KEGG   Canis lupus familiaris (dog): 489188
Entry
489188            CDS       T01007                                 
Symbol
CSF1R
Name
(RefSeq) macrophage colony-stimulating factor 1 receptor
  KO
K05090  macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04010  MAPK signaling pathway
cfa04014  Ras signaling pathway
cfa04015  Rap1 signaling pathway
cfa04060  Cytokine-cytokine receptor interaction
cfa04061  Viral protein interaction with cytokine and cytokine receptor
cfa04151  PI3K-Akt signaling pathway
cfa04380  Osteoclast differentiation
cfa04640  Hematopoietic cell lineage
cfa05200  Pathways in cancer
cfa05202  Transcriptional misregulation in cancer
cfa05221  Acute myeloid leukemia
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    489188 (CSF1R)
   04014 Ras signaling pathway
    489188 (CSF1R)
   04015 Rap1 signaling pathway
    489188 (CSF1R)
   04151 PI3K-Akt signaling pathway
    489188 (CSF1R)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    489188 (CSF1R)
   04061 Viral protein interaction with cytokine and cytokine receptor
    489188 (CSF1R)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    489188 (CSF1R)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    489188 (CSF1R)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    489188 (CSF1R)
   05202 Transcriptional misregulation in cancer
    489188 (CSF1R)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    489188 (CSF1R)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cfa01001]
    489188 (CSF1R)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:cfa04090]
    489188 (CSF1R)
Enzymes [BR:cfa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     489188 (CSF1R)
Protein kinases [BR:cfa01001]
 Receptor tyrosine kinases (RTK)
  PDGFR family [OT]
   489188 (CSF1R)
CD molecules [BR:cfa04090]
 Proteins
  489188 (CSF1R)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase Ig_3 ig I-set Ig_2 V-set VEGFR-1-like_Ig-like V-set_CD47
Other DBs
NCBI-GeneID: 489188
NCBI-ProteinID: XP_546306
Ensembl: ENSCAFG00000018219
VGNC: 39653
UniProt: A0A8C0S771
Position
4:58746695..58776657
AA seq 967 aa
MGLGAPLVLLVATAWHVRGVPVIEPRGPELVVEPGTAVTLRCVGNGSVEWEGPISPHWNL
DPDSPSSILSTNNATFLNTGTYRCTEPGSPLGGSATIHIYVKDPVRPWKVLTQEVTVLEG
QDALLPCLLTDPALEAGVSLMRVRGRPVLRQTNYSFSPWYGFTIHKAQFTETQGYQCSAR
VGGRTVTSMGIWLKVQKVIPGPPTLTLKPAELVRIQGEAANIECSASNVDVNFDVFLQHE
DTKLTIPQQSDFQGNQYQKVLTLELDHVGFQDAGNYTCVATNVRGISSTSMIFRVVESAY
LNLTSEQSLLQEVTVGEKVDLQVKVEAYPSLEGYNWTYLGPFSDQQAKLKFVITKDTYRY
TSTLSLPRLKPSEAGRYSFLARNTRGGDSLTFELTLLYPPEVRITWTTVNGSDALLCEAS
GYPQPNVTWLQCRGHTDRCDEAQALVLEDSYSEVLSQEPFHKVIVHSLLAMGTMEHNMTY
ECRALNSVGNSSQAFRPIPIGAHIQPPDEPLFTPVLVTCMSIMVLLLLLLLLLFYKYKQK
PKYQVRWKIIESYEGNSYTFIDPTQLPYNEKWEFPRNNLQFGKTLGAGAFGKVVEATAFG
LGKEDAVLKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTHGGPVLVIT
EYCCYGDLLNFLRRKAEAMLGPSVSVGQDPGAGAGYKNIHLEKKYVRRDSGFSSQGVDTY
VEMRPVSTSSSNDSFSEQDLDKEDGRPLELRDLLHFSSQVAQGMAFLASKNCIHRDVAAR
NVLLTSGRVAKIGDFGLARDIMNDSNYIVKGNARLPVKWMAPESIFDCVYTVQSDVWSYG
ILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSVMQACWALEPTRRPT
FQQICSLLQEQAQADRREPDYTNLPSSSSSSGSSSEPEEESSSEHLACCEQGDIAQPLLQ
PNNYQFC
NT seq 2904 nt   +upstreamnt  +downstreamnt
atgggcctaggggctccactggttctgctggtggccacagcttggcatgttcgaggagtc
ccagtgatagaacccagaggcccagagctggtcgtggagccaggcacagcagtgaccctg
cgatgtgtgggcaacggcagcgtggaatgggaaggccccatctccccacactggaacctg
gaccctgattcccccagcagcatcctgagcacgaataatgccaccttcctgaacaccggg
acctatcgctgcactgagcctggaagccccctggggggcagtgccaccatccacatctat
gtcaaagaccctgttcggccttggaaggtgctgacccaggaagtgacggtgttggagggg
caggatgcgctgctgccctgcctgcttaccgacccagcgttggaggcaggcgtctcgctg
atgcgggtgcgtggccggcctgtcttgcgccaaaccaactattccttctcgccctggtat
ggcttcaccatccacaaggcccagttcaccgagacccagggctaccaatgcagcgctcga
gtaggcggcaggacggtaacgtcgatgggcatctggcttaaagtgcagaaagtcatccca
gggcccccgaccttgacgctgaagcctgcagagctggtacggattcagggagaggccgcc
aacatcgagtgctcggccagcaatgttgatgttaactttgacgtcttcctgcaacacgaa
gacaccaagctcacaatccctcaacaatctgacttccaaggtaaccagtaccaaaaagtc
ctgaccctcgagctcgatcacgtaggcttccaagatgctggcaactacacctgcgtggcc
accaatgttcgaggcatcagctccacctccatgatcttccgggtggtagagagtgcctac
ttgaacttgacctctgagcagagcctcctccaggaagtgactgtgggtgagaaggtcgat
ctccaagtcaaggtggaggcctacccaagcctggaaggttataactggacctatctggga
cctttctccgaccagcaggccaaactcaagtttgtcatcacgaaggacacatacaggtat
acctccaccctctccctgcctcgcttgaagccttcagaggccggtcgctattccttcctg
gccagaaacactagaggcggggattctctgacctttgagctcaccctactatacccccca
gaggtcaggatcacatggaccactgtcaacggctctgacgcactgctctgtgaagcctct
gggtatccccagcccaatgtgacatggctgcagtgcagaggccacacagatagatgtgat
gaggcccaagcgctggtcctagaggactcctactcggaggtcctgagccaggagcccttc
cacaaggtgatcgtccacagcctgctggccatggggaccatggaacacaacatgacttat
gagtgcagggccctcaacagcgtggggaacagctcccaggccttcaggcccatccccata
ggagcccacatccagcctcctgacgagccgctcttcacgcctgtgttggtcacctgcatg
tccatcatggtcttgctgcttttgctgctcttgctgcttttctacaaatataagcagaag
cccaagtaccaggtgcgctggaagatcatcgagagctacgagggcaacagctacacgttc
attgaccccacccagctgccctacaatgagaagtgggagtttccacgaaacaacctgcag
tttgggaagactctcggagccggtgcctttgggaaggtggtagaggccacagcctttggt
ttgggcaaggaggatgctgtcctgaaggtggctgtgaagatgctgaagtccacagctcac
gcagacgagaaggaggccctcatgtcggaactgaagatcatgagtcacctgggccagcac
gagaacatagtcaaccttctgggagcctgtacccatggaggcccggttctggtcatcacc
gagtactgttgctatggtgacctgctcaactttctgcgaaggaaggctgaggccatgctg
ggacccagtgtgagtgtgggccaggaccccggggcaggtgctggctacaagaacatccac
ctggagaagaaatatgtccgcagggacagcggcttctccagccagggtgtagacacctac
gtggaaatgaggcctgtctctacttcttcgtcaaacgactccttttctgaacaagacctg
gacaaagaggatgggcgaccactagagctgcgggacctgctccatttctcgagccaggtg
gctcagggcatggccttccttgcatccaagaactgcatccaccgggacgtggcagcccga
aacgtcttgctgaccagtgggcgtgtggccaagattggggactttgggctggccagggac
atcatgaatgactccaactacatcgtcaaaggcaatgcccgcctgcccgtgaagtggatg
gctccagagagcatctttgactgtgtctacacggttcagagtgacgtctggtcctacggc
atcctgctctgggaaatcttctcactcgggctgaacccctaccctggcatcctggtgaac
agcaagttctataaactagtgaaggatggataccaaatggcccagcctgcattcgccccc
aagaacatatacagcgtcatgcaggcctgctgggccctggagcccacccgaagacccacc
ttccagcagatctgctccctcctccaggagcaggcccaagcagacaggagagagccagac
tacaccaatctgccaagcagcagcagtagcagtggcagcagtagtgagccagaggaggag
agctctagcgagcacctggcctgctgtgaacagggggatattgcccagcccctgctgcag
cccaacaactaccagttctgctga

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (11)   
   KEGG PATHWAY (11)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (6)   
   UniProt (1)   
   RefSeq(pep) (5)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (9)   
   Pfam (9)   
All databases (56)   

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