KEGG   Canis lupus familiaris (dog): 487512
Entry
487512            CDS       T01007                                 
Symbol
PLA2G4B
Name
(RefSeq) cytosolic phospholipase A2 beta
  KO
K16342  cytosolic phospholipase A2 [EC:3.1.1.4]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa00564  Glycerophospholipid metabolism
cfa00565  Ether lipid metabolism
cfa00590  Arachidonic acid metabolism
cfa00591  Linoleic acid metabolism
cfa00592  alpha-Linolenic acid metabolism
cfa01100  Metabolic pathways
cfa04010  MAPK signaling pathway
cfa04014  Ras signaling pathway
cfa04072  Phospholipase D signaling pathway
cfa04217  Necroptosis
cfa04270  Vascular smooth muscle contraction
cfa04370  VEGF signaling pathway
cfa04611  Platelet activation
cfa04664  Fc epsilon RI signaling pathway
cfa04666  Fc gamma R-mediated phagocytosis
cfa04724  Glutamatergic synapse
cfa04726  Serotonergic synapse
cfa04730  Long-term depression
cfa04750  Inflammatory mediator regulation of TRP channels
cfa04912  GnRH signaling pathway
cfa04913  Ovarian steroidogenesis
cfa04921  Oxytocin signaling pathway
cfa05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    487512 (PLA2G4B)
   00565 Ether lipid metabolism
    487512 (PLA2G4B)
   00590 Arachidonic acid metabolism
    487512 (PLA2G4B)
   00591 Linoleic acid metabolism
    487512 (PLA2G4B)
   00592 alpha-Linolenic acid metabolism
    487512 (PLA2G4B)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    487512 (PLA2G4B)
   04014 Ras signaling pathway
    487512 (PLA2G4B)
   04370 VEGF signaling pathway
    487512 (PLA2G4B)
   04072 Phospholipase D signaling pathway
    487512 (PLA2G4B)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    487512 (PLA2G4B)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    487512 (PLA2G4B)
   04664 Fc epsilon RI signaling pathway
    487512 (PLA2G4B)
   04666 Fc gamma R-mediated phagocytosis
    487512 (PLA2G4B)
  09152 Endocrine system
   04912 GnRH signaling pathway
    487512 (PLA2G4B)
   04913 Ovarian steroidogenesis
    487512 (PLA2G4B)
   04921 Oxytocin signaling pathway
    487512 (PLA2G4B)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    487512 (PLA2G4B)
  09156 Nervous system
   04724 Glutamatergic synapse
    487512 (PLA2G4B)
   04726 Serotonergic synapse
    487512 (PLA2G4B)
   04730 Long-term depression
    487512 (PLA2G4B)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    487512 (PLA2G4B)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    487512 (PLA2G4B)
Enzymes [BR:cfa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.4  phospholipase A2
     487512 (PLA2G4B)
SSDB
Motif
Pfam: PLA2_B cPLA2_C2 C2 DUF6527
Other DBs
NCBI-GeneID: 487512
NCBI-ProteinID: NP_001191165
Ensembl: ENSCAFG00000009735
UniProt: A0A8P0SER8
Position
30:8925947..8935469
AA seq 784 aa
MALAKVPGTCLLTVRVLQAHGLPSKDLVTPSDCYVSLWLPTASSHRLQTRTVKNCRNPIW
NQSFRFRIHSQLKNVLQLQVFDQDLLTSDDPMLSVLFDVGTLQAGEFRRESFSLNPQGEE
RLEVEFRLQRLTDCAEQLVSNGILVARELSCLHVRLEETGNQKQSEGRVQLVVPGSCEGS
QDASVGAGSFCFHCPACWEQELGILLQDAPREQLKVPLRALPSGQVVRLVFPTSQEPLMR
VELRKEEGPRELAVRLGCGPCAEEQAFLSRRKRVVARALKQVLQLGEDLQEDEIPVVAVM
ATGGGIRAMVSLYGQLAGLRELGLLDCISYITGASGSTWALANLYEDPEWSQKDLAGPTE
SLKTQVTKSKLGVLSPSQLQRYHRELGERARLGHPACFTNLWALICEALLHDEPHNHTLS
DQREALSHGQNPLPIYCALNTKEKKLSTFEFGEWCEFSPYEVGFPKYGAFIPSELFGSEF
FMGRLTKRLPESRICFLEGIWSNLYAANLQDSLYWASDPSQFWDRWAQDQANLDKEQVPL
LKIEEPPTGTGRIVEFFTDLLTRRPLAQATHNFLHGLHFHKDYFQHPYFSTWKATKLDGL
PNQLTPAEPHLCLLDVGYLINTSFPPLLRPTRDVDLILSLDYNLQGAFQQLQLLGRWCQE
QGIPFPPISPSVGEQQQPGECHSFLDPDCPEAPAVLHFPLVDDSFQEYSAPGIRRTPEEK
AAGEVNLSSSDSPYHYSKVTYSPEDMDKLLRLTHYNICNNREQLLEALRAAVQRRRERRQ
RHPQ
NT seq 2355 nt   +upstreamnt  +downstreamnt
atggctctggcaaaggttcctgggacctgcctgctcaccgttcgtgtcctacaggcccat
ggcctgccctcgaaggacttagtgaccccctctgactgctacgtaagcctttggctgccc
acagcctctagccacaggctccagactcgcacagtcaagaactgcagaaatcccatctgg
aatcagagctttcgctttcgaatccatagccagctcaagaatgtcttacagctgcaagtc
tttgaccaggaccttctgaccagtgatgaccccatgttgtcagtgctgtttgacgtgggg
actttgcaggctggggagttccgccgagagagcttctcactgaaccctcagggcgaggag
cggctagaagttgaatttcggctgcagagactgacagactgtgccgagcagcttgtcagc
aatggcatcctggtggcccgggagctctcctgcttgcacgttcgactggaggagacaggg
aaccagaaacagtcagagggcagagttcaacttgtggttcctgggtcctgtgagggttca
caggatgcctccgtgggtgccggctccttctgcttccattgcccagcctgctgggagcag
gagctgggtattcttctgcaggatgcccctcgcgagcaactgaaggtgcccctcagggcc
ttgccctctggccaagtggtgaggcttgtcttccctacatcccaggagcccctgatgagg
gtggagctgaggaaagaagaaggaccgagggagctggccgtgcgtctaggctgcggaccg
tgtgccgaggagcaggccttcctgagccggaggaagcgggtggtggccagagccctgaag
caggtcctgcagctgggtgaagacctgcaggaggatgagattccagtggtagcagttatg
gccactggcggtgggatccgggcgatggtttccctctatggacagctggctggactgagg
gagctgggtctcttggattgcatctcctatatcacaggggcctcaggctccacctgggct
ttggccaacctctacgaggacccggaatggtctcagaaggacctggcagggccgaccgag
tcactgaagacacaggtgaccaagagcaagttgggtgtactctctcccagccagctgcag
cggtaccaccgggagctgggggagcgtgcccgcctgggccacccggcctgcttcaccaac
ctgtgggccctcatctgcgaggcactgctgcacgatgagccccataaccacacactctca
gaccagcgagaggccctgagtcacggccagaaccctctgcccatctactgtgcccttaac
accaaggagaagaagctgagcacctttgaatttggagagtggtgtgagttctccccctat
gaggttggctttcccaagtatggtgccttcatcccctctgagctcttcggctctgagttc
ttcatggggcgcctgaccaagcggcttcctgagtcccgaatctgcttcctcgaaggtatc
tggagcaacctatatgcagccaacctccaggatagtttatactgggcctcagaccccagt
cagttctgggaccgctgggcacaggatcaggccaacctggacaaggagcaggtccctctt
ctaaagatagaagagcctcccactgggactggcaggattgttgagtttttcactgacctt
ctgacgcggcgcccactggcccaggccacccacaatttcctgcatggcctccatttccac
aaggactacttccaacatccttacttctctacctggaaagccaccaaactggatgggctc
cccaaccagctgacacctgcagagccccacctttgcctgctggatgttggctaccttatc
aacaccagcttcccgcccctactgcggcccacacgggacgtggacctcatcctgtcgctg
gattacaacctccaaggagcctttcagcaactgcagctcctgggccggtggtgccaggag
cagggcatcccgttcccacccatctcacccagcgttggagagcagcagcagccaggagag
tgccactcgtttttggacccagactgccccgaggccccagctgtgctgcacttccctcta
gtggatgactccttccaggagtactcggcccctggcatccggcgcacaccagaggaaaag
gcggcgggggaggtgaacctatcttcctccgactccccctaccactactccaaggtgacc
tacagcccagaggacatggacaagctgctgcgcctgacccactacaacatctgcaacaac
cgggagcagctgctagaggccctgcgtgcggctgtgcagcggaggcgggagcgcaggcag
cgccacccccagtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (23)   
   KEGG PATHWAY (23)   
Chemical substance (14)   
   KEGG COMPOUND (14)   
Chemical reaction (8)   
   KEGG ENZYME (1)   
   KEGG REACTION (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (16)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (4)   
   Pfam (4)   
All databases (79)   

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