KEGG   Canis lupus familiaris (dog): 491845
Entry
491845            CDS       T01007                                 
Symbol
KDM6A
Name
(RefSeq) lysine-specific demethylase 6A isoform 1
  KO
K11447  lysine-specific demethylase 6A [EC:1.14.11.68]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa05202  Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    491845 (KDM6A)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:cfa03036]
    491845 (KDM6A)
Enzymes [BR:cfa01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.68  [histone H3]-trimethyl-L-lysine27 demethylase
     491845 (KDM6A)
Chromosome and associated proteins [BR:cfa03036]
 Eukaryotic type
  Histone modification proteins
   HMT complexes
    MLL3/MLL4 complex
     491845 (KDM6A)
   Histone demethylases
    491845 (KDM6A)
SSDB
Motif
Pfam: KDM6_C-hel JmjC KDM6_GATAL TPR_1 TPR_2 TPR_8 TPR_16 TPR_17 TPR_12 TPR_19 TPR_7 TPR_9 TPR_11 SNAP TPR_15 ANAPC3
Other DBs
NCBI-GeneID: 491845
NCBI-ProteinID: NP_001184114
Ensembl: ENSCAFG00000014589
VGNC: 54168
UniProt: A0A8C0YYX1 A0A8I3Q6F2 E1NZ77 E1NZ78
Position
X:25972576..26186531
AA seq 1419 aa
MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
SLQSDYWKNAAFLYGLGLVYFHYNAFHWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE
EAWSLPIPAELTSRQGAMNTAQQACKPHHPNTEPVLGLSQTPISQQSLPLHMIPSSQVDD
LSSPAKRKRTSSPTKNTSDNWSSGHAVSHPPVQQQAHSWCLTPQKLQMRQTGVAQVRSTG
IPNGPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTS
RTLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQG
LHKGQSSHLAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSH
TATSGGQQGITLTKESKPSGNTSMVPETSRHAGETPNSTASVEGLPNHVHQVTADAVCSP
SHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSA
ISTATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKTDVLLISHKPNPQII
PSMSVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPS
IYLENKRDAFFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRT
QLLQPADENWDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSD
SESTSSDNSGRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHV
GHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCE
KNNLNFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVG
PLTACQYKLAVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQ
CQTLREALIAAGKEIIWHGRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCA
RKTSGNLENFVVLEQYKMEDLMQVYDQFTLAPPLPSSSS
NT seq 4260 nt   +upstreamnt  +downstreamnt
atgaaatcctgcggagtgtcgctcgctaccgccgccgctgccgccgccgctttcggtgat
gaggaaaagaaaatggcggcgggaaaagcgagcggcgagagcgaggaggcgtcccccagc
ctgacagccgaggagagggaggcgctcggcggactggacagccgcctattcgggttcgtg
aggtttcatgaagatggcgccaggacgaaggccctactgggcaaggctgttcgctgctac
gaatctctaatcttaaaagctgaaggaaaagtggagtctgatttcttttgtcaattaggt
cacttcaacctcttattggaagattatccaaaagcattatctgcataccagaggtactac
agtttacaatctgactactggaagaatgctgcctttttatatggtcttggtttggtctac
ttccattacaatgcatttcactgggcaattaaagcatttcaggaggtgctttatgttgat
cccagcttttgtcgagccaaggaaattcatttacgacttgggcttatgttcaaagtgaat
acagactatgagtctagtttaaagcattttcagttagctttggttgactgcaatccatgc
actttgtccaatgctgaaattcaatttcacattgcccacttatatgaaacccagaggaag
tatcattctgcaaaggaagcttatgaacaacttttgcagacggaaaacctttctgcacaa
gtaaaggcaactgtcttacaacagttaggttggatgcatcacactgtagatcttctggga
gataaagctaccaaggaaagctatgctattcagtatctccaaaagtccttggaagcagat
cctaattctggccagtcctggtatttccttggaaggtgctattcaagtattgggaaagtt
caggatgcctttatatcttacaggcagtctattgataaatcagaagcaagtgcagataca
tggtgttcaataggcgtgctatatcagcagcaaaatcagcctatggatgctttacaggct
tatatttgtgctgtacaattggaccatggccatgctgcagcctggatggacctaggcaca
ctctacgaatcctgcaaccagcctcaggatgccattaaatgctacttaaatgcaaccaga
agcaaaagttgtagtaatacctctgcacttgcagcacgaattaagtatttacaggctcag
ttgtgtaaccttccacaaggtagtctacagaataaaactaaattacttcctagtattgag
gaggcgtggagcctaccaatccccgcagagcttacctccaggcagggtgccatgaacaca
gcacagcaggcatgtaaacctcatcatccaaatactgaacctgtattaggcctcagtcaa
acaccaatttcacagcagtccttgccactacacatgattccttctagccaagtagatgac
ctgtccagtcctgccaagaggaaaagaacatctagtccaacaaagaatacttctgataat
tggagtagtggccatgcagtgtcacatcctccagtacagcaacaagctcattcgtggtgt
ttgacaccacagaaattacagatgagacaaacaggagttgcacaggtacgatctactgga
attcctaatgggccaacagctgactcatcactgcctacaaactcagtctctggccagcag
ccacagcttgctctgaccagagtgcctagcgtctctcagcctggagtccgccctgcctgc
cctgggcagcctttggccaacggacccttttctgcaggccatgttccctgtagcacatca
agaacgctggggagtacagacactatattgataggcaataatcacataacaggaagtgga
agtaatggaaacgtgccttacctgcagcgaaacgcactcactctacctcataaccgcaca
aacctgaccagcagcgcagaggagccgtggaaaaaccaactatctaactccactcagggg
cttcacaaaggtcagagttcacatttggcaggtcctaatggtgaacgacctctctcttcc
actgggccttcccagcatctccaggcagctggctctggtattcagaatcagaatggacat
cccaccctgcctagcaattcagtaacacagggggctgctctcaatcacctctcctctcac
actgctacctcaggtggacaacaaggcattaccttaaccaaagagagcaagccttcagga
aacacatcgatggtgcctgaaacaagcaggcacgctggagagacacctaacagcactgcc
agtgtcgagggacttcctaatcatgtccatcaggtgacggcagatgctgtttgcagtcct
agccatggagattctaagtcaccaggtttactaagttcagacaatcctcagctctctgcc
ttgttgatgggaaaagccaataacaatgtgggtactggaacctgtgacaaagtcaataac
atccacccagctgttcatacaaagactgataattctgttgcctcttcaccatcttcagcc
atttccacagcaacaccttctccaaaatccactgagcagacaaccacaaacagtgttacc
agccttaatagccctcacagtgggctacacacaattaatggagaaggaatggaggaatct
cagagccccatgaaaacagatgtgcttctgattagccacaaacctaatcctcagatcata
ccatcaatgtctgtatccatataccccagctcagcagaagttctgaaggcatgcaggaat
ctaggtaaaaatggcttatctaacagtagcattttattggataaatgtccgcctccaaga
ccaccatcttcaccataccctcccttgccaaaggacaagttgaatccacctacacctagt
atttatttggaaaataaacgtgatgctttctttcctccattacaccaattttgtacaaat
ccaaacaaccctgttacggtaatacgtggccttgctggagctcttaagttggacctggga
cttttctctaccaaaactttggtggaagctaacaatgaacatatggtggaagtgaggaca
cagttgttgcaaccagcagatgaaaactgggatcctactggaacaaagaaaatctggcat
tgtgaaagtaatcgatctcatactacaattgctaaatatgcacagtaccaggcctcctcc
ttccaggaatcattgagggaagaaaatgagaaaagaagtcaccataaagaccattcagat
agtgaatctacatcttcagataattctgggaggaggaggaaaggaccctttaaaaccata
aagtttgggaccaacattgacctgtctgatgacaaaaaatggaagttgcagctacatgag
ctgactaaacttcctgcttttgtgcgtgtcgtatcagcaggaaatcttctaagccacgtt
ggtcataccatactgggcatgaacacagttcaactgtacatgaaagttccaggaagcaga
acaccaggtcatcaagaaaataacaacttctgttcggttaatataaatattggtccaggt
gactgtgaatggtttgttgtccctgaaggttactggggtgttctgaatgacttctgtgaa
aaaaataatttgaatttcctaatgggttcttggtggcccaaccttgaagatctttatgaa
gcaaatgttccagtgtataggtttattcagcgacctggagatttggtctggataaatgca
ggcactgttcattgggttcaggctattggctggtgcaacaacattgcttggaatgttggt
ccacttacagcctgccagtataaattggcagtggaacggtacgaatggaacaaattgcaa
agtgtgaagtcaatagtacccatggttcatctttcctggaatatggcacgaaatatcaag
gtctcagatccaaagctttttgaaatgattaagtattgtcttctgagaactctgaagcaa
tgtcagacattgagggaagctctcattgctgcaggaaaagagattatatggcatgggcgg
acaaaagaagaaccagcgcattactgtagcatttgtgaggtggaggtttttgatctgctt
tttgtcacaaatgagagcaattctcgaaagacctacatagtgcattgccaagactgtgca
cgaaaaacaagtggaaacctggaaaattttgtggtgctagaacagtataaaatggaggac
ctgatgcaagtctatgaccaatttacattagctcctccattaccatcctcctcatcttga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (11)   
   UniProt (4)   
   RefSeq(pep) (7)   
DNA sequence (14)   
   RefSeq(nuc) (8)   
   GenBank (3)   
   EMBL (3)   
Protein domain (16)   
   Pfam (16)   
All databases (66)   

Download RDF
DBGET integrated database retrieval system