KEGG   Canis lupus familiaris (dog): 494010
Entry
494010            CDS       T01007                                 
Symbol
CYP1A2
Name
(RefSeq) cytochrome P450 1A2 precursor
  KO
K07409  cytochrome P450 family 1 subfamily A2 [EC:1.14.14.1]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa00140  Steroid hormone biosynthesis
cfa00232  Caffeine metabolism
cfa00380  Tryptophan metabolism
cfa00591  Linoleic acid metabolism
cfa00830  Retinol metabolism
cfa00980  Metabolism of xenobiotics by cytochrome P450
cfa00982  Drug metabolism - cytochrome P450
cfa01100  Metabolic pathways
cfa05204  Chemical carcinogenesis - DNA adducts
cfa05207  Chemical carcinogenesis - receptor activation
cfa05208  Chemical carcinogenesis - reactive oxygen species
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    494010 (CYP1A2)
   00591 Linoleic acid metabolism
    494010 (CYP1A2)
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    494010 (CYP1A2)
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    494010 (CYP1A2)
  09110 Biosynthesis of other secondary metabolites
   00232 Caffeine metabolism
    494010 (CYP1A2)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    494010 (CYP1A2)
   00982 Drug metabolism - cytochrome P450
    494010 (CYP1A2)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    494010 (CYP1A2)
   05207 Chemical carcinogenesis - receptor activation
    494010 (CYP1A2)
   05208 Chemical carcinogenesis - reactive oxygen species
    494010 (CYP1A2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:cfa00199]
    494010 (CYP1A2)
Enzymes [BR:cfa01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     494010 (CYP1A2)
Cytochrome P450 [BR:cfa00199]
 Cytochrome P450, animal type
  CYP1 family
   494010 (CYP1A2)
SSDB
Motif
Pfam: p450 Sec8_N
Other DBs
NCBI-GeneID: 494010
NCBI-ProteinID: NP_001008720
Ensembl: ENSCAFG00000017941
VGNC: 50333
UniProt: Q5R2U2
Position
30:37751388..37757086
AA seq 512 aa
MALSQMATELLLASTIFCLVLWVVKAWQPRLPKGLKSPPGPWGWPLLGNVLTLGKSPHLA
LSRLSQRYGDVLQIRIGSTPVLVLSGLDTIRQALVRQGDDFKGRPDLYSFSLVTDGQSLT
FSPDSGPVWAARRRLAQNALNTFSIASDPASSCSCYLEEHVSKEAEALLSRLQEQMAEVG
RFDPYNQVLMSVANVIGAMCFGHHFSQRSEEMLPLLMSSSDFVETVSNGNPVDFFPILQY
MPNSALQRFKNFNQTFVQSLQKIVQEHYQDFDERSVQDITGALLKHNEKSSRASDGHIPQ
EKIVNLINDIFGAGFDTVTTAISWSLMYLVANPEIQRKIQKELDTVIGRARQPRLSDRPQ
LPLMEAFILEIFRHTSFVPFTIPHSTTKDTTLKGFYIPKECCVFINQWQVNHDQQVWGDP
FAFRPERFLTADGTAINKTLSEKVMLFGMGKRRCIGEVLAKWEIFLFLAILLQRLEFSVP
AGVRVDLTPIYGLTMKHTRCEHVQARPRFSIK
NT seq 1539 nt   +upstreamnt  +downstreamnt
atggcattgtcccagatggccacagagcttctcctggcctccaccatcttctgcttggta
ctctgggtggtcaaggcctggcagcctcggcttcccaaaggcctgaagagtccaccgggg
ccctggggctggcccctgctcgggaacgtgctgaccttgggcaagagcccccacctggcg
ctgtccaggctgagccagcgttatggggacgtgctgcagatccgcatcggctccaccccc
gtgctggtgctcagtggcctggacaccatccggcaggccctggtgcgccagggggatgat
ttcaagggccggcccgacctctacagcttctctctggtgaccgacggccaaagcctgacc
ttcagcccagactccggaccagtgtgggctgcgcgcaggcgcctggctcagaacgcgctc
aacaccttctccattgcctccgacccggcttcctcgtgctcttgctacctggaagagcat
gtgagcaaggaggccgaggcccttctcagcaggctgcaggagcagatggcagaggttggg
cgctttgatccctacaaccaagtgctgatgtcagtggccaatgtcattggtgcaatgtgc
tttgggcaccacttctctcagagaagtgaggaaatgctccccctcctaatgagctccagt
gattttgtggagaccgtctccaacgggaacccggtggactttttccccattctccaatat
atgcccaactcagccctgcagagattcaagaacttcaaccagacgttcgtgcagtccctg
cagaaaattgtccaggaacactatcaagactttgatgagcgcagtgtccaggacatcaca
ggcgccctcttgaagcacaatgagaagagctccagggctagtgatggccacatcccccaa
gagaagattgtcaaccttatcaacgacatttttggggccggatttgacactgtcacaacg
gccatttcctggagtcttatgtaccttgtggcaaaccctgagatacagagaaagatccag
aaggagttggacacggtgattggcagggcacggcagcctcgcctctctgacaggccccag
ctgcccttaatggaggccttcatcctggagatcttccgacacacctcctttgtccccttc
accatcccccacagcacaacaaaggacacaaccttaaagggcttctacatccccaaggaa
tgctgtgtcttcataaaccagtggcaggtcaatcatgaccaacaggtgtggggggatcca
tttgcattccggccagagcgattcctcactgcagatggcaccgccatcaacaagaccttg
agtgagaaggtgatgctctttggcatgggcaagcgccggtgcataggagaggtcctggcc
aagtgggagatcttcctcttcctagccatcttgctgcagcggctggagttcagcgtgcca
gcaggtgtgagagtagacctaacccccatctatgggctgaccatgaagcacacccgctgt
gagcatgtccaggcacggccacgcttctccatcaagtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (11)   
   KEGG PATHWAY (11)   
Chemical substance (37)   
   KEGG COMPOUND (37)   
Chemical reaction (20)   
   KEGG ENZYME (1)   
   KEGG REACTION (19)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (18)   
   RefSeq(nuc) (2)   
   GenBank (8)   
   EMBL (8)   
Protein domain (2)   
   Pfam (2)   
All databases (103)   

Download RDF
DBGET integrated database retrieval system