KEGG   Canis lupus familiaris (dog): 483186
Entry
483186            CDS       T01007                                 
Symbol
SETDB1
Name
(RefSeq) histone-lysine N-methyltransferase SETDB1 isoform X3
  KO
K11421  [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase [EC:2.1.1.366]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa00310  Lysine degradation
cfa01100  Metabolic pathways
cfa04550  Signaling pathways regulating pluripotency of stem cells
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    483186 (SETDB1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    483186 (SETDB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:cfa03036]
    483186 (SETDB1)
Enzymes [BR:cfa01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.366  [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase
     483186 (SETDB1)
Chromosome and associated proteins [BR:cfa03036]
 Eukaryotic type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     483186 (SETDB1)
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    483186 (SETDB1)
SSDB
Motif
Pfam: DUF5604 Tudor_4 MBD SET Tudor_5 Pre-SET DUF4537 53-BP1_Tudor Chromo
Other DBs
NCBI-GeneID: 483186
NCBI-ProteinID: XP_005630828
Ensembl: ENSCAFG00000023501
VGNC: 46060
UniProt: A0A8C0SCA0 A0A8I3PJ60
Position
17:59481019..59513690
AA seq 1294 aa
MSSLPGCIGLDAATAAVESEEIAELQQAVVEELGISMEELRQFIDEELEKMDCVQQRKKQ
LAELETWVIQKESEVAHVDQLFDDASRAVTNCESLVKDFYSKLGLQYRDSSSEDETSRPT
EIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDL
HKGTLSQMSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPGKKYKVKFDNKGKS
LLSGNHIAYDYHPPADKLFVGSRVVAKYKDGNQVWLYAGIVAETPNVKNKLRFLIFFDDG
YASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYITAYPNRPMVLLKSGQLIKTEWEG
TWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASALEKKHGGQLRTR
PNMGAVRSKGPVVQYTQDLASTGTQFKPVEPPQPTAPPAPPIPPAPPVPPLSPQAGDNDS
LESQLAQSRKQVAKKSTSFRPGSVGSGHSSPTSPALSENVPAGKPGSNQTYRSPLGSTAS
ASAAPPAPPAPPAFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRVRPMRSAQYRGK
NPLLVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEM
FCLDPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGV
FINTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTG
VYECNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKIL
TDDFADKEGLEMGDEYFANLDHIESVENFKEGYESDAPCSSDSSGVDLKDQEDGNSGTED
PEESNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENGLSEIASKDSRPPDLGPPHI
PIPPVIPVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSRSSFKTSEGGEGRAGGG
RGEAEKASTSGLGFKEEGDIKQAKKEDPDDRSKMSVLTESSRNYGYNPSPMKLEGLRRPP
SKTSMHQSRRLMASAQSNTDDVLTLSSSTESEGESGTSRKPTTGQTSATAVDSDDIQTIS
SGSEADDFEDKKNMSGPTKRQVAVKSTRGFALKSTHGIAIKSTNMASVEKGESAPVRKNT
RQFYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRA
GTELTWDYNYEVGSVEGKELLCCCGAIECRGRLL
NT seq 3885 nt   +upstreamnt  +downstreamnt
atgtcctccctccctgggtgcattggtttggatgcagctacagctgcagtggagtctgaa
gagattgcagagctgcaacaagcagtggtcgaggagctgggtatctcaatggaggaactt
cggcagttcattgatgaagaactagaaaagatggactgtgtacagcagcgtaagaagcaa
ctagcagaattggaaacatgggtaatacagaaggaatctgaggtggcccatgtggaccag
ctctttgatgatgcatccagggcggtgactaactgtgagtctctggtgaaggacttttac
tccaaactgggactacaataccgggacagtagctctgaggatgaaacttcccggcctaca
gaaataatagagattcctgatgaagatgatgatgtcctcagtattgattcaggtgatgct
gggagcagaactcccaaagaccagaagctccgtgaagctatggctgccttaagaaagtca
gctcaggatgtccagaagttcatggatgctgtcaacaagaagagcagttcccaggatcta
cataaaggaaccttgagtcagatgtctggagaactgagcaaagatggtgacctgatagtc
agcatgcgcatcctgggcaagaagagaacaaagacatggcacaaaggcactcttattgcc
atccagacggttggaccaggaaagaagtacaaggtgaaattcgacaataaaggaaagagt
ctactgtcggggaaccatattgcctatgattaccaccctcctgctgacaagctgtttgtg
ggcagtcgagtggtggccaaatacaaggatgggaatcaggtctggctctatgctggcatt
gtagctgagacaccaaacgtcaaaaacaagctcaggtttctcattttctttgatgatggc
tatgcttcctatgtcacacagtctgagctatatcccatttgccggccattgaaaaagact
tgggaggacatagaagacatctcctgccgggacttcatagaggagtatatcacagcttac
cccaaccgccccatggtactgctaaagagtggccagcttatcaagactgagtgggaaggc
acatggtggaagtcccgggtcgaggaggtggacggcagcctagtcaggatcctcttcctg
gatgacaaaagatgtgaatggatctatcgaggctctacacggctggagcccatgttcagc
atgaagacatcctcagcctctgcattggagaagaagcatgggggacagctcaggacacgt
ccaaatatgggtgctgtcaggagcaaaggtcctgtggtccaatacacccaagatctggcc
agtactgggacccagttcaagccagtggagcccccacagcctacagctcctcctgccccc
cccatcccacctgccccacctgtaccccctctgtccccacaggcaggtgacaatgacagc
ttggaaagtcagcttgcccaatctcggaagcaggtagccaaaaagagcacatccttccga
ccaggatctgtgggctctggtcattcctcccctacctctcctgcactcagtgaaaatgtc
cctgctgggaaacctgggagcaaccagacatacagatcacctttaggctcaacagcctct
gcttcagcagcgccgccagcacctccagcacccccagctttccatggcatgctggagcgg
gccccagcagagccctcctaccgtgcccccatggagaagctcttctacttacctcatgtg
tgcagctacacatgtctgtctcgagtcaggcctatgagaagtgcacagtaccggggcaag
aatcctctgttggtcccactactctatgacttccggcgaatgacggcccgccgccgagtt
aaccgcaagatgggctttcatgttatctataagacaccctgtggcctctgccttcggaca
atgcaggagatcgaacgctatctttttgagactggctgtgacttcctcttcctggagatg
ttctgtttggatccatatgttcttgtggaccgaaagtttcaaccctataaaccattttac
tatattttggacatcacctatgggaaggaagatgttcccctatcctgtgttaatgaaatt
gacacaacccccccaccccaggtggcctacagtaaggaacgaatccctggcaagggtgtt
ttcattaacacaggcccagaatttctggttggttgtgactgcaaggatgggtgccgagac
aagtccaaatgtgcctgtcatcagctaactatccaggccacagcctgcaccccaggtggc
cagatcaaccctaactctggataccagtacaagagactagaagagtgtctacccacagga
gtttatgagtgtaacaaacgctgcaaatgtgacccaaacatgtgcacaaaccggttggtg
cagcatggactccaggttcgactacagctattcaagacacagaacaagggctggggaatc
cgctgcttggatgacattgccaaaggctcctttgtctgtatttatgcaggcaagatcctg
acagatgactttgcagacaaggagggcctggagatgggtgatgagtactttgccaatctg
gaccatatcgagagtgtggagaacttcaaggaaggatatgagagtgatgccccctgttct
tctgacagcagcggggtggacttgaaggaccaggaggatggcaatagtggtacagaggat
cctgaagagtctaacgatgacagctctgatgataacttctgtaaagatgaagacttcagc
accagctctgtgtggcgcagctatgctacccggcggcagacccggggtcaaaaggagaat
ggactgtctgagatagcttccaaggattcccgccccccagaccttggccccccacatatt
cctatccctccagtaatccccgtaggtggctgcaatccaccttcctctgaagagacaccc
aagaacaaggtggcctcatggttgagctgcaatagtgtcagtgaaggtggctttgctgac
tctgatagccgttcatccttcaagactagtgaaggtggggaaggccgggctgggggaggc
agaggggaagctgagaaggcctccacttcagggctgggcttcaaggaggagggagacatc
aagcaggccaagaaagaggatcccgatgaccgaagcaagatgtcagtacttactgaaagc
tctcgaaattatggttacaatccttcccccatgaagctcgaaggactccgccgcccacct
agtaagactagtatgcatcagagccgacgactcatggcctctgctcaatccaacactgat
gatgtcctaacactgtccagcagcacagaaagtgagggggaaagtgggaccagccggaaa
cccaccactggtcagacttcagccacagcagtggatagcgatgatatccagaccatctcc
tctggctcagaagcagatgactttgaggacaagaagaacatgtctggtccaacaaagcgc
caggtggcagtaaaatcaacccgagggtttgctcttaagtcaacgcatgggattgccatt
aaatcaaccaacatggcctctgtggaaaagggggagagtgcacctgttcgtaagaacaca
cgccagttctatgatggggaggagtcttgttatatcattgatgccaagctcgaaggcaac
ctgggccgctacctcaatcacagctgcagccccaacctgtttgtccagaatgtcttcgtg
gacactcatgatcttcgctttccctgggtggcgttctttgccagcaagaggatccgggct
gggaccgagctcacttgggactacaactacgaggtgggcagcgtggaaggcaaggagctg
ctctgctgctgtggggccatcgaatgcagagggcgtcttctttag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG ORTHOLOGY (1)   
   RefGene (17)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (27)   
   UniProt (2)   
   RefSeq(pep) (25)   
DNA sequence (25)   
   RefSeq(nuc) (25)   
Protein domain (9)   
   Pfam (9)   
All databases (97)   

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