KEGG   Canis lupus familiaris (dog): 484513
Entry
484513            CDS       T01007                                 
Symbol
PAK4
Name
(RefSeq) serine/threonine-protein kinase PAK 4 isoform X1
  KO
K05734  p21-activated kinase 4 [EC:2.7.11.1]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04012  ErbB signaling pathway
cfa04014  Ras signaling pathway
cfa04360  Axon guidance
cfa04510  Focal adhesion
cfa04660  T cell receptor signaling pathway
cfa04810  Regulation of actin cytoskeleton
cfa05170  Human immunodeficiency virus 1 infection
cfa05206  MicroRNAs in cancer
cfa05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    484513 (PAK4)
   04014 Ras signaling pathway
    484513 (PAK4)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    484513 (PAK4)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    484513 (PAK4)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    484513 (PAK4)
  09158 Development and regeneration
   04360 Axon guidance
    484513 (PAK4)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    484513 (PAK4)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    484513 (PAK4)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    484513 (PAK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cfa01001]
    484513 (PAK4)
Enzymes [BR:cfa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     484513 (PAK4)
Protein kinases [BR:cfa01001]
 Serine/threonine kinases: STE group
  STE20 family
   484513 (PAK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PBD Kinase-like ABC1 Pkinase_fungal hnRNP_Q_AcD RIO1 KIND Kdo
Other DBs
NCBI-GeneID: 484513
NCBI-ProteinID: XP_005616659
Ensembl: ENSCAFG00000005606
VGNC: 53528
UniProt: A0A8C0RM04
Position
1:complement(113410153..113453319)
AA seq 592 aa
MFGKKKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLVDPACIT
SIQPGAPKTIVRGSKGAKDGALTLLLDEFENMSVTRSNSLRRDSPPPPARARQENGMPAE
PASTARGAPEKAGSQGRAAGRSEAGGSSGDRRRVGPEKRPKSSREGSGGPQESSRDKRPL
SGPDVGTPQPAGLAGGARVAAGRPFNTYPRADTDHPARGAQGEPHNLAPNGPSAGGLAVP
QSSSSRPPTRARGPPSPGVLGPHASEPQLAPQARPIAAPAGPPAPGPPGPRSPQREPQRV
SHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGRLVAVKKMDLRKQQR
RELLFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAA
VCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTP
YWMAPELISRLPYGPEVDIWSLGVMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLH
KVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR
NT seq 1779 nt   +upstreamnt  +downstreamnt
atgtttgggaagaagaagaagcgagtagagatctccgcgccatccaacttcgagcaccgc
gtgcacacgggcttcgaccagcacgagcagaagttcacggggctgccccgccagtggcag
agcctgatcgaggagtcggctcggcggcccaagcccctggtggaccctgcctgcatcacc
tccatccagcccggggcccccaagaccatcgtgcgtggcagcaaaggcgccaaggatggg
gccctcacgctgctgctcgacgagtttgagaacatgtcggtgacgcgctccaactccctg
cggagagacagcccaccgccacctgcccgtgcccgccaggagaacgggatgcccgcagag
ccggccagcacggccagaggggccccagagaaggcgggcagccaaggccgggccgccggt
cgcagcgaggcgggtggcagcagtggcgacaggcggcgggtggggccagagaagaggccc
aagtcttccagggagggctcagggggaccccaagagtcctcccgggacaaacgccccctc
tctgggcctgacgtcggcacccctcaacctgccggtctggccggtggggccagagtggca
gctggtcggccctttaacacgtacccgagggccgatacggaccacccggcccggggtgcc
cagggggagcctcacaacctggcccccaacgggccttcggcagggggcctggcggtcccc
cagtcttcctcctcccggcctcccacccgagcccgcggtccccccagcccgggagtgctg
gggccccatgcctctgagccccagctggcccctcaggcccgccccattgctgcccctgcc
ggccccccggcccccgggccccctgggccccgctcgccacagcgggaaccccagcgagtg
tcgcacgagcagttccgggccgccttgcagctggtggtggaccccggcgaccctcgctcc
tacctggacaacttcatcaagatcggcgagggctccacgggcatcgtgtgcattgccacc
gtgcgcagctcgggccggctggtggccgtcaagaagatggacctgcgcaagcagcagagg
cgtgagctgctcttcaacgaggtggtgatcatgcgggactaccagcacgagaacgtggtg
gagatgtacaacagctacctggtcggggatgagctctgggtggtgatggagttcctggag
ggcggcgccctcaccgacatcgtcactcacaccaggatgaatgaggagcagattgccgcc
gtgtgcctggccgtgctgcaggccttgtctgtgctccacgcgcagggagtcatccaccgc
gacatcaagagtgactccatcctgctgacccacgacggcagagtgaagctgtcggacttt
gggttctgcgcccaggtgagcaaggaggtaccacggaggaagtcactggtcggcacgccc
tactggatggccccagagctcatctctcgccttccctatgggccagaggtggacatctgg
tctctgggggtgatggtgatcgagatggtggatggggagcccccctacttcaacgagccc
cccctcaaagccatgaagatgattcgggacaacctgccaccccgactgaaaaacctgcac
aaggtgtcaccatccctgaagggcttcctggaccgcctgctggtgcgtgacccggcccag
cgggccacagcggctgaactgctgaagcacccgttcctggccaaagcgggcccacccgcc
agcatcgtgcccctcatgcgccagaaccgcaccagatga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (9)   
   KEGG PATHWAY (9)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   RefGene (19)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (18)   
   UniProt (1)   
   RefSeq(pep) (17)   
DNA sequence (17)   
   RefSeq(nuc) (17)   
Protein domain (10)   
   Pfam (10)   
All databases (84)   

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