KEGG   Canis lupus familiaris (dog): 486962
Entry
486962            CDS       T01007                                 
Symbol
CYP7A1
Name
(RefSeq) cytochrome P450 7A1 isoform X2
  KO
K00489  cholesterol 7alpha-monooxygenase [EC:1.14.14.23]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa00120  Primary bile acid biosynthesis
cfa00140  Steroid hormone biosynthesis
cfa01100  Metabolic pathways
cfa03320  PPAR signaling pathway
cfa04976  Bile secretion
cfa04979  Cholesterol metabolism
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00120 Primary bile acid biosynthesis
    486962 (CYP7A1)
   00140 Steroid hormone biosynthesis
    486962 (CYP7A1)
 09150 Organismal Systems
  09152 Endocrine system
   03320 PPAR signaling pathway
    486962 (CYP7A1)
  09154 Digestive system
   04976 Bile secretion
    486962 (CYP7A1)
   04979 Cholesterol metabolism
    486962 (CYP7A1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:cfa00199]
    486962 (CYP7A1)
Enzymes [BR:cfa01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.23  cholesterol 7alpha-monooxygenase
     486962 (CYP7A1)
Cytochrome P450 [BR:cfa00199]
 Cytochrome P450, animal type
  CYP7 family
   486962 (CYP7A1)
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 486962
NCBI-ProteinID: XP_038316784
Ensembl: ENSCAFG00000007098
VGNC: 50378
Position
29:complement(9598242..9625248)
AA seq 498 aa
MDKWMLKLFNWKMNLCGYFLENVRQMGEPPLENGLIPYLGCALKFGANPLEFLRANQRKY
GHVFTCRLMGNYVHFITNPLSYQKVLCHGKYLDWKKFHFTTSAKAFGHRSIDPSDGNTTE
NINKTFIKTLQGDALNSLTEAMMENLQLVMRCPLVSKSKTPAWVTEGMYSFCYRVMFEAG
YLTLFGKDLTGQDAQKGLILNNLDHFKEFDKIFPALVAGLPIHVFKTAHHAREKLAEGLR
HENLGKRDHISELVRFLNDMLSTLDDMDKAKTHLAILWASQANTIPATFWSLFQMIRSPE
AMKAATEEVNKTLENAGQKISLDGSPICLNQMQLNDMPVLDSLIKESLRLSSASLNIRTA
TEDFTLHLQDSSYNIRKDDIIAFYPQLVHLDPEIYPDPLTFKYDRYLDENGKTKTTFYSN
GIKLKYYYMPFGSGATMCPGRLFAVQEIKQFLILMLSYFELELVESQVKCPPLDQSRAGL
GILPPLNDIEFKYKFKHL
NT seq 1497 nt   +upstreamnt  +downstreamnt
atggataaatggatgcttaaactgtttaattggaagatgaacttatgtggatactttctt
gagaatgttagacaaatgggtgaaccaccgctggagaatgggttgattccatacctggga
tgtgctttgaaatttggtgccaatcctctcgagttcctgagagcaaatcaaaggaaatat
ggtcatgtttttacctgcagattgatgggaaactatgtccacttcatcacaaatcccttg
tcataccagaaagtgttgtgccatggaaaatacttggattggaaaaagtttcactttact
acttctgcaaaggcatttgggcacagaagcattgacccaagtgatggaaataccactgaa
aatataaataaaactttcatcaaaaccctgcagggcgatgccttgaattccctcacagaa
gccatgatggaaaacctccaacttgtcatgagatgtcccctggtatctaaatcaaagact
cctgcctgggtgacggaagggatgtattccttctgttaccgagtgatgtttgaagctggg
tatttaactctctttggcaaagatcttacagggcaagatgcacaaaaaggacttattctg
aataaccttgaccacttcaaggaatttgacaaaatctttcctgctctggtagcaggcctc
cccattcatgtgttcaagacggcacaccacgctagggaaaagctggcagagggcttgagg
catgagaaccttggaaagagagaccacatctcggaactggtcaggtttctgaatgacatg
ctttccaccttagatgacatggataaggctaagacgcacctcgctatcctctgggcatca
caagcaaacactattccagcgaccttctggagcttatttcaaatgattaggagccctgaa
gcaatgaaagcagctactgaagaagtgaataaaacactagagaatgctggccaaaaaatc
agccttgatggcagtcctatttgtctgaatcaaatgcaactgaatgacatgccagtgcta
gatagcctcatcaaggagtctctgaggctttccagtgcctccctgaacatccggactgct
acagaggattttactttgcacctccaggacagttcctataacatccgcaaagatgacatc
atagctttttatccgcagttagtgcatttagatccagaaatctacccagaccctttgact
tttaaatatgatcggtatcttgatgaaaatgggaagacaaagaccaccttctatagtaac
ggaatcaagttaaagtattactacatgccttttgggtcaggagcgacaatgtgtcctgga
agattatttgctgtccaggaaatcaagcagtttttgattctgatgctttcctattttgaa
ctagagcttgtagagagccaagtcaaatgtccccctttggaccagtcccgtgcaggctta
ggcattttaccaccattaaatgatatcgagtttaaatataaattcaaacatttgtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (10)   
   KEGG COMPOUND (10)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (15)   
   RefSeq(pep) (15)   
DNA sequence (15)   
   RefSeq(nuc) (15)   
Protein domain (1)   
   Pfam (1)   
All databases (71)   

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