KEGG   Canis lupus familiaris (dog): 487221
Entry
487221            CDS       T01007                                 
Symbol
PDE4D
Name
(RefSeq) cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X3
  KO
K13293  cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa00230  Purine metabolism
cfa01100  Metabolic pathways
cfa04024  cAMP signaling pathway
cfa04928  Parathyroid hormone synthesis, secretion and action
cfa05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    487221 (PDE4D)
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    487221 (PDE4D)
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    487221 (PDE4D)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    487221 (PDE4D)
Enzymes [BR:cfa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.53  3',5'-cyclic-AMP phosphodiesterase
     487221 (PDE4D)
SSDB
Motif
Pfam: PDEase_I PDE4_UCR
Other DBs
NCBI-GeneID: 487221
NCBI-ProteinID: XP_003433851
Ensembl: ENSCAFG00000007100
VGNC: 44355
UniProt: A0A8C0LUJ9 A0A8I3N1Y7
Position
2:complement(42920230..44321074)
AA seq 746 aa
MAQQTTSPDTLTVPDVDNPHCPNPWLNEDLVKSLRENLLQQEKSKPARKSVSPKLSPVIS
PRNSPRLLRRMLLSSNIPKQRRFTVAHTCFDVDNGTSAGRSPLDPMTSPGSGLILQANFV
HSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAAL
TNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEM
ASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQ
ISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVI
MHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPAL
EAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLL
QEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLD
NYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKH
NASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDEQ
EEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQ
VEEETVGEEENSQPEACVIEDHSPDT
NT seq 2241 nt   +upstreamnt  +downstreamnt
atggcccagcagacgacgagcccggacaccctaacagtccccgacgtggataatccgcat
tgtccgaacccctggctcaacgaggatcttgtgaaatccttgcgggagaacctgttgcag
caggagaagtccaagccggcgaggaaatcggtctcccccaagctctctccagtaatttct
ccgaggaattccccgaggctcctgcggaggatgcttctcagcagcaacatccccaaacag
cggcgtttcacggtggcacatacgtgttttgatgtggacaatggcacatctgcgggacgg
agtcccttggatcccatgaccagcccaggatctgggctaattctccaagcaaactttgtc
cacagtcaacgtcgtgagtcctttctgtatcgatccgacagcgattatgacctgtctcca
aagtctatgtcccggaactcctccattgccagtgatatacatggagatgacttgattgtg
accccatttgctcaggtcttggccagcctgcgaactgtacgaaacaactttgctgcatta
actaatttgcaagatcgagcacctagcaaaagatcacccatgtgcaaccaaccatccatc
aacaaagccaccattacagaggaggcctaccagaaactggccagcgagaccctggaggag
ctggactggtgtctggaccagctggagaccctgcagaccaggcactccgtcagtgagatg
gcctccaacaagtttaaaaggatgcttaatcgggaactcacccatctctcggaaatgagt
cggtctggaaatcaagtgtcagagtatatatcaaatacattcttagataagcagcatgaa
gtagaaattccttctccaactcagaaggaaaaggagaaaaagaaaaggccaatgtctcag
atcagtggggtcaagaagttgatgcatagctccagtttgacgaattcaagcatcccgagg
tttggggttaaaactgaacaagaggatgtccttgccaaggaactagaagatgtgaacaaa
tggggtcttcatgttttcagaatagcagagctgtctggtaaccggcctttgactgttatc
atgcatactatttttcaggaacgggatttgttaaaaacatttaaaattccagtagacact
ttaattacataccttatgaccctggaagaccattaccatgctgatgtggcctaccacaac
aatattcatgctgcagatgtggtccagtcaacacatgtgctgttatctacacctgccttg
gaggctgtgtttacagatttggagattcttgcagcaatttttgccagtgcaatacatgat
gtagatcatcctggtgtgtcaaatcagtttctgatcaatacaaactctgaacttgccttg
atgtacaatgattcttctgtcttggaaaaccatcatttggccgtgggctttaagttgctt
caggaagaaaactgtgatattttccagaatttgaccaaaaagcaaagacaatcattaagg
aagatggtcattgacatcgttcttgcaacagacatgtcaaaacacatgaatctactggct
gatttgaagactatggttgaaactaagaaagtgacaagttctggagttcttcttctggat
aattattctgataggattcaggtccttcagaatatggtgcactgtgcagacctgagcaac
cccacaaagcctctccagctgtatcgccagtggactgaccgcataatggaggagttcttc
cgccaaggagaccgagagagggagcggggcatggagataagtcctatgtgtgacaagcac
aatgcatctgtggaaaaatcacaggtgggcttcatagactatattgttcatcctctctgg
gagacttgggcagacctcgtgcaccctgacgcccaggacattctggacactttggaggac
aatcgtgaatggtaccagagcacaattcctcagagcccctcgccggcaccagatgagcag
gaggaaggcaggcagggtcaaaccgagaagttccaatttgagctaactttagaggaggac
ggcgagtccgacaccgaaaaggacagtggaagtcaggttgaagaagacactagctgcagt
gactccaagaccctctgtactcaagactcggagtctaccgagatcccccttgatgagcaa
gtggaagaggagacagtaggggaagaagaaaacagccagcccgaagcctgcgtaattgaa
gaccattctcctgacacgtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (5)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG ORTHOLOGY (1)   
   RefGene (17)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (111)   
   UniProt (2)   
   RefSeq(pep) (109)   
DNA sequence (109)   
   RefSeq(nuc) (109)   
Protein domain (2)   
   Pfam (2)   
All databases (258)   

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