KEGG   Canis lupus familiaris (dog): 489094
Entry
489094            CDS       T01007                                 
Symbol
NSD1
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-36 specific isoform X1
  KO
K15588  [histone H3]-lysine36 N-dimethyltransferase NSD1 [EC:2.1.1.357]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa00310  Lysine degradation
cfa01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    489094 (NSD1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:cfa03036]
    489094 (NSD1)
Enzymes [BR:cfa01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.357  [histone H3]-lysine36 N-dimethyltransferase
     489094 (NSD1)
Chromosome and associated proteins [BR:cfa03036]
 Eukaryotic type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     489094 (NSD1)
SSDB
Motif
Pfam: PWWP SET C5HCH AWS PHD PHD_2 MUM1-like_PWWP
Other DBs
NCBI-GeneID: 489094
NCBI-ProteinID: XP_005619221
Ensembl: ENSCAFG00000016473
VGNC: 43980
UniProt: A0A8C0RBH9 A0A8I3NH50
Position
4:complement(36025606..36179354)
AA seq 2698 aa
MDQTCELPRRNCLLPFSNPVNLDAPEDKDSPFGNGQSNFSEPLNGCTMQLSTASGTSQNA
YGQDSPSCYIPLRRLQDLASMINVEYLNGSADGSESFQDPEKSDSRAQSPVVCTSLSPGG
PTALAMKQEPSCNNSPELQVKVTKTIKNGFLHFENFTCVDDADVDSEMDPEQPVTEDESI
EEIFEETQTNAICNYEPKSENGVDVAMGNEQDSTPESRHGAVKSPFLPLAPQTETQKNKQ
RNEVDGSNEKAALLPAPFALGDTNVTIEEQLNSINLSFQDDPDSSTSTLGNMLELPGTSS
SSTSQELPFCQPKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMKVSNRRP
YRQYYVEAFGDPSERAWVAGKAIVMFEGRHQFEELPVLRRRGKQKEKGYRHKVPQKILSK
WEASVGLAEQYDVPKGSKNRRCVSSSIKLDSEEDMPFEDCTNDPESEHDLLLNGCLKSLA
FDSEHSADEKEKPCAKSRARKSSDNPKRTSMKKGHMQFEAHKEERRGKIPENLGLSFISG
DVSDKQASNELSRIANSLTGSNTAPGSFLFSSCGKNTAKKEFETSNCDSLLGLSEGALIS
KHSEEKKKLQRGLMCSSKVQLCYIGAGDEEKRSDSISICTTSDDGSSDLDPIDNSSESDN
SVLEITDAFDRTENMLSVQKNEKVKYTRYPATNTKVKAKQKSLITNSHTDHLMDCAKTVE
PGTETSQVNLSDLKVSAVVRKPQSDFRNDSFSPKFNTPSSISSENSLIKSGATNQALLHA
KSKQPKIRSIKCKHKENPVVVEPPVTNEDCSLKCCSSDTKGSPLASISKSGKVDGLKLLS
NMHEKTRDSNDIETAVVKHVLSELKELSYRSLSEDVSDSGTSKPSKPLLFSSASGQNHIP
IEPDYKFSTLLMMLKDMHDSKTKEQRLMTAQNLVSYRSPGLGDCSSSSPVSASKVLVSGS
STHSSEKNGDGTQKSVRPSPSGGDSALSGELSVPVPGLVSDRRDVPASSKSHSDCVTRRN
CGRSKPSSKLRDSFAAQMGRNTLNRKALKTERKRKLSRLPAVTLEAALQGDRVSGDSENG
SSRGGLEDSGKEEPLQLMGHLTSEDSAHFSSVHFDNKVNHPDPDKIPEKGPSFENRKGPE
LDNEMNSENDEPSGVNQAVPKKRWQRLNQRRTKPRKRTNRFREKENSEGAFGVLLPSDPV
KKGDEFPEHRPPTSTNVIEDTLADPNHTSCLDSIGPRLNVCDKSSASVEEMEKEPGIPSL
TPQPELPEPAVRSEKKRLRKPSKWLLEYTEEYDQIFAPKKKQKKVQEQVHKVSSRCEEES
LLARCRSSAQNKQVDENSLISTKEEPPVLEREAPFLEGPLAQSELGGGHAELPQLTLSVP
VAPEVSPRPILESEELLVKTPGNYESKRQRKPTKKLLESNDLDPGFMPKKGDLGLSKKCY
EAGHLENDSESRAASREYGGGAAKIFDKPRKRKRQRHATAKVHCKKMKNDDSSKETPGSE
GELMTHRTAASPKETVEESVENDHGMPASKKLQGERGGGAALKENVCQNCEKLGELLLCE
AQCCGAFHLECLGLTEMPRGKFICNECRTGIHTCFVCKQSGEDVKRCLLPLCGKFYHEEC
VQKYPPTVMQNKGFRCSLHICITCHAANPASVSASKGRLMRCVRCPVAYHANDFCLAAGS
KILASNSIICPNHFTPRRGCRNHEHVNVSWCFVCSEGGSLLCCDSCPAAFHRECLNIDIP
EGNWYCNDCKAGKKPHYREIVWVKVGRYRWWPAEICHPRAVPSNIDKMRHDVGEFPVLFF
GSNDYLWTHQARVFPYMEGDVSSKDKMGKGVDGTYKKALQEAAARFEELKAQKELRQLQE
DRKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATDDNPCGIDSECINRMLLYE
CHPTVCPAGGRCQNQCFTKRQYPEVEIFRTLQRGWGLRTKTDIKKGEFVNEYVGELIDEE
ECRARIRYAQEHDITNFYMLTLDKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTR
VGLFALSDIKAGTELTFNYNLECLGNGKTVCKCGAPNCSGFLGVRPKNQPIATEEKSKKF
KKKQQGKRRTQGEITKEREDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRPAGKWEC
PWHQCDICGKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIR
EYVPPPVPLPPGPGTHLAEHSSGVAAQGPKMLDKLPADTNQTLSLSKKALAGTCQRPLLP
ERPPDRTDSRPQPVDRVRDLAGSGTKPQSLVSSQKPLDRPPAVAGPRPLLSDKPSPVTGI
SSSPSVRSQSLERPLGTADPRLDKSIGAASPRPQSLEKTPGPPGLRLPPPDRLLVTSSPK
PQTSDRPPDKSHASLSQRLPPPDKVLSAVVQTLVAKEKALRPVDQNTQSKNRAALVMDLI
DLTPHQKERAASPHEVTPQVDEKMPVLESSSWTASKGLGQMPRAVERGSMSDPVLQPPGK
TAVPSEHPWQAVKSLTQARLLSQPSAKAFLYEPTTQASGRAPAGVEQIPGPPSQAPGLVK
QVKQMTGGQQLPGLAAKSGQSFRPLGKAPSTLCTEEKKLATAEQSPWALGKSSPGPGLWP
MVAGQTISPSCWSSGNTQTLAQTCWSLGRGQDPKPEQNTLPALNQAPSSHKCAESEQK
NT seq 8097 nt   +upstreamnt  +downstreamnt
atggatcagacctgtgaactacctagaagaaattgtctgctgcccttttccaatccagtg
aatttagatgcccctgaagacaaggacagccctttcggtaatggtcaatccaatttttct
gagccacttaatgggtgtactatgcagttatcgactgccagtggaacatcccaaaatgct
tatggacaagattctccatcttgttacattccactgcggagactacaggatttggcctcc
atgatcaatgtagagtatttaaatgggtctgctgatggatcagaatcctttcaagaccct
gaaaaaagtgattcaagagctcagtcgccagttgtttgcacttccttgagtcctggtggt
ccaacagcacttgctatgaaacaggaaccctcttgtaataactcccccgaactccaggta
aaagtaacaaagactatcaagaatggctttctgcactttgagaattttacttgtgtggac
gatgcagatgtagattctgaaatggacccagaacagccagtcacagaggatgagagtata
gaggagatctttgaggaaactcagaccaatgccatctgcaattatgagcctaaatcagag
aatggtgtagacgtggccatgggaaatgaacaagacagcacaccagagagtagacatggt
gcagtcaaatcgccattcttgccattagctcctcaaactgaaacacagaaaaataagcaa
agaaatgaagtggacggcagcaatgaaaaagcagcccttctcccagccccctttgcacta
ggagatacaaacgttaccatagaagagcaattaaactcaataaatttatcttttcaggat
gatccagactccagtaccagtacattaggaaacatgctagaattacctggaacttcatca
tcatctacttcacaggaattgccattttgtcaacccaagaaaaagtctacgccactgaag
tatgaagttggagatctcatctgggcaaaattcaagagacgcccatggtggccctgcagg
atttgttctgatccgttgattaatacacattcaaaaatgaaagtttcaaaccggaggccc
tatcgacaatactatgtggaggcttttggggacccttcagagagagcctgggtggctgga
aaagcaatcgtcatgttcgaaggcagacatcaatttgaagagctacctgttcttaggaga
agagggaagcagaaagaaaaaggatataggcacaaggttcctcagaaaattttgagtaaa
tgggaagccagtgttggtcttgctgaacagtatgatgttcccaaagggtcgaagaaccga
agatgtgtcagcagttcaatcaagttggacagtgaggaggatatgccatttgaggattgt
acaaatgatcctgaatcagaacatgacctattacttaatggctgcttgaaatctctggct
tttgactctgaacattctgcagatgaaaaggaaaagccttgtgctaagtctcgagccaga
aagagttctgataatccaaaaaggactagtatgaaaaagggccacatgcaatttgaagca
cataaggaagaacgaaggggaaagattccagagaaccttggcctaagctttatttctggg
gatgtatctgataagcaggcctctaatgaactttccaggatagcaaatagcctcacaggg
tccaacactgccccaggaagtttcctattttcttcttgtggaaaaaacacagcaaagaag
gaatttgagacttcaaattgtgactctttactgggcttgtctgagggtgccttgatctct
aaacattctgaggaaaagaagaaactccaacgaggtttgatgtgtagttcaaaagtacag
ctctgttatattggagcaggtgatgaagaaaagcgaagtgattccattagtatctgtacc
acctctgatgatggaagcagtgatctggatcccatagataatagttcagagtctgataac
agtgtccttgaaattacagatgcttttgatagaacagagaacatgttatctgttcagaaa
aatgaaaaggtaaagtatactaggtatcctgccacaaacactaaggtaaaagcaaagcag
aagtccctcattactaactcacatacagaccacttaatggattgtgctaagacagtagag
cctggaactgaaacatctcaggttaatctctctgatcttaaagtatctgctgttgttcgc
aaaccccagtcagattttagaaatgatagtttctctccaaaattcaacacaccatcaagc
atttccagtgagaactcactaataaaaagtggggctacaaatcaagctctgttacatgca
aaaagcaaacagcccaagatccgaagtataaagtgcaaacataaagaaaatcccgttgta
gtggaacctccagttacaaatgaggactgcagtttgaaatgctgctcttctgataccaaa
ggctctcctttggccagcatatccaaaagtgggaaagtggatgggctaaaactactgagc
aacatgcatgagaaaaccagggattcaaatgacatagaaacagcagtggtgaaacatgtt
ctgtcagagttgaaggaactctcttatagatccttaagtgaagatgtgagtgactcggga
acatcaaagccgtcaaaaccattacttttttcttctgcctctggtcagaatcatatacct
attgaaccagactataaattcagtacattgctaatgatgttgaaagatatgcatgatagt
aagaccaaggagcaacggttaatgactgctcaaaatttggtctcgtatcggagtcctggt
cttggagactgttcttcgagtagtcctgtaagtgcatctaaggtcttggtttcaggcagc
tccactcacagttcagaaaaaaatggagatggcactcagaaatcagtccgtcctagccct
agtgggggtgactctgcactgtctggagaattatctgtacctgtacctggcttagtgtct
gacagaagagatgtccctgcttctagtaaaagtcattcagactgtgttactaggcgcaac
tgtgggcgttcaaaaccatcatctaaattgcgagatagttttgcagcccagatgggaagg
aacacattgaaccgtaaagccttaaagacagagcgcaaaagaaaactcagccgacttcca
gctgtgactcttgaggctgccctgcagggagacagagtaagtggagattcagagaatggt
tcctcaagaggtgggctagaagactctggtaaagaagaaccccttcagttaatgggccat
ttaacaagtgaagacagtgcccatttttccagtgttcattttgataacaaagtcaaccac
cctgaccctgataaaattccagagaaaggtccctcttttgaaaacagaaaaggcccagag
ttggataatgaaatgaacagtgagaatgatgaacccagtggtgtaaatcaagctgtgcct
aaaaagcggtggcagcgtttaaaccaaaggcgcaccaaacctcgtaagcgcactaacaga
tttagggagaaagaaaactctgagggtgcctttggggttttgcttccatctgaccctgta
aagaagggggatgagttcccagagcatagaccccctacttcaacaaatgtaatagaagat
acactggctgatccaaatcataccagctgcttagattcaattggaccacggttgaatgtt
tgtgataaatccagtgccagcgttgaagagatggaaaaagagccgggaattcccagtttg
acaccccaacctgagctccctgaaccagctgtgcggtcagagaagaaacgccttaggaag
ccaagcaagtggcttctggaatatacagaagaatatgatcagatatttgctcctaagaaa
aaacaaaagaaggtacaggaacaggtgcacaaggtaagttcccgctgtgaagaggaaagc
cttttagcccgatgtcgatctagtgctcagaacaagcaggtggatgagaattctttgatt
tcaaccaaagaagagcctccagttcttgaaagggaggctccatttttggaagggcccttg
gctcagtcagaacttggaggtggacatgctgagttaccacagctgaccttgtctgtgcct
gtggctcccgaagtgtctccacggcctatccttgagtctgaggagttactagttaaaaca
ccaggaaattatgaaagtaaacgtcaaagaaaaccaactaagaaacttcttgaatccaat
gatttagacccgggatttatgcccaagaaaggggatcttggtctttctaaaaagtgttat
gaagctggtcatttggagaatgacagtgaatcacgtgctgcatctagggagtacggtgga
ggtgctgccaagatatttgataaaccaagaaaacgaaaacgacagaggcatgctacagcc
aaggtgcattgtaaaaaaatgaaaaatgacgactcttcaaaagaaactccaggctcagag
ggagaactgatgacacaccgaacggctgcaagccccaaggagactgttgaggagagtgta
gagaacgatcatgggatgccggcatctaaaaagctgcagggtgaacgaggcggaggagct
gcactcaaggagaatgtttgtcagaactgtgagaaactgggtgagctgctgttatgtgag
gctcagtgctgtggggctttccacctggagtgccttggattaactgaaatgccaagagga
aaatttatctgcaatgaatgtcgcacaggaatccatacctgttttgtttgtaagcagagt
ggggaagatgttaaaaggtgccttttgcccttgtgtggaaagttttatcatgaagagtgt
gtccagaagtatccacccactgtcatgcagaacaagggcttccggtgctccctccacatc
tgtataacctgccatgctgctaatccagccagtgtttctgcatctaaaggtcgcctgatg
cgctgtgtccgctgccctgtggcataccatgccaatgacttttgcctggctgccgggtcc
aagattcttgcatctaatagtatcatctgccctaatcactttacacctaggcggggctgc
cgaaaccatgagcatgttaatgttagctggtgttttgtatgctcagaaggaggcagcctt
ctatgctgtgattcctgccctgcagcttttcatcgtgaatgcctgaacattgatatccct
gaaggaaactggtattgcaatgattgtaaggcaggcaaaaagccgcattacagggaaatt
gtttgggtaaaagttgggcgatacaggtggtggccagctgagatctgccatcctcgagct
gtaccttccaatattgataagatgagacatgatgtgggcgagttccctgtgcttttcttt
ggatctaatgactatctgtggacgcatcaggcccgagtctttccctatatggagggggat
gtgagcagcaaggataagatgggcaaaggagtagatgggacatataaaaaagctcttcag
gaagctgcagcaaggtttgaggagttaaaggcccaaaaagagctaagacagctgcaggaa
gaccgaaagaatgacaagaaacctccgccttacaaacatataaaggtgaaccgtcctatt
ggcagggtacagatcttcactgcagacttgtctgaaattccccgttgcaactgtaaagct
actgatgataatccttgtgggatagactctgagtgcatcaatcgcatgctactatatgag
tgccaccccacagtatgtcctgctggaggacgctgccaaaaccagtgtttcactaagcgc
cagtatccagaggttgaaattttccgcacgttacagaggggttggggtcttcggactaaa
acagatattaaaaagggtgaatttgtgaatgagtatgtgggtgagctaatagatgaagaa
gagtgcagagctcgaatccgttatgcccaggaacatgatatcactaatttctatatgctt
accctagacaaagaccggatcattgatgctggtcccaaaggaaactatgctcggtttatg
aatcattgctgccagcccaactgtgaaacacagaaatggtctgtgaatggagatacccgt
gttggcctttttgccctgagtgacattaaagcaggcactgaacttaccttcaactacaac
ctagaatgtcttgggaatggaaagactgtttgcaagtgtggagccccaaactgcagcggg
tttttgggtgtaaggccaaagaatcagccgattgccacagaagaaaagtcaaagaaattc
aagaagaagcaacaggggaagcgcaggacccagggtgaaatcacaaaggagagagaggat
gagtgtttcagctgtggggatgctggccagctcgtctcctgtaagaagccaggctgccca
aaagtttaccacgctgactgtctaaatctaaccaagcgaccagcagggaaatgggagtgt
ccttggcatcagtgtgacatctgtgggaaggaagcagcctccttctgtgagatgtgtccc
agctccttttgtaaacagcatcgggaagggatgctcttcatctccaaactggatgggcgt
ttgtcttgtactgagcatgacccctgtgggcccaaccctttggaacctggggagatccgt
gagtatgtgcctcccccagtaccgctgcctccaggcccaggcactcacctggcagagcat
tcatcaggagtggctgctcaggggcccaagatgttggataagctgcctgctgacaccaac
cagacactgtcactgtccaaaaaagctctggcaggaacttgtcagaggccactgctgcct
gaaagacctcctgatagaactgactccaggccccagcctgtagatagggtcagggacctt
gctgggtcggggaccaaaccccaatccttggtatccagccagaagccattggacaggcca
cctgcagtggcaggaccaagacccctactatctgacaaaccctctccagtgaccggtata
agctcctcaccctcagtcaggtctcaatcactggaaagacctctggggacagctgaccca
aggctggataaatccataggtgctgccagcccaaggccccagtcactggagaaaacccca
ggccctcctggcctgagacttccaccgccagacagactgcttgtcaccagcagtcccaaa
ccccagacttcagacaggcccccagacaaatcccatgcttctttgtcccagagactccca
cctcctgacaaagtactttcagctgtggtccagaccctggtagctaaagaaaaagcactg
aggcccgtggaccagaatactcagtcaaaaaatagagctgctttggtgatggatctcata
gacctaactcctcaccagaaagagcgggctgcttcacctcatgaggtcacaccacaggtt
gatgagaagatgccagtgttggagtcaagctcatggactgccagtaaaggtctggggcag
atgccacgagctgtagagagaggcagtatgtcagaccctgtccttcagccaccagggaaa
acagccgtcccttcggagcacccctggcaagcggttaaatcactcacccaggccagactt
ctctctcagccttctgccaaggcttttttatatgagccaacaactcaggcctcaggaaga
gcacctgcaggggtggagcagataccagggcctcccagccaagcaccaggcctggtgaag
caggtgaagcagatgaccggaggccagcaactacctggacttgctgccaagagtgggcag
tccttcaggcctcttgggaaggccccatccaccctctgtactgaagagaagaagttggca
actgcagagcagagtccctgggccctgggaaagtcctcaccagggccagggctctggccc
atggtggctggacagacaatatcgccgtcttgctggtcctctgggaacacacagacattg
gcacagacttgctggtctcttggaagagggcaagaccctaaaccagagcaaaatacactt
ccagctcttaaccaggctccttccagtcacaagtgtgcagagtcagaacagaagtaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (47)   
   KEGG ORTHOLOGY (1)   
   RefGene (41)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (42)   
   UniProt (2)   
   RefSeq(pep) (40)   
DNA sequence (40)   
   RefSeq(nuc) (40)   
Protein domain (7)   
   Pfam (7)   
All databases (152)   

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