KEGG   Canis lupus familiaris (dog): 479406
Entry
479406            CDS       T01007                                 
Symbol
HSPA8
Name
(RefSeq) heat shock cognate 71 kDa protein
  KO
K03283  heat shock 70kDa protein 1/6/8
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa03040  Spliceosome
cfa04010  MAPK signaling pathway
cfa04141  Protein processing in endoplasmic reticulum
cfa04144  Endocytosis
cfa04213  Longevity regulating pathway - multiple species
cfa04612  Antigen processing and presentation
cfa04915  Estrogen signaling pathway
cfa05020  Prion disease
cfa05134  Legionellosis
cfa05145  Toxoplasmosis
cfa05162  Measles
cfa05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03040 Spliceosome
    479406 (HSPA8)
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    479406 (HSPA8)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    479406 (HSPA8)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    479406 (HSPA8)
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    479406 (HSPA8)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    479406 (HSPA8)
  09149 Aging
   04213 Longevity regulating pathway - multiple species
    479406 (HSPA8)
 09160 Human Diseases
  09172 Infectious disease: viral
   05162 Measles
    479406 (HSPA8)
  09171 Infectious disease: bacterial
   05134 Legionellosis
    479406 (HSPA8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    479406 (HSPA8)
  09164 Neurodegenerative disease
   05020 Prion disease
    479406 (HSPA8)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    479406 (HSPA8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:cfa01009]
    479406 (HSPA8)
  09182 Protein families: genetic information processing
   03041 Spliceosome [BR:cfa03041]
    479406 (HSPA8)
   03009 Ribosome biogenesis [BR:cfa03009]
    479406 (HSPA8)
   03110 Chaperones and folding catalysts [BR:cfa03110]
    479406 (HSPA8)
   04131 Membrane trafficking [BR:cfa04131]
    479406 (HSPA8)
   03051 Proteasome [BR:cfa03051]
    479406 (HSPA8)
   03029 Mitochondrial biogenesis [BR:cfa03029]
    479406 (HSPA8)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:cfa04147]
    479406 (HSPA8)
Protein phosphatases and associated proteins [BR:cfa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-5
    PP5-interacting proteins
     479406 (HSPA8)
Spliceosome [BR:cfa03041]
 Complex B
  Other components
   Prp19 complex
    479406 (HSPA8)
 Complex C
   Prp19-CDC5 complex
    479406 (HSPA8)
Ribosome biogenesis [BR:cfa03009]
 Eukaryotic type
  Pre-60S particles
   Export and cytoplasmic maturation factors
    479406 (HSPA8)
Chaperones and folding catalysts [BR:cfa03110]
 Heat shock proteins
  HSP70 / DNAK
   479406 (HSPA8)
Membrane trafficking [BR:cfa04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Other core components
    479406 (HSPA8)
 Autophagy
  Chaperone mediated autophagy (CMA)
   Chaperones
    479406 (HSPA8)
Proteasome [BR:cfa03051]
 Eukaryotic proteasome
  Assembling factors
   Other assembling factors
    479406 (HSPA8)
Mitochondrial biogenesis [BR:cfa03029]
 Mitochondrial protein import machinery
  Endoplasmic reticulum membrane and cytosol
   Other ER-memrane and cytosol factors
    479406 (HSPA8)
Exosome [BR:cfa04147]
 Exosomal proteins
  Proteins found in most exosomes
   479406 (HSPA8)
SSDB
Motif
Pfam: HSP70 MreB_Mbl FGGY_C DDR Hydantoinase_A Radial_spoke_3
Other DBs
NCBI-GeneID: 479406
NCBI-ProteinID: XP_005619707
Ensembl: ENSCAFG00000011666
VGNC: 59028
UniProt: A0A8C0LZQ6 A0A8I3NK47
Position
5:11348073..11352702
AA seq 646 aa
MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA
MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS
SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA
IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH
FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA
RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN
KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI
PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDI
DANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKN
SLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELE
KVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD
NT seq 1941 nt   +upstreamnt  +downstreamnt
atgtctaagggacctgcagtcgggatcgatcttggcaccacctactcctgcgtgggtgtc
ttccagcacgggaaagtggaaataattgccaatgatcagggaaaccgaaccaccccaagt
tatgtcgccttcacggacaccgaacgattgatcggtgatgctgcgaagaatcaagttgcg
atgaaccccaccaacacggttttcgatgccaagcggctgattggacgtagatttgatgat
gctgtcgtccaatctgatatgaagcattggcctttcatggtggtgaatgatgctggcagg
cctaaagtccaagtagagtacaagggggagaccaaaagtttctatccagaggaggtgtcc
tctatggtcctgacgaagatgaaggaaattgcagaggcctaccttgggaagactgttacc
aatgcagttgtcacggtacctgcatacttcaatgactctcagcgtcaggctaccaaagat
gctggaactattgccggtcttaatgtacttcgaattatcaatgagccaactgctgctgct
attgcttatggcttagacaagaaggttggagctgaaaggaacgtgttgatctttgattta
ggaggtggcacttttgatgtgtccatccttactattgaagatgggatctttgaggtcaag
tccacagctggagacactcacttaggtggagaagactttgacaacagaatggtcaaccat
tttattgcagaattcaagcgcaaacacaagaaggacatcagcgaaaacaagagggctgtc
cgccgtctccgtactgcatgtgaacgggctaagcgtacactttcttccagcacccaggcc
agtattgagattgattctctgtatgaaggaatcgacttctatacctctattactcgtgcc
cggtttgaagaattaaatgctgacctcttccgtggcaccctggaccctgtagagaaagct
cttcgagatgccaagctggacaagtctcagatccatgacattgtcctggtgggtggttct
acccgtatccccaagattcagaaacttctgcaagatttcttcaatggaaaggaactgaat
aagagcatcaaccctgatgaggctgttgcttatggtgcagctgtccaggcagccattctt
tctggtgacaaatctgaaaatgttcaagatttgctgctattggatgtcaccccactttct
cttggtattgaaactgctggaggagtcatgactgtgctcatcaagcgcaatactaccatt
cctacaaaacagacacaaacctttactacctactctgacaaccagcctggtgtgcttatt
caggtctatgaaggtgagcgtgctatgaccaaggataacaacctacttggcaagtttgaa
ctcacaggcatacctcctgctcctcgtggcgttcctcagattgaagtcacttttgatatt
gatgcaaatggtatcctcaatgtgtctgctgtggataagagcacaggaaaagagaataag
attaccatcactaatgacaagggccgcttgagcaaggaggacattgagcgcatggtccag
gaagctgagaagtacaaagccgaagatgagaagcagagagacaaggtgtcttccaagaat
tcacttgagtcttatgctttcaacatgaaagcaactgttgaagatgaaaaacttcagggc
aaaatcaatgatgaagacaaacagaagattcttgacaagtgcaatgaaatcatcaactgg
ctcgataagaaccagactgcagagaaggaagaatttgaacatcagcagaaagagctggag
aaagtctgcaatcccatcattacgaagctataccagagtgcaggaggcatgccaggagga
atgcctggaggctttcctggtggtggagctcctccctctggtggtgcctcctctgggcct
accattgaagaggttgattaa

  All links  
Ontology (9)   
   KEGG BRITE (9)   
Pathway (12)   
   KEGG PATHWAY (12)   
Genome (1)   
   KEGG GENOME (1)   
Gene (103)   
   KEGG ORTHOLOGY (1)   
   RefGene (97)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (7)   
   UniProt (2)   
   RefSeq(pep) (5)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (6)   
   Pfam (6)   
All databases (143)   

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