KEGG   Canis lupus familiaris (dog): 478981
Entry
478981            CDS       T01007                                 
Symbol
NDUFS2
Name
(RefSeq) NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial isoform X1
  KO
K03935  NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa00190  Oxidative phosphorylation
cfa01100  Metabolic pathways
cfa04714  Thermogenesis
cfa04723  Retrograde endocannabinoid signaling
cfa04932  Non-alcoholic fatty liver disease
cfa05010  Alzheimer disease
cfa05012  Parkinson disease
cfa05014  Amyotrophic lateral sclerosis
cfa05016  Huntington disease
cfa05020  Prion disease
cfa05022  Pathways of neurodegeneration - multiple diseases
cfa05208  Chemical carcinogenesis - reactive oxygen species
cfa05415  Diabetic cardiomyopathy
Module
cfa_M00143  NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    478981 (NDUFS2)
 09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    478981 (NDUFS2)
  09159 Environmental adaptation
   04714 Thermogenesis
    478981 (NDUFS2)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    478981 (NDUFS2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    478981 (NDUFS2)
   05012 Parkinson disease
    478981 (NDUFS2)
   05014 Amyotrophic lateral sclerosis
    478981 (NDUFS2)
   05016 Huntington disease
    478981 (NDUFS2)
   05020 Prion disease
    478981 (NDUFS2)
   05022 Pathways of neurodegeneration - multiple diseases
    478981 (NDUFS2)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    478981 (NDUFS2)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    478981 (NDUFS2)
Enzymes [BR:cfa01000]
 7. Translocases
  7.1  Catalysing the translocation of protons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.2  NADH:ubiquinone reductase (H+-translocating)
     478981 (NDUFS2)
SSDB
Motif
Pfam: Complex1_49kDa NiFeSe_Hases
Other DBs
NCBI-GeneID: 478981
NCBI-ProteinID: XP_536138
Ensembl: ENSCAFG00000012850
VGNC: 43707
UniProt: A0A8C0RNV5 A0A8I3Q1H1
Position
38:complement(21346459..21356011)
AA seq 463 aa
MAALRALRSLRGAAAQALRSGAGGRLPLQPSRGARQWQPDVEWAEQFGGAVMYPTKETAH
WKPPPWNDVDPPKDTMVTNLTLNFGPQHPAAHGVLRLVMELSGEMVRKCDPHIGLLHRGT
EKLIEYKTYLQALPYFDRLDYVSMMCNEQAYSLAVEKLLNIQPPPRAQWIRVLFGEITRL
LNHIMAVTTHALDIGAMTPFFWMFEEREKMFEFYERVSGARMHAAYVRPGGVHQDLPLGL
MDDIYEFSKNFSLRVDELEEMLTNNRIWKNRTVDIGVVTAEDALNYGFSGVMLRGSGIQW
DLRKTQPYDVYDQVDFDVPIGSRGDCYDRYLCRVEEMRQSLRIIEQCLNKMPPGEIKVDD
AKVSPPKRAEMKTSMESLIHHFKLYTEGYQVPPGATYTAIEAPKGEFGVYLVSDGSSRPY
RCKIKAPGFAHLAGLDKMSKGHMLADVVAIIGTQDIVFGEVDR
NT seq 1392 nt   +upstreamnt  +downstreamnt
atggcggcgctgagggctttgcgcagcctccggggcgccgcggcccaggcgctgcggtcg
ggggccggcggccggctgccgcttcagcccagcagaggtgctcggcagtggcagccagat
gtggaatgggcagagcagtttgggggagctgtcatgtaccccaccaaagaaacagcccac
tggaagcctccaccttggaacgacgtggaccctccaaaggacacaatggtgacaaacctg
accctgaactttgggccccagcacccagcggctcatggagtcctgcggctagtgatggag
ttgagcggggagatggtgcggaagtgtgacccccacatcggcctactacaccgaggcact
gagaagctcattgaatacaagacctatctgcaggcccttccatactttgaccgtctagac
tacgtgtccatgatgtgtaacgaacaggcctattcgctggccgtggagaagttgctcaat
atccagcctccgccacgggcacagtggatccgagtgctatttggagaaatcacacggctc
ttgaaccacattatggctgtgactacacatgccctggacattggagccatgacccctttc
ttctggatgtttgaagagagggagaagatgtttgaattctacgagcgcgtgtcaggggcc
cgcatgcatgctgcttatgtccggccaggaggtgtgcaccaggacctgcccctcgggctt
atggacgacatctatgagttttctaagaacttctctctccgggttgatgagctggaagag
atgctgaccaacaataggatttggaagaatcggacagttgacattggggttgtgacggcc
gaagacgcgctgaactatggatttagtggcgtgatgctccggggctcgggcatccagtgg
gacctgcggaagactcagccctatgacgtttatgaccaggtggacttcgatgttcctatt
ggctctcgaggggactgctatgacaggtacctgtgtcgggtggaggagatgcgccagtcc
cttcgaatcatcgagcaatgtctgaacaagatgcctcccggggagatcaaggttgatgat
gccaaagtgtctccgccgaagcgagcagagatgaagacttccatggagtcattgatccac
cacttcaagttgtacacggagggctaccaggtccctccgggggccacgtacactgccatc
gaggctcctaagggagagtttggggtgtacctcgtgtccgatggcagcagccgcccttac
cgatgcaagatcaaggctcctggttttgcccacctggctggtttggacaagatgtccaag
ggacacatgctggcggacgttgttgccatcataggtacccaagatatcgtgtttggagaa
gtggatcggtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (14)   
   KEGG PATHWAY (13)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (37)   
   KEGG ORTHOLOGY (1)   
   RefGene (31)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (7)   
   UniProt (2)   
   RefSeq(pep) (5)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (2)   
   Pfam (2)   
All databases (75)   

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