttcggatctgattggcgctaccaag
ggagctgccagcaagcctgctgatgacccctctatgtaccagctcaagggggcggccaag
gtgatggtgaccaatgtcacctccctcctcaagaccgtaaaggcagtggaggacgaggcc
acccgaggtacacgggcacttgaggccacaatcgagtacatgaaacaggagctcacggtg
ttccagtccaaagaagtacctgaaaagacctcctcacctgaagaatccataaggatgaca
aaaggcatcaccatggcgacagccaaagccgtggccgctgggaactcatgcaggcaggag
gatgtgattgccaccgccaacctgagccggaaagccgtgtcagatatgttgacagcttgt
aagcaagcctctttccaccctgatgtcagcgaggaggtgcgcaccagagctttgcggtac
gggacggagtgcacccttggctacctagaccttctcgagcacgtcttggtgatccttcag
aagccaagcccagaactcaagcaccaactggctgctttctccaagcgcgttgctggcgcc
gtgactgagctgatccaggccgcagaagccatgaaaggaacagagtgggtggatccagaa
gacccaaccgtcattgcagaaacagaattactgggggccgcagcatccattgaggctgct
gctaagaagttagagcaactgaagccaagagcaaaaccaaaacaagcagatgagaccctg
gattttgaagaacagattttggaagctgctaaatccattgctgctgccacaagtgccctg
gtcaaatcggcctcggcagcccagagggagctggtggcccaaggaaaggtgggttccatc
cctgccaatgctgcggatgacggacagtggtcccagggactgatttctgccgcccggatg
gtggcagctgcaaccagcaatctctgcgaggcggccaatgcctcagtgcagggacatgcc
agtgaggagaagctcatctcatctgccaagcaggtcgctgcctccacggctcagctgctc
gtggcctgcaaggtgaaggccgaccaggattcagaggccatgaggcggctacaggcagca
ggaaatgctgtgaaaagagcctcagataatctcgttcgtgcagcccagaaggcagcattt
ggcaaagccgatgatgacgatgttgtagtgaaaacaaagtttgtagggggcattgctcag
atcattgctgcccaggaggaaatgttgaaaaaagaacgagaactggaagaagcaaggaaa
aaactggcccagatccgccagcagcagtataaattcctacccactgagctgagggaggat
gaaggctaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (27)   
   UniProt (2)   
   RefSeq(pep) (25)   
DNA sequence (25)   
   RefSeq(nuc) (25)   
Protein domain (10)   
   Pfam (10)   
All databases (87)   

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