KEGG   Canis lupus familiaris (dog): 483665
Entry
483665            CDS       T01007                                 
Symbol
INS
Name
(RefSeq) insulin precursor
  KO
K04526  insulin
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04010  MAPK signaling pathway
cfa04014  Ras signaling pathway
cfa04015  Rap1 signaling pathway
cfa04022  cGMP-PKG signaling pathway
cfa04066  HIF-1 signaling pathway
cfa04068  FoxO signaling pathway
cfa04072  Phospholipase D signaling pathway
cfa04114  Oocyte meiosis
cfa04140  Autophagy - animal
cfa04150  mTOR signaling pathway
cfa04151  PI3K-Akt signaling pathway
cfa04152  AMPK signaling pathway
cfa04211  Longevity regulating pathway
cfa04213  Longevity regulating pathway - multiple species
cfa04810  Regulation of actin cytoskeleton
cfa04910  Insulin signaling pathway
cfa04911  Insulin secretion
cfa04913  Ovarian steroidogenesis
cfa04914  Progesterone-mediated oocyte maturation
cfa04917  Prolactin signaling pathway
cfa04923  Regulation of lipolysis in adipocytes
cfa04930  Type II diabetes mellitus
cfa04931  Insulin resistance
cfa04932  Non-alcoholic fatty liver disease
cfa04940  Type I diabetes mellitus
cfa04950  Maturity onset diabetes of the young
cfa04960  Aldosterone-regulated sodium reabsorption
cfa05010  Alzheimer disease
cfa05215  Prostate cancer
cfa05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    483665 (INS)
   04014 Ras signaling pathway
    483665 (INS)
   04015 Rap1 signaling pathway
    483665 (INS)
   04066 HIF-1 signaling pathway
    483665 (INS)
   04068 FoxO signaling pathway
    483665 (INS)
   04072 Phospholipase D signaling pathway
    483665 (INS)
   04022 cGMP-PKG signaling pathway
    483665 (INS)
   04151 PI3K-Akt signaling pathway
    483665 (INS)
   04152 AMPK signaling pathway
    483665 (INS)
   04150 mTOR signaling pathway
    483665 (INS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    483665 (INS)
  09143 Cell growth and death
   04114 Oocyte meiosis
    483665 (INS)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    483665 (INS)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    483665 (INS)
   04910 Insulin signaling pathway
    483665 (INS)
   04923 Regulation of lipolysis in adipocytes
    483665 (INS)
   04913 Ovarian steroidogenesis
    483665 (INS)
   04914 Progesterone-mediated oocyte maturation
    483665 (INS)
   04917 Prolactin signaling pathway
    483665 (INS)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    483665 (INS)
  09149 Aging
   04211 Longevity regulating pathway
    483665 (INS)
   04213 Longevity regulating pathway - multiple species
    483665 (INS)
 09160 Human Diseases
  09162 Cancer: specific types
   05215 Prostate cancer
    483665 (INS)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    483665 (INS)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    483665 (INS)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    483665 (INS)
   04940 Type I diabetes mellitus
    483665 (INS)
   04950 Maturity onset diabetes of the young
    483665 (INS)
   04932 Non-alcoholic fatty liver disease
    483665 (INS)
   04931 Insulin resistance
    483665 (INS)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:cfa04052]
    483665 (INS)
Cytokines and neuropeptides [BR:cfa04052]
 Neuropeptides
  Neuropeptides (Unclassified)
   483665 (INS)
SSDB
Motif
Pfam: Insulin Ins_beta
Other DBs
NCBI-GeneID: 483665
NCBI-ProteinID: NP_001123565
Ensembl: ENSCAFG00000010092
VGNC: 97204
UniProt: P01321
Position
18:complement(44933843..44934720)
AA seq 110 aa
MALWMRLLPLLALLALWAPAPTRAFVNQHLCGSHLVEALYLVCGERGFFYTPKARREVED
LQVRDVELAGAPGEGGLQPLALEGALQKRGIVEQCCTSICSLYQLENYCN
NT seq 333 nt   +upstreamnt  +downstreamnt
atggccctctggatgcgcctcctgcccctgctggccctgctggccctctgggcgcccgcg
cccacccgagccttcgttaaccagcacctgtgtggctcccacctggtagaggctctgtac
ctggtgtgcggggagcgcggcttcttctacacgcctaaggcccgccgggaggtggaggac
ctgcaggtgagggacgtggagctggccggggcgcctggcgagggcggcctgcagcccctg
gccctggagggggccctgcagaagcgaggcatcgtggagcagtgctgcaccagcatctgc
tccctctaccagctggagaattactgcaactag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (30)   
   KEGG PATHWAY (30)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (2)   
   Pfam (2)   
All databases (45)   

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