KEGG   Canis lupus familiaris (dog): 494002
Entry
494002            CDS       T01007                                 
Symbol
MSH2
Name
(RefSeq) DNA mismatch repair protein Msh2
  KO
K08735  DNA mismatch repair protein MSH2
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa01524  Platinum drug resistance
cfa03430  Mismatch repair
cfa05200  Pathways in cancer
cfa05210  Colorectal cancer
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03430 Mismatch repair
    494002 (MSH2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    494002 (MSH2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    494002 (MSH2)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    494002 (MSH2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:cfa03400]
    494002 (MSH2)
DNA repair and recombination proteins [BR:cfa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   MMR (mismatch excision repair)
    Mismatch and loop recognition factors
     494002 (MSH2)
SSDB
Motif
Pfam: MutS_V MutS_III MutS_II MutS_IV MutS_I AAA_27 FeoA
Other DBs
NCBI-GeneID: 494002
NCBI-ProteinID: XP_538482
Ensembl: ENSCAFG00000002659
VGNC: 43438
UniProt: A0A8C0SBJ9 A0A8I3MVG3
Position
10:49372675..49449176
AA seq 934 aa
MAVQPKETLQLESAAEVGFVRFFQAMPEKPTTTVRLFDRGDFYTAHHEDALLAAREVFKT
QGVIKYLGPAGTKTLESVVLSKMNFESFVKDLLLIRQYRVEVYKNRAGSKASKENDWYLA
FKASPGNLSQFEDILFGNNDMSTSIGVVGVKMSTVDGQRQVGVGYVDSIQRKLGLCEFPD
NDQFSNLEALLIQIGPKECVLPGGETAGDMGKLRQVIQRGGILITERKRADFFTKDIYQD
LNRLLKGKKGEQVNSAVLPEMENQVAASALSAVIKFLELLSDDSNFGQYELTTFDFSQYM
KLDIAAVRALNLFQGSVEDTTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERL
NLVEAFVEDAELRQSLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIRA
LEKYEGKHQGLLLAVFVTPLIDLRSDFSKFQEMIETTLDMDQVENHEFLVKPSFDPNLSE
LREIMDDLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFS
TVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLA
QLDAVVSFAHVSNGAPVPYVRPVILEKGQGRITLKASRHACVEVQDEVAFIPNDVHFEKD
KQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLK
GVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMF
ATHFHELTALANQIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANFPRHV
IECAKQKALELEEFQNIGGSQGYDEMEPAAKRCYLEREQGEKIIQEFLSKVKQVPFTEMS
EENITMKLKQLKAEVIAKNNSFVNEIISRIKVST
NT seq 2805 nt   +upstreamnt  +downstreamnt
atggcggtgcagcccaaggagacgctgcagctggagagcgcggccgaggtcggcttcgtg
cgcttcttccaggccatgccggagaagccgaccaccacggtgcgcctcttcgaccggggc
gacttctacacggcgcaccacgaggacgcgctgctggccgcccgagaggtgttcaagacg
cagggggtaatcaagtacctcgggccggcaggaacaaagaccctggagagtgttgtgctt
agtaaaatgaattttgaatcttttgttaaagatcttcttctaattcgacagtatagagtt
gaagtttacaagaatagagctggaagtaaggcctccaaggagaacgattggtatttggca
tttaaggcttctccaggtaatctttctcagtttgaagacattctctttggtaacaatgat
atgtcaacctccattggtgtcgtgggtgttaaaatgtctacagttgatggccaaagacag
gtcggagttgggtatgttgactccatacagaggaagctaggactttgtgagttccctgat
aatgatcagttctccaatttggaggctctcctgattcagattggaccaaaggaatgtgtt
ttaccaggaggagagactgctggagacatgggaaaactgaggcaggttattcagagagga
ggaattctgatcacagaacgaaaaagagctgatttttttacaaaagatatttatcaggac
ttgaaccggttattgaaaggcaaaaagggagaacaggtgaatagtgctgtcttgccagaa
atggagaatcaggttgcagcttcagcactgtctgcagtaatcaagtttttagaactttta
tcagatgattcaaactttggacagtatgaactcactacttttgacttcagccagtatatg
aagttggatattgcagcagtccgagcccttaaccttttccagggttctgttgaagatact
actggctctcagtctctggctgcattgctgaataaatgcaaaacccctcagggacaaaga
ctggttaaccagtggattaagcagcctctcatggataagaacagaatagaagagagactg
aatttagtggaagcttttgtagaagatgcagaattgaggcagagtttacaagaagattta
cttcgtcgattcccagatcttaaccgacttgccaagaaatttcagagacaagcagcaaac
ttacaagattgttaccgactctatcagggtataaatcaactccctaatgttattcgggct
ctggagaaatatgaaggaaaacaccaaggtttattgttggcagtttttgtcactcctctt
attgatcttcgttctgatttctccaaatttcaggaaatgattgaaacaactctagatatg
gatcaggtggaaaaccatgaattccttgtaaaaccttcatttgatcccaatctgagtgaa
ttaagggaaataatggatgacttagaaaagaagatgcagtcaacattgataagtgcagca
agagatctaggtttggatcctggcaaacagattaaactggattccagtgcacagtttggt
tattattttcgagtaacatgtaaggaagaaaaagtccttcgcaacaataaaaacttcagt
acagtagatatccagaagaatggtgttaaatttaccaacagcaaactgacttctctcaat
gaagagtataccaaaaataaaaccgagtacgaggaagcccaggatgccattgttaaagaa
attgtcaatatttcttcaggctatgtcgaaccaatgcagacactcaatgatgtgttagct
cagctagacgctgttgtcagcttcgctcatgtgtcaaatggagcacctgttccatatgta
cgaccggtcattttggaaaaaggacaaggaagaattacattgaaagcatccagacatgct
tgtgttgaagttcaagatgaagttgcatttattcctaatgatgttcactttgaaaaagat
aaacagatgttccacatcattactggccccaatatgggaggtaaatcaacatatattcgc
caaactggggtgatagttctcatggcccagattgggtgttttgtgccgtgtgagtcagca
gaagtgtccattgtggactgcatcttggcccgtgtaggggctggtgacagtcagttgaaa
ggagtctccacatttatggctgaaatgctagagactgcttctattctcaggtctgcaacc
aaagattctttaataatcatagatgaattgggaagaggaacctctacctatgatggattt
ggattagcgtgggctatatcagagtacattgcaacaaagattggtgctttttgcatgttt
gcaacacattttcatgaacttactgccttggccaatcagataccaactgttaataatcta
catgtcacagcactaactactgaagagaccttaactatgctttatcaggtgaagaaaggt
gtctgtgatcaaagtttcgggattcatgttgcagagcttgcaaatttccctagacatgtt
atagagtgtgctaaacaaaaagccctggaactagaggagtttcagaatattggaggatca
caaggatatgatgaaatggaaccagcagcaaagaggtgctatctggaaagagagcaaggc
gaaaaaattattcaggagtttttatccaaggtgaagcaagtgccttttactgaaatgtca
gaagaaaacatcacaatgaagttaaaacagctgaaagctgaggtaatagcaaagaataat
agttttgtaaatgaaatcatttcacgaatcaaagtttctacatga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (7)   
   UniProt (2)   
   RefSeq(pep) (5)   
DNA sequence (7)   
   RefSeq(nuc) (5)   
   GenBank (1)   
   EMBL (1)   
Protein domain (7)   
   Pfam (7)   
All databases (39)   

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