KEGG   Canis lupus familiaris (dog): 494000
Entry
494000            CDS       T01007                                 
Symbol
VHL
Name
(RefSeq) von Hippel-Lindau disease tumor suppressor
  KO
K03871  von Hippel-Lindau disease tumor supressor
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04066  HIF-1 signaling pathway
cfa04120  Ubiquitin mediated proteolysis
cfa05200  Pathways in cancer
cfa05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    494000 (VHL)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    494000 (VHL)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    494000 (VHL)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    494000 (VHL)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:cfa04121]
    494000 (VHL)
Ubiquitin system [BR:cfa04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   Cul2 complex
    Target recognizing subunit
     494000 (VHL)
SSDB
Motif
Pfam: VHL VHL_C Arm_vescicular
Other DBs
NCBI-GeneID: 494000
NCBI-ProteinID: NP_001008552
Ensembl: ENSCAFG00000044690
UniProt: Q5Q9Z2
Position
20:complement(8240602..8245270)
AA seq 219 aa
MPRKAGSVEEAEAGAEEVGAEEVGPEESGGEESGAEESGPEESDPEEPGAAAEMEAGQPR
PVLRSVNSCEPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRIHSYRGHLWLFR
DAGTYDGLLVNQTELFVPSLNVDGQPIFANITLPVYTLKERCLQVVRSLVKPENYRRLDI
VRSLYEDLEDHPNVRKDLERLAQEHIENQRMEGETEDFN
NT seq 660 nt   +upstreamnt  +downstreamnt
atgccccggaaggcagggagcgtggaggaggccgaggcgggcgccgaggaggtgggcgcc
gaggaggtgggccctgaagagtccggcggggaggagtctggcgcggaggagtccggcccg
gaagagtctgacccggaggagccgggcgctgcggcggagatggaggccgggcagccgcgg
ccggtgctgcgctcggtgaactcgtgcgagccgtcccaggtcatcttctgcaaccgcagc
ccgcgcgtcgtgctgccggtgtggctcaacttcgacggcgagccgcagccctacccgacg
ctgccgccgggcacgggccgccgcatccacagctaccgaggtcacctttggctcttccga
gatgccgggacatatgatgggcttctggttaaccaaactgaactatttgtgccatctctc
aatgttgatggacagccaatttttgccaacatcacactgccagtgtatactctgaaagag
cggtgcctccaggttgtccgaagcctagtcaagcctgagaattataggagactggacatc
gtgagatccctctatgaagatctggaagaccacccgaatgtaaggaaagacctggagcgg
ctggcacaggagcatattgaaaatcagcgaatggaaggggagactgaggattttaattga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
Protein domain (3)   
   Pfam (3)   
All databases (27)   

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