KEGG   Canis lupus familiaris (dog): 479074
Entry
479074            CDS       T01007                                 
Symbol
HTT
Name
(RefSeq) huntingtin isoform X2
  KO
K04533  huntingtin
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa05016  Huntington disease
cfa05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    479074 (HTT)
   05022 Pathways of neurodegeneration - multiple diseases
    479074 (HTT)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:cfa03019]
    479074 (HTT)
   04131 Membrane trafficking [BR:cfa04131]
    479074 (HTT)
   03029 Mitochondrial biogenesis [BR:cfa03029]
    479074 (HTT)
Messenger RNA biogenesis [BR:cfa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     479074 (HTT)
Membrane trafficking [BR:cfa04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    479074 (HTT)
Mitochondrial biogenesis [BR:cfa03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    479074 (HTT)
SSDB
Motif
Pfam: Htt_C-HEAT Htt_N-HEAT Htt_bridge Htt_N-HEAT_1 HEAT HEAT_2 DNA_pack_N
Other DBs
NCBI-GeneID: 479074
NCBI-ProteinID: XP_013968016
Ensembl: ENSCAFG00000014682
VGNC: 41839
UniProt: A0A8C0Q3X4
Position
3:complement(63660661..63805148)
AA seq 3093 aa
MATLEKLMKAFESLKSFQQQQQQQQQQPPPPPPPQPPQPLPQAQPPLPQPPPPPPPPPPP
GPAVAEEPLHRPKKELSATKKDRVNHCLTICENIVAQSLRNSPEFQKLLGIAMELFLLCS
DDAESDVRMVADECLNRVIKALMDSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHL
VRPQKCRPYLVNLLPCLTRISKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLLKAFI
ANLKSSSPTIRRTAAGSAVSICQHSRRTQYFYSWLLNVLLGLLVPVEGEHSTLLILGVLL
TLRYLVPLLQQQVKDTSLKGSFGVTRKELEVSPSTEQLIQVYELTLHYTQHQDHNAVTGA
LELLQQLFRTPPPELLQALSTPGGGLLNATQQQPGCRSRSSSIVELLAGGGSSCSPVLSR
KQKGKVLFGEAAALDDDSESRSEGSSPAFTASVKGEIGGELAASSGVSTPGSASSATDSV
GHDIITEQPRSQHTLQPDSVDLTSCDLASAATDGDEEDILSHSSSQISAVPSDPAMDLND
GTQASSPVSDSSQTTTEGPDSAVTPSDSSEIVLDGADSQYSGMQIGQPQDEDEETAGILP
DEDADAFRTSSVALQQAHLLKSMGHSRQPSDSSIDKFVSRDEATETGDQENKPCRIKGDI
GQSTDDDSVPLVHCVRLLCASFLLTGEKNVLVPDRDVRVSVKALALSCVGAAVALHPESF
FSKLYKVPLDTMEYPEEQYVSDILNYIDHGDPQVRGATAVLCGTLISSILSRSRFQVGDW
MGTVRTLTGSTFSLADCVPLLQKTLKDESSVTCKLACTAVRHCVMSLCSSSYSELGLQLI
TNVLTLKDSSYWLVRTELLETLAEIDFRLVSFLETKAENLHRGTHHYTGLLKLQERVLHD
VVIYLLGDEDPRVRHVAAAALMRLVPKLFYKCDQGQADPVVAVARDQSSVYLKLLMHEAQ
PPSHFSVSTITRIYRGYNLLPSMTDVTVENNLSRVIAAVSRELVTSTTRALTFGCCEALC
LLSTAFPVCIWSLGWHCGVPPLSTSDESRKSCTVGMATMILTLLSSAWFPLDLSAHQDAL
VLAGNLLAASAPKSLRSSWTSEEEANPATSKQEEVWPALGDRTLVPMVEQLFSHLLKVIN
ICAHVLDDVAPGPAIKAALPSLTNPPSLSPIRRKGKEKEPGEPASVPLSPKKGSEASPAS
RQSDAPGPVTANKSSSLGSFCHLPSYLKLHDVLKATHANYKCVEEILGYLKSCFSREPVM
ATVCVQQLLKTLFGTNLASQFDGLSSNPSKSQGRAQRLGSSSVRPGLYHYCFMAPYTHFT
QALADASLRTMVQTEQDHGTSGWFDVLQKVSTQLKTNLTSATKNRADKNAIHNHIRLFEP
LVIKALKQYTTTTSVQLQRQVLDLLAQLVQLRVNYCLLDSDQVFIGFVLKQFEYIEVGQF
RESEAIIPNIFFFLVLLSYERYHSKQIIGIPKIIQLCDGIMASGRKAVTHAIPALQPIVH
DLFVLRGTNKADAGKELETQKEVVVSMLLRLIQYHQVLEMFILVLQQCHKENEDKWKRLS
RQIADVILPMLAKQQMHIDSHEALGVLNTLFEILAPSSLRPVDMLLRSMFVTPDTMASVS
TVQLWISGILAILRVLISQSTEDIVLSRIQELSFSPYLISCPIINRLRDGDSTSIPEEHH
EGKQMKTLPEETFSRFLLQLVGILLEDIVTKQLKVEMSEQQHTFYCQELGTLLMCLIHIF
KSGMFRRITAAASRLFTVDSTDGSFYGLERLNARVRAMVPTHPALVLLWCQILLLVSHTD
YRWWAEVQQTPRRRSLSSTKSLNPQMCGEEEDPDAACKLGMCNREIVRRGALILFCDYVC
QNLHDSEHLTWLIVNHIQDLINLSHEPPVQDFISAVHRNSAASGLFIQAIQSRCENLSTP
TTLKKTLQCLEGIHFSQSGAVLTLYVDKLLCTPFRVLARMVDTLACRRVEMLLAANLQSG
MAQLPVEEVSRVQEYLQRSGLAQRHQRLYSLLDRLRLATAPGSRGPSPPVTSHPLDGDGP
LALEIVIPDKDWYLRLVKSQCWTRSDSALLEGAELVNRIPPSDMSTFMMNSEFNLSLLAP
CLGLGMREISGGQRSPLFEAARLVTLDRVTSLVQQLPAVHHVFQPFLPMEPTAYWSKLND
LFGDAVLYRSLTTLARALAQYLLVFSKLPSHLHLPPEKERDTVKFVVMTLEALAWHLIHE
QIPLSLDLQAGLDCCCLALQLPSLWSVLSSPEMVTHACSLIHCVRFILEAVVVQPGDQLL
SPERRVNMPKAARVDEVDPNTQNLAYITTACQMVAEMVESLPSVLALGHKRNSNTPAFLT
SVLRNIVISLARLPLVNSYTRVPPLVWKLGWSPEPGGDFGTAFPEIPVEFLQEKEVFKEF
IYRINALGWTSRTQFEETWATLLGVLVTQPLVMEQEESPPEEDTERTQINVLAVQAITSL
VLSAMTVPVAGNPAVSCLEQQPRNKPLKALDTRFGRKLSIIRGIVEQEIQAMVSKRENIA
THHLYQAWDPVPSLSPATTGALISHDKLLLQINPERELGNMSYKLGQVSIHSVWLGNSIT
PLREEEWEEEEEEEADVPAPASPPTSPVNSRKHRAGVDIHSCSQFLLELYSRWILPSGSA
RRTPIILISEVVRSLLVVSDLFTERTQFEMMYLTLTELRRVHPAEDEILIQYLVPATCKA
AAVLGMDKAVAEPVSRLLETTLRSSHLPSKVGALHGALYVLECDLLDETAKQLVPVISDY
LLSNLKGAAHCVNIHSQQHVLVMCATAFYLIENYPLDVGPEFSASIIQMCGVMLSGSEES
TPSIIYHCILRGLERLLLSEQLCRLDAESLVKLSVDRVNVHSPHRAMAALGLMLTCMYTG
KEKISPGRTSDPSPTAPDSESVIVAMERVSVLFDRVRKGFPCEARVVARILPQFLDDFFP
PQDVMNKVIGEFLSNQQPYPQFMATVVYKVFQTLHSTGQSSMVRDWVMLSLSNFTQRTPV
AMAVWSLSCFFVSASTSPWVSAVLPHVISRMGKLEQVDVNLFCLVATDFYRHQIEEELDR
RAFQSVFEVVAAPGNPYHRLLTCLRNVHKVTMC
NT seq 9282 nt   +upstreamnt  +downstreamnt
atggcgaccctggaaaagctgatgaaggccttcgagtccctcaagtccttccagcagcag
cagcaacagcagcagcagcagcctccgccgccgccacctcctcagcctcctcagccgctg
ccgcaggcgcagccgccgctaccgcagccgcccccgccgcccccgcccccgccgcccccg
ggcccggcggtggccgaagagccgctgcaccgaccaaagaaagaactctcagctaccaag
aaggaccgcgtcaatcattgtctgacaatatgtgaaaacatagtggcacagtcactcaga
aattctccagaatttcagaaacttctgggcatcgctatggaactttttctgctgtgcagt
gatgatgcagagtcggatgtccggatggtggctgacgagtgcctcaacagagtcataaaa
gccctgatggactctaatcttccgaggttacagttagaactctataaggaaatcaaaaag
aacggtgctccccggagcctgcgcgctgccctgtggaggtttgctgagctggctcacctg
gttcggcctcagaaatgcaggccttacttggtaaaccttttgccttgcctgactcgaata
agcaagagacctgaggaatctgttcaggagaccttggctgcagctgtacccaaaattatg
gcttcttttggcaattttgcaaatgacaatgaaattaaggttctattaaaggctttcata
gcgaatctgaagtcaagctccccgaccattcgacggacagcagctggctcagcagtgagc
atctgccagcactcaagaaggacacagtatttttacagctggctactaaatgtgctttta
ggtttgctggtccctgttgagggtgaacactctaccctcctgattcttggagtgctgctc
acactgaggtatctggtgcctttactgcagcagcaggttaaggacacgagcctgaaaggc
agctttggagtgacacggaaagaactggaagtctctccctcaacagagcaactcatccag
gtttatgaactgaccttgcattatactcagcaccaagaccacaacgctgtgactggagcg
ctggagctcctgcagcagctgttccgcacgcccccgcccgagctcctgcaggctctgagc
acacccggtggcgggctgctcaatgccacgcagcagcagcctgggtgccggagccgcagc
agcagcatcgtggagctcctagctggagggggttcttcatgcagccctgtcctttcaaga
aaacaaaaagggaaagtgctcttcggagaagcggcagccttggatgatgactccgagtcc
aggtcggagggcagcagccccgccttcacagcctcggtcaagggtgagattggtggtgag
ctggctgcctcttccggggtctctactcctggctctgccagttcagccaccgactccgtg
gggcatgacatcatcaccgagcagccccggtcacagcacacactgcagccagactcagtg
gatctgaccagctgtgacctggcgagtgctgccaccgatggggatgaggaggacatcttg
agccacagctccagccagatcagtgctgtcccgtcggacccagccatggacctgaacgat
ggcacccaggcctcctccccggtcagcgacagctcccagaccaccactgaagggccggat
tcagctgtgaccccctcagacagttctgaaattgtgttagatggtgctgacagccagtat
tcggggatgcagattggacagccacaggacgaggatgaggaaaccgcaggcattcttcca
gatgaagatgcagatgctttcagaacctcttcagttgcccttcagcaagcacatttattg
aaaagcatgggccacagcaggcagccctctgacagcagtatagacaagtttgtctccaga
gatgaagctaccgaaacaggagatcaagaaaacaagccttgccggatcaaaggtgacata
ggacagtctaccgatgatgattctgttcctcttgtccattgtgtccgcctcctgtgtgcg
tcatttttgctgactggggagaaaaatgttttggttccagacagggacgtgcgggtcagt
gtgaaggcactggcactcagctgtgttggagctgctgtggcccttcatcctgaatctttc
ttcagcaaactttataaagtacctcttgacaccatggaataccctgaggagcagtatgtg
tcagacatcctgaactacatcgaccatggagacccccaagtcagaggagccacagccgtt
ctctgcggaaccctcatctcctctatcctcagcagatcccgcttccaggtgggagattgg
atgggcaccgtcaggaccctgacaggaagtacattttctctggcggactgtgttcctttg
ctgcagaaaactttgaaggatgaatcttctgttacttgcaagttggcttgtacagctgtg
aggcactgtgtcatgagtctctgcagcagtagctatagtgaattgggattacagctgatc
accaacgtgctgaccctaaaggatagttcctactggttggtgaggacggagctcttggaa
actcttgcagagattgactttcggttggtgagctttttggagacaaaagcagaaaacctg
cacagagggactcatcattacacagggcttttaaaactacaagaacgagtgctccatgat
gttgtcatctatctgcttggggatgaggaccccagagtgcggcatgttgctgcagcggca
ttaatgaggcttgtcccaaagctgttttataagtgcgaccaagggcaagctgaccccgtg
gtggctgtggcgcgagatcaaagcagtgtttacctgaagctcctcatgcacgaggcgcag
cctccatctcacttctccgtcagcaccataaccagaatctacagaggctataacttacta
ccgagcatgacagacgtcactgtggaaaacaacctctccagagtcattgcggcagtttcc
cgtgaattggtcacgtcaaccacacgcgcgctcacatttggatgctgcgaagctctgtgt
ctcctttcaactgcctttcctgtctgcatttggagtttaggttggcattgtggggtgcct
ccactaagcacctcagatgagtctagaaagagctgtactgttggcatggccacgatgatc
ctcaccttgctctcgtctgcttggttcccactggatctctctgcccatcaggatgctttg
gttttagccggaaacttacttgcagccagtgcccccaaatctctgagaagttcatggacc
tctgaagaggaggccaacccagcaacctccaagcaggaagaggtctggccagctttgggt
gaccggaccctggtgcccatggtggagcagctcttctcccacttgctgaaggtgattaac
atctgtgctcacgtcttggacgatgtggctcccggaccagcaataaaggcagccttgccg
tctctgacaaaccctccttccctaagtcccatccgacggaagggaaaggagaaagaacct
ggagagccagcctctgtgcccttgagccccaagaaaggcagcgaagccagtccagcctct
cgacaatctgatgccccaggacctgttacagcaaataagtcctcgtcgttggggagtttc
tgtcaccttccttcatatctcaaattgcacgatgtcctgaaagctactcacgccaactat
aagtgtgttgaggagatactagggtatctgaaatcctgtttcagtcgagaaccagtgatg
gcaactgtttgtgttcaacagttgttgaagactctctttgggacaaacttggcctcccag
tttgatggcttatcttccaaccccagcaagtctcaaggccgagcacagcgtctgggctcg
tccagcgtgagaccaggcttgtatcattactgtttcatggctccatacacccacttcacc
caggccttagccgatgccagcttgaggaccatggtgcagacggagcaggaccacggcaca
tcagggtggtttgatgtgcttcagaaggtgtctacgcagttgaagaccaacctcacgagt
gccactaagaaccgtgcagataagaatgctattcataatcacatacgtttgttcgagcct
ctggttataaaagctttaaaacagtacacaaccacaacgtctgtgcagctgcagaggcag
gttttagacttgctggcacagctggttcagttacgggtcaattactgtcttctggactca
gatcaggtgtttattggatttgtgctgaagcagtttgagtacattgaagtaggccagttc
agggaatcagaggcaattattccaaacatctttttcttcctggtattactatcttatgaa
cgctatcattcaaaacagatcattggaattcctaaaatcattcagctctgtgatggcatc
atggccagtgggaggaaggctgtgacacatgccataccggccctgcagcccatagtccat
gatctctttgtactgagaggaaccaataaagccgatgcaggaaaagagcttgaaacccaa
aaagaggtggtggtgtcaatgttactgagactcatccagtaccatcaggtgctggagatg
ttcatcctggttctacagcagtgccacaaggagaatgaagataagtggaagcgactgtct
cggcagatagcagatgtcatcctcccgatgttagccaagcagcagatgcacattgattct
catgaagcccttggagtgttaaatactttatttgagatcctggctccttcttccctccgt
cctgtggacatgcttttacgaagtatgtttgtcactccagatacaatggcatctgtgagc
actgtccaactgtggatatcaggaatcctagccattttgagagttctaatttcccagtca
actgaagatattgttctttctcgtattcaggagctctccttctccccatatttaatttcc
tgtccaataattaataggttaagagatggggatagtacttcaataccagaagaacaccat
gaagggaaacaaatgaagactttgccagaggaaacattttcaaggtttttactacaacta
gttggcattcttttggaggatattgttacaaaacagctaaaagtagaaatgagtgaacag
caacatactttctattgtcaagaactaggcaccctgctcatgtgtctgatccacatcttc
aagtctggaatgttccggagaatcacagcagctgcctctagactcttcacggtagacagc
accgacggcagtttctatggcctagagaggctgaacgcccgggtgcgtgccatggtgccc
acacatccagccctcgtgctgctctggtgccagatcctgctgctcgtcagccacaccgac
taccgctggtgggcagaggtgcagcagacccccaggagacgcagtctgtccagtaccaag
tcactcaacccccagatgtgtggagaagaggaggatcccgatgcagcatgcaagcttggg
atgtgcaatagagaaatagtgcgaaggggagctctcattctcttctgcgattatgtctgt
cagaacctacacgattcagagcacctaacgtggctcatcgtgaatcatatccaggacctg
atcaatctgtcccatgagcctcccgtgcaggattttattagtgctgttcatcggaactct
gctgccagtggccttttcatccaggcaattcagtctcgttgtgaaaatctttccacccct
accactctgaagaagacgcttcagtgcttggaagggatccacttcagccagtcgggtgcc
gtgttaaccctatatgtggacaagcttttgtgcactccgttccgtgtgctggctcgcatg
gtcgacactctagcctgtcgccgggtggaaatgcttctggctgcaaatttacagagtggc
atggcccagctgccagtggaggaagtgagcagagtccaggagtacctgcagcgcagcggg
ctggcccagagacaccaaaggctctactccctgctggacaggctgcgtcttgccactgca
ccgggctcacgtggcccttcacctccagttacctcccacccgctggacggggatgggccc
ctggcactagagatagtgattccagataaagactggtacctacgtctagtcaaatcccag
tgctggactaggtcagattctgcactgctagaaggggcagaactggtgaatcggattcct
cccagtgacatgagtacattcatgatgaactcggaattcaacttaagtctgttggctcca
tgcctgggcctgggcatgcgcgaaatctccggaggccagaggagtcccctttttgaagca
gctcgcctggtgacactggaccgcgtgaccagcctggtccagcagctccctgctgtccat
catgtgttccagccattcctgcctatggagcccaccgcctactggagcaagttgaatgat
ctatttggggatgccgtgttgtatcggtccttgaccactctggcccgggccctagcccaa
tacctgcttgtgttctccaaactgcccagccatttgcacctacctcctgagaaggagagg
gacactgtgaagtttgtggtcatgacccttgaggccctggcatggcatttgatccatgag
cagatcccactgagtctggaccttcaggcaggcctcgactgctgttgcctggctctgcag
ctgcccagcctctggagtgtgctctcctccccagagatggtgacccatgcctgctctctc
attcactgtgtccgcttcatcctagaagccgtcgtggtgcagcctggggaccagctgctt
agcccagaaaggagggtgaacatgccaaaggccgccagagtggacgaagtagatccaaac
acacaaaatctagcatatatcaccacagcctgtcagatggtggcagaaatggtggagtct
ttgccatcagtgttggccttggggcacaagaggaacagcaacaccccagcgtttctcaca
tcagtgctgaggaacatcgtcatcagcctggctcgcttacccctcgtcaatagctacacg
cgtgtccccccgctggtttggaaactcggatggtcgcctgagccaggaggggacttcggc
acagccttccctgagatcccagtggagttcctccaggagaaggaagtctttaaagagttc
atctaccgcatcaatgcactaggatggaccagccgcacccagtttgaggaaacgtgggcc
accctccttggtgtcctggtgactcagccccttgtgatggagcaggaagagagcccaccg
gaagaagacacagagaggacccagatcaacgtcctggctgtgcaggccatcacctccctg
gtgctgagtgcaatgactgtgcctgtggctggcaacccagctgtgagctgcttggagcag
cagccccggaacaagcccctgaaagccctcgacaccaggtttgggaggaagttgagcatt
atccgaggaattgtagagcaggaaatccaagcaatggtttcaaagagagagaatatcgcc
acgcatcacttataccaagcgtgggaccctgtcccttctctgtctccagctactacaggt
gccctcatcagccacgacaagcttctgctgcagatcaaccccgagcgggagctgggaaac
atgagctataagcttggccaggtgtccattcactccgtgtggctggggaacagcatcaca
cccttgagagaggaggagtgggaggaggaggaagaagaggaggctgatgtccctgcacct
gcatcaccacccacatcacccgtcaactccaggaagcaccgggctggagtcgacattcac
tcctgttcccagtttttgcttgaattgtacagtcgctggatcctgccatcaggttcggcc
agaaggacacccatcatcctgatcagtgaagtggttcgatccctcctcgtggtctcagac
ttattcactgagcgcacccagtttgagatgatgtatctgacgctgacggaactgcggagg
gtgcaccctgcagaagacgagattctcattcagtacctggtgcccgccacctgcaaggca
gctgccgtccttggaatggacaaggccgtggcagagccagtcagccggctgctagagacc
acgctgaggagcagccaccttcccagcaaggtcggagccctgcacggtgctctctacgtg
ctggagtgtgacctcctggatgagacggcaaagcagctcgtcccagtcatcagcgactac
ctcttgtccaacctcaaaggggcagcacactgtgtgaacattcatagccagcagcacgtg
ctggtgatgtgcgccactgccttttacctgatcgagaactaccccctggatgtaggcccg
gaattctctgcatcaataatacagatgtgtggggtgatgctgtctggaagtgaggagtcc
accccgtctattatctaccactgtatcctgcggggtctggagcgcctcctgctctctgaa
caactctgccggctggatgcagagtccctggtcaagcttagtgtggacagagtgaacgtg
cacagcccacatcgggccatggctgccctgggcctgatgcttacctgcatgtacacaggg
aaggagaaaatcagcccgggcagaacctcagaccccagccccaccgccccagacagcgag
tcagtgattgtggctatggagcgtgtgtctgtactttttgacagggtcaggaaagggttc
ccctgtgaagccagagtggtggcacggatccttcctcagtttttagatgacttcttccca
ccccaggacgtcatgaacaaagtcattggagaatttctgtccaaccagcagccgtaccca
cagttcatggccaccgttgtatataaggttttccagactctgcacagcaccgggcagtcg
tccatggtccgagactgggtcatgctgtctctgtccaacttcacacaaaggacgccagtg
gccatggccgtgtggagcctctcctgcttctttgtcagtgcttccaccagcccgtgggtc
tcggcagtccttccccacgttatcagcaggatgggcaagctggaacaagtggacgttaac
ctcttctgcctggtggccacggacttttacagacaccagatagaggaggagctggaccgc
cgggccttccagtctgtgttcgaggtggtcgcggcaccaggaaacccgtatcatcgattg
ctgacttgtttgcggaatgtccacaaagtcaccatgtgctga

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (2)   
   KEGG PATHWAY (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (38)   
   KEGG ORTHOLOGY (1)   
   RefGene (32)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (11)   
   UniProt (1)   
   RefSeq(pep) (10)   
DNA sequence (10)   
   RefSeq(nuc) (10)   
Protein domain (7)   
   Pfam (7)   
All databases (73)   

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