KEGG   Canis lupus familiaris (dog): 480118
Entry
480118            CDS       T01007                                 
Symbol
CAPN2
Name
(RefSeq) calpain-2 catalytic subunit
  KO
K03853  calpain-2 [EC:3.4.22.53]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04141  Protein processing in endoplasmic reticulum
cfa04210  Apoptosis
cfa04217  Necroptosis
cfa04218  Cellular senescence
cfa04510  Focal adhesion
cfa05010  Alzheimer disease
cfa05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    480118 (CAPN2)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    480118 (CAPN2)
   04217 Necroptosis
    480118 (CAPN2)
   04218 Cellular senescence
    480118 (CAPN2)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    480118 (CAPN2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    480118 (CAPN2)
   05022 Pathways of neurodegeneration - multiple diseases
    480118 (CAPN2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:cfa01002]
    480118 (CAPN2)
Enzymes [BR:cfa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.53  calpain-2
     480118 (CAPN2)
Peptidases and inhibitors [BR:cfa01002]
 Cysteine peptidases
  Family C2: calpain family
   480118 (CAPN2)
SSDB
Motif
Pfam: Peptidase_C2 Calpain_III EF-hand_1 EF-hand_6 EF-hand_8 EF-hand_7
Other DBs
NCBI-GeneID: 480118
NCBI-ProteinID: XP_038425753
Ensembl: ENSCAFG00000016416
VGNC: 53334
Position
7:complement(39815620..39853714)
AA seq 700 aa
MAGIAAKLVRDREAAEGLGSHERAIKYLNQDYGALRDECLEAGALFQDPSFPAIPSSLGF
KELGPYSSKTQGIEWKRPTEICDDPQFIVGGATRTDICQGALGDCWLLAAIASLTLNEEV
LARVVPPNQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKNGELLFVHSAEGSEFWSAL
LEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELRKAPPDLFRIIQKALQKGSLLGC
SIDITSMADSEAITFQKLVKGHAYSVTGAEEVESGGSLQKLIRIRNPWGEVEWTGKWNDN
CPNWNTVDPEVRERLTRRHEDGEFWMSFSDFLRHYSRVEICNLTPDTLTSESYKKWKLTK
MDGSWRRGSTAGGCRNYPNTFWMNPQYVIKLEEEDEDQEDGERGCTFLVGLIQKHRRRQR
KMGEDMHTIGFGIYEVPEEMTGQTNIHLSRNFFLTHRARERSDTFINLREVLNRFKLPPG
EYILVPSTFEPNKDGDFCVRVFSEKKADYQVVDDEIEADLEEIDASEDDIDDGFRRLFAQ
LAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYVL
WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFD
NFVRCLVRLETLFRIFKQLDPEGSGTIELDLISWLCFSVL
NT seq 2103 nt   +upstreamnt  +downstreamnt
atggccggcatcgcggccaagctggtgagggaccgagaggcagccgaggggctgggctcg
cacgaacgggccatcaagtacctcaaccaggactacggggcgctgcgggacgagtgcctg
gaggccggggcgctcttccaggacccctccttcccggccatcccctcctccctgggcttc
aaggagctggggccctactccagcaagacccagggcatcgagtggaagcggcccacggag
atctgcgatgatccgcagttcattgttggaggcgctacccgcacggacatctgccaggga
gccctgggtgactgctggctgctggcagccattgcctccctgaccttgaacgaagaggtc
ctggctcgtgttgtgcccccgaaccagagcttccaggaaaactatgcagggatcttccac
ttccagttctggcagtacggcgagtgggtggaggtggtggtggacgacaggctgcccacc
aagaacggggagctgctcttcgtgcactctgcagagggcagcgagttctggagcgcgctg
ctggagaaggcctacgccaagatcaacggctgttacgaggcactctcggggggtgccacc
actgagggctttgaggactttaccggggggatcgcggagtggtacgagctgaggaaggcc
ccccctgacctgttcaggatcatccagaaggctctgcagaaaggctccctcctcggctgc
tccatagacatcaccagcatggcagactcagaggccatcacgttccagaagctggtgaag
gggcacgcgtactcagtcactggggccgaggaggtcgaaagtgggggcagcctgcagaag
ctgatccgcatccgcaacccttggggcgaagtggagtggaccgggaagtggaatgacaac
tgccccaactggaacacggtggacccagaggtgagggagaggctgaccagacggcacgag
gacggggaattctggatgtctttcagtgacttcctgaggcactactcccgagtggagatt
tgcaacctgacccccgacaccctcaccagcgagtcctataagaagtggaagctcaccaag
atggatgggagctggagacggggctccacggctggaggctgcaggaactacccgaatacc
ttctggatgaaccctcagtacgtgatcaagctggaagaggaggacgaggaccaggaggat
ggagaacgcggctgcacgttcctcgtgggcctcatccagaagcaccggcggcggcagcgc
aagatgggcgaggacatgcacaccatcggcttcggcatctacgaggtcccagaggagatg
accggacagaccaacatccacctcagcagaaacttcttcctgacgcacagagcaagagag
cgctctgacactttcatcaacctgcgcgaggtcctcaaccggttcaagctgcccccgggg
gagtacatcctggtgccctccaccttcgagcccaacaaggacggggacttctgtgtccgg
gtcttttcagagaagaaggccgactaccaggtcgtggacgacgagatcgaggccgacctt
gaggagatagacgccagcgaggacgacattgacgacggcttcagaaggctgtttgcccag
ctggcaggcgaggacgcagagatttctgcctttgagctgcagaccatcctgagaagagtg
ctggccaagcgccaggacatcaagtcagacggcttcagcatcgagacctgcaaaatcatg
gtggacatgctggactcagatggcagtgggaagctgggcctgaaagagttctatgttctc
tggacaaagatccagaagtaccagaaaatttaccgggagatcgatgtggaccggtctggc
accatgaactcctacgagatgcggaaagcacttgaggaagcaggcttcaagctgccctgt
cagctccaccaggtcatcgttgctcgctttgcggatgacgagctcatcatcgacttcgac
aatttcgtccggtgtctggttcgactggaaacactgttcaggatatttaagcagctggac
cccgagggctctggaaccatagagctggacctcatctcttggctctgcttttccgtcctc
taa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (7)   
   KEGG PATHWAY (7)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (5)   
   RefSeq(pep) (5)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (6)   
   Pfam (6)   
All databases (43)   

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