KEGG   Canis lupus familiaris (dog): 486102
Entry
486102            CDS       T01007                                 
Symbol
PTK2B
Name
(RefSeq) protein-tyrosine kinase 2-beta isoform X1
  KO
K05871  focal adhesion kinase 2 [EC:2.7.10.2]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04020  Calcium signaling pathway
cfa04062  Chemokine signaling pathway
cfa04072  Phospholipase D signaling pathway
cfa04650  Natural killer cell mediated cytotoxicity
cfa04670  Leukocyte transendothelial migration
cfa04912  GnRH signaling pathway
cfa05135  Yersinia infection
cfa05161  Hepatitis B
cfa05163  Human cytomegalovirus infection
cfa05170  Human immunodeficiency virus 1 infection
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    486102 (PTK2B)
   04072 Phospholipase D signaling pathway
    486102 (PTK2B)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    486102 (PTK2B)
   04670 Leukocyte transendothelial migration
    486102 (PTK2B)
   04062 Chemokine signaling pathway
    486102 (PTK2B)
  09152 Endocrine system
   04912 GnRH signaling pathway
    486102 (PTK2B)
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    486102 (PTK2B)
   05161 Hepatitis B
    486102 (PTK2B)
   05163 Human cytomegalovirus infection
    486102 (PTK2B)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    486102 (PTK2B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cfa01001]
    486102 (PTK2B)
Enzymes [BR:cfa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     486102 (PTK2B)
Protein kinases [BR:cfa01001]
 Non-receptor tyrosine kinases
  FAK family
   486102 (PTK2B)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Focal_AT FERM_N_2 Pkinase FERM_C_FAK1 FERM_M Kinase-like FERM_F2 Haspin_kinase UCH
Other DBs
NCBI-GeneID: 486102
NCBI-ProteinID: XP_005635734
Ensembl: ENSCAFG00000008670
VGNC: 45159
UniProt: A0A8C0PBH0 A0A8I3RYS0
Position
25:complement(30723893..30850311)
AA seq 1009 aa
MSGVSEPLSRVKVGTLRHPQGPPESMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVK
CTVHTEIQEVIASILLSGRIGPNIQLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
LHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
EFKQIKSIRCLPLEEGQAILQLGIEGAPQSLSIKTSSLAEAENMADLVDGYCRLQGEHKG
SLIIHPKKDGEKRNSLPQIPMLNLEAQRPHLSESCSIESDIYAEIPDETLRRPGGPQYGV
TREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFLSEAVIMKN
LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
ENINCVHRDIAVRNILVASTECVKLGDFGLSRYIEDEEYYKASVTRLPIKWMSPESINFR
RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
CWDYDPSERPRFTELVCNLSDIYQMEKDIAIEQERNARYRPPKILEPTAYQEPPPKPSRP
KYRLPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR
EEDFIRPSSREEAQQLWEAERLKMRQILDKQQKQMVEDYQWLRQEEKSLDPMLYMNDKSP
LTPEKEAGYTEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLDLKNELCQ
LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
NT seq 3030 nt   +upstreamnt  +downstreamnt
atgtctggggtgtccgagcccctgagccgagtgaaggtgggcaccttacgtcatccccaa
ggccccccagagtccatggtggtggtgccagtagatgtggagaaggaagacgtgcggatc
ctcaaggtctgcttctatagcaacagcttcaaccctgggaagaactttaagctggttaaa
tgcactgtgcacaccgagatccaggaggtcattgcctccatcctgctgagcggacggatc
gggcccaacatccagctggctgagtgctatgggctgaggctgaagcacatgaagtcggat
gagatccattggttgcacccgcagatgacagtgggtgaggtgcaggacaagtacgagtgt
ctgcatgtggaagccgagtggaggtatgatcttcaaatccgctacttgccagaggacttc
atggaaagcctaaaagaagacaggacaacgctactgtatttttaccaacagctacggaat
gactacatgcaacgctatgccagcaaggtcagcgagggcatggccctgcagctaggctgt
ctggagctcaggcggttcttcaaggacatgcctcacaatgcacttgacaaaaagtccaac
tttgagctcctggagaaggaagtgggactggacctatttttcccaaagcagatgcaggag
aacttaaagcccaagcagttccggaagatgatccagcagacgttccagcagtatgcgtcg
ctcagggaggaggagtgcgtcatgaagttcttcaacaccctcgcaggctttgccaacatc
gaccaggagacctatcgctgtgaactcattcaaggatggaacattactgtggacctagtc
atcggccctaagggcatccgccagctgacaagtcaagatgcaaagcccacctgcctggcc
gaattcaagcagatcaagtccatcaggtgcctccctctggaggagggccaggcaatactg
cagctgggtattgaaggcgccccccagtccttgtccatcaaaacctcctctctggcagag
gccgagaacatggctgacctggtggacggttactgccggctgcagggggagcacaaaggc
tctctcatcattcatcccaagaaagatggtgagaagcggaacagcctgccccagatcccc
atgctaaacctggaggcgcagcggccccacctgtcagagagctgcagcatagaatcagac
atctatgcagagattcccgatgagacccttcgaaggcctggaggcccgcagtatggtgtc
acacgggaagatgtggtcctgaatcggattcttggtgaaggcttttttggggaggtctat
gaaggtgtctacacaaatcacaaaggggagaaaatcaatgtagctgtaaagacctgcaag
aaggactgcactctggacaacaaggagaagttcctgagtgaggcagtgatcatgaagaat
ctcgaccacccgcatattgtgaaactgatcggcatcattgaagaggagcccacctggatc
atcatggaattgtatccctacggtgagctgggccactacctggagaggaacaagaactcc
ctgaaggtgctcaccctcgtcctgtactcattgcagatttgcaaggccatggcctacctg
gagaacatcaactgtgtccacagggacatcgccgtccgaaacatcctggtggcctccact
gagtgtgtgaagctgggcgactttggcctttcccggtacattgaggatgaggagtactac
aaagcctctgtgactcgtcttcccatcaagtggatgtcccctgagtccatcaacttccgc
cgctttacgacagccagtgatgtctggatgttcgctgtatgcatgtgggagatcctgagc
tttggcaagcaacccttcttctggctggagaacaaggatgtcattggggtgctcgagaaa
ggggaccggctgcccaagcccgacctctgcccacctgttctctacacccttatgactcgc
tgctgggactacgaccccagtgagaggccacgcttcactgagctcgtgtgcaacctcagt
gacatttatcagatggagaaggacattgctatagagcaggagaggaatgctcgctaccga
cctcccaaaatcttggagcccacagcctaccaggaacccccacctaagcccagccggcct
aagtacagactccctccacaaaccaacctcttggctcccaagctacagttccaggtccct
gagggtctgtgtgccagctcacctacgctcaccagccctatggagtatccatctcctgta
aactcgctgcataccccacctctccaccggcacaatgtcttcaagcgccacagcatgcgg
gaggaggacttcatccgacccagcagccgagaagaagctcagcagctatgggaggccgag
aggctcaagatgagacagatcctggacaagcagcagaagcagatggtggaagattaccag
tggctgaggcaggaggagaaatccttggaccccatgttgtacatgaacgataagtcccca
ctgaccccagagaaggaggctggctacacggagttcacgggtcccccacagaagccacca
cggctgggcgcgcagtccatccagcccacagccaacctggaccggaccgatgacctggtg
tacctcaatgtcatggagctagtgcgggctgtgttggatctcaagaatgagctctgccag
ctgcctcctgaaggctacgtggtggtggtgaagaacgtgggcctgaccctgcggaagctc
attgggagtgtggatgatctcctgccctccttgccgtcatcctctcggacagagattgag
gggacccagaaactgctcaacaaggatctagcagagctcatcaataagatgcgcctcgcc
cagcaaaatgccgtgacctccctgagcgaggagtgcaagcggcagatgctcacagcctcc
cacaccctggccgtggacgccaaaaacctgctcgatgccgtagaccaggccaaagttctg
gccaatctggcccacccgcctgcagagtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (10)   
   KEGG PATHWAY (10)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (22)   
   UniProt (2)   
   RefSeq(pep) (20)   
DNA sequence (20)   
   RefSeq(nuc) (20)   
Protein domain (10)   
   Pfam (10)   
All databases (81)   

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