KEGG   Canis lupus familiaris (dog): 494006
Entry
494006            CDS       T01007                                 
Symbol
MRE11
Name
(RefSeq) double-strand break repair protein MRE11 isoform X1
  KO
K10865  double-strand break repair protein MRE11
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa03440  Homologous recombination
cfa03450  Non-homologous end-joining
cfa04218  Cellular senescence
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03440 Homologous recombination
    494006 (MRE11)
   03450 Non-homologous end-joining
    494006 (MRE11)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    494006 (MRE11)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:cfa03032]
    494006 (MRE11)
   03400 DNA repair and recombination proteins [BR:cfa03400]
    494006 (MRE11)
DNA replication proteins [BR:cfa03032]
 Eukaryotic type
  DNA Replication Termination Factors
   MRN complex
    494006 (MRE11)
DNA repair and recombination proteins [BR:cfa03400]
 Eukaryotic type
  DSBR (double strand breaks repair)
   HR (homologous recombination)
    MRN(MRX) complex
     494006 (MRE11)
    BRCA1-C complex
     494006 (MRE11)
   NHEJ (non-homologous end-joining)
    MRX complex
     494006 (MRE11)
SSDB
Motif
Pfam: Mre11_DNA_bind Metallophos
Other DBs
NCBI-GeneID: 494006
NCBI-ProteinID: XP_005633408
Ensembl: ENSCAFG00000004162
VGNC: 43361
UniProt: A0A8C0SYU1
Position
21:6459592..6538889
AA seq 708 aa
MSPADTLDDENTFKILVATDIHLGFMEKDAVRGNDTYVTLDEILRLAQENEVDFILLGGD
LFHENKPSRKTLHTCLELLRKYCMGDRPVQFEILSDQSVNFGFSKFPWVNYQDGNLNISI
PVFSIHGNHDDPTGADALCALDVLSCAGFVNHFGRSMSVEKIDISPVLLQKGSTKIALYG
LGSIPDERLYRMFVNKKVTMLRPKEDENSWFNLFVIHQNRSKHGNTNFIPEQFLDDFIDL
VIWGHEHECKIAPTKNEQQLFYVSQPGSSVVTSLSPGEAVKKHVGLLRIKGRKMNMQKIP
LNTVRQFFMEDVVLADHPEIFNPDNPKVTQAIQSFCLEKIKEMLENAERERLGNSQQPEK
PLIRLRVDYSGGFEPFSVLRFSQKFVDRVANPKDVIHFFRHREQKEKTGEEINFGKLITK
PSEGTTLRVEDLVKQYFQTAEKNVQLSLLTERGMGEAVQEFVDKEEKDAIEELVKYQLEK
TQRFLKERHIDALEEKIDEEVRRFRESRQKNTNEEDDEVREAMTRARALRFQSEDSASAF
SAEDLMSIDLAEQMADDSDEDTSAAASRGRGRGRGRRGGRGQNSALRGGSQRGRVGTGLE
TSTRGRSSKATTSTSRNMSIIDAFKSTRQQPSRNVATKNYSEVIEVDESDVEEDIFPTTS
KTEQRWSSTSSSKRMSQSQIAKGVDFESDEDDDDDPFMNINSLRRNRR
NT seq 2127 nt   +upstreamnt  +downstreamnt
atgagtcctgcagatacccttgatgatgaaaatacctttaaaatcttagttgcaacagat
attcatctgggatttatggagaaagatgcagtcagaggaaatgatacgtatgtaacactg
gatgagattttaagacttgcccaagaaaatgaagtggattttattttgttaggtggtgat
ctttttcatgaaaataagccctcaagaaaaacattacatacctgcctcgagttattaaga
aaatattgcatgggtgatcgtcctgtacagtttgaaattctcagcgatcagtcagtcaac
tttggttttagtaagtttccatgggtgaactaccaagatggcaatctcaacatttcgatt
ccagtgtttagtattcatggcaatcatgatgatcccacaggggcagatgcactctgcgcc
ctggatgttttaagttgtgctggatttgtaaatcactttggacgttcaatgtctgtggag
aagatagacatcagtccagttttactccaaaaaggaagcacaaaaattgctctatatggc
ttagggtccattccagatgagaggctctatcgaatgtttgtcaataaaaaagtaacaatg
ttgagaccaaaagaagatgagaactcttggtttaacttatttgtgattcatcagaacagg
agtaaacatggaaatactaacttcattccagaacaatttttggatgacttcattgatctt
gttatctggggccatgaacatgagtgtaaaatagctccaaccaaaaatgaacaacaactc
ttttatgtatcccaacctggaagttcagtggttacttctctttccccaggagaagctgta
aagaaacacgtcggtttgctgcgtatcaaaggaaggaaaatgaatatgcagaaaatccct
cttaacacagttcggcagtttttcatggaggatgttgttctggctgaccatccagagatt
tttaacccagataatcccaaagtaacccaggccattcagagcttctgtttggagaagatt
aaagaaatgcttgaaaatgctgaacgagaacgtctgggaaattctcaacagccagagaag
cctcttatacgactgcgagtggactatagtggaggttttgagcctttcagtgttcttcgc
tttagccagaaatttgtggatcgggtagctaatccaaaagatgttatccattttttcagg
catagagaacaaaaggagaagacgggagaagagatcaactttgggaagctcattacaaaa
ccttcagaaggaacaaccctaagagtagaagaccttgtaaaacagtattttcaaactgca
gaaaagaatgtacagctctcacttctaacagaaaggggaatgggtgaagcagtacaggaa
tttgtggacaaggaagaaaaagatgccatagaggagttagtgaaataccagttggaaaaa
acacaacgatttcttaaagaacgtcatattgatgccctagaagagaaaatcgatgaagag
gtacgccgtttcagagaaagcagacaaaaaaacactaatgaagaagatgatgaagttcga
gaggctatgacgagggccagagccctcagatttcagtctgaggactctgcttctgccttt
agtgctgaggaccttatgagtatagatttggcagaacagatggctgatgactctgatgag
gacacctcagcagcagccagtagaggaagaggccggggccgaggccgacgaggaggaaga
gggcagaattcagccttgagaggagggtctcagagaggaagagtaggcactggtctggag
acttctactcgaggcagaagttcaaaggccactacgtcaacatctagaaacatgtctatt
atagatgcctttaaatctacaagacagcagccgtcccgaaatgttgctactaagaattat
tcagaggtgattgaggtggatgagtcagatgtggaagaagacatttttcctaccacttca
aaaacagaacaaaggtggtcgagcacatcatcaagcaagcgcatgtcccagagccaaata
gctaaaggggtcgattttgaatcagatgaggatgacgatgatgatccttttatgaacatt
aattctttaagaagaaacagaagataa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   RefGene (18)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (21)   
   UniProt (1)   
   RefSeq(pep) (20)   
DNA sequence (22)   
   RefSeq(nuc) (20)   
   GenBank (1)   
   EMBL (1)   
Protein domain (2)   
   Pfam (2)   
All databases (76)   

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