KEGG   Canis lupus familiaris (dog): 608738
Entry
608738            CDS       T01007                                 
Symbol
NEDD4
Name
(RefSeq) E3 ubiquitin-protein ligase NEDD4 isoform X1
  KO
K10591  E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04120  Ubiquitin mediated proteolysis
cfa04144  Endocytosis
cfa04530  Tight junction
cfa05169  Epstein-Barr virus infection
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    608738 (NEDD4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    608738 (NEDD4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    608738 (NEDD4)
 09160 Human Diseases
  09172 Infectious disease: viral
   05169 Epstein-Barr virus infection
    608738 (NEDD4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cfa04131]
    608738 (NEDD4)
   04121 Ubiquitin system [BR:cfa04121]
    608738 (NEDD4)
   03029 Mitochondrial biogenesis [BR:cfa03029]
    608738 (NEDD4)
Enzymes [BR:cfa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.26  HECT-type E3 ubiquitin transferase
     608738 (NEDD4)
Membrane trafficking [BR:cfa04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Ubiquitin E3 ligases
    608738 (NEDD4)
Ubiquitin system [BR:cfa04121]
 Ubiquitin ligases (E3)
  HECT type E3
   608738 (NEDD4)
Mitochondrial biogenesis [BR:cfa03029]
 Mitochondrial quality control factors
  Mitochondrial dynamics
   Morphogenesis factors
    608738 (NEDD4)
SSDB
Motif
Pfam: HECT WW
Other DBs
NCBI-GeneID: 608738
NCBI-ProteinID: XP_005638494
Ensembl: ENSCAFG00000015977
VGNC: 59121
UniProt: A0A8C0NKI0
Position
30:complement(21088774..21211642)
AA seq 1323 aa
MAQSLRLHFAARRSNTYPLSETSGDDLDSNVHMCFKRPTRISTSNVVQMKLTPRQTALAP
LIQENVNSQERSSVPSPENVNKKSSCLQISLQPTRYSGCLQSGNVLADGDDASFTSVFKD
GIYNNAVADNELNAVNDGNLVSSSAIHSGSLSNFSTSENGSYSSNGSDYGSCTSITSGGS
YTNSIISDSSGYTFPPTDDTFFGGNLSSDSTSNRSVPNRNTTPCDIFSRSPSTVPFVQDD
LEHGLEIMKLPVTRNSKIPLKRCSSLVIFPRSPLNTPPTSPTSTDVLPSKGSYQTSHQFI
ISPSEIAHSEDGSSTKGFLSTAVNGLRLSKTICTPGEVRDIRPLHRKGSLQKKIVIANDS
LNQNVREKSSEGFSCVSVHFTQQKATTLDCETASGDCKPEMSEIKLNSHSECIKLMQRTS
ACLPSSQHLDYQININGQLERPNLQINKNHAILQRSVSLGGTYPNVSCLSSLKHNCSKGG
PSQLLIKFAPGNEDKVDNLSRDSNRDFTNELSNSLKHSCKTRDDFLGQVDVPLYPLPTEN
PRMERPYTFKDFVLHPRSHKSRVKGYLRLKMTYLPKTSGSEEDNAEQAEELEPGWVVLDQ
PDAACHLQQQQEPSPLPPGWEERQDILGRTYYVNHESRRTQWKRPTAQDNLTDAENGNMQ
LQAQRAFTTRRQISEETESVDNRESSESWEIIREDEATMYSNQAFPSPPASNNLDVQTHL
AEELNARLTICRNSATSQPVSSSNHSSRRGSLQAYTFEEQPTLPVLLPTSSGLPPGWEEK
QDERGRSYYVDHNSRTTTWTKPVVQATVETSQLQPSQSAACPQPQVPLSESAQQGTQAAE
MEQGFLPKGWEVRHAPNGRPFFIDHNTKTTTWEDPRLKIPAHLRGKMSLDSSNDLGPLPP
GWEERTHTDGRIFYINHNIKRTQWEDPRLQNVAITGPAVPYSRDYKRKYEFFRRKLKKQN
DIPNKFEMKLRRATVLEDSYRRIMGVKRADFLKARLWIEFDGEKGLDYGGVAREWFFLIS
KEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFKFIGRVAGMAVYHGKLLDGFFI
RPFYKMMLHKPITLHDMESVDGEYYNSLRWILENDPTELDLRFVIDEELFGQTHQHELKI
GGSEIVVTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIFDENELELLM
CGLGDVDVNDWREHTKYKNGYSVNHQVIQWFWKAVLMMDSEKRIRLLQFVTGTSRVPMNG
FAELYGSNGPQSFTVEQWGTPEKLPRAHTCFNRLDLPPYESFEELWDKLQMAIENTQGFD
GVD
NT seq 3972 nt   +upstreamnt  +downstreamnt
atggcacaaagcttacgattgcactttgcagccagaagaagcaatacttatcctttgtca
gaaacctccggagatgatttggatagcaatgttcacatgtgcttcaaaagaccaacacgg
atttcaacgtctaacgttgttcaaatgaagctgactcctagacagactgcactagctccg
ttgatacaggaaaacgttaactctcaggaaagatcatctgttccttcacctgaaaatgtt
aataaaaagagcagctgtctgcagatttcactacaaccaacaaggtacagtggatgtctt
cagtctggcaatgtcttagctgatggtgatgatgcttcatttacatctgtctttaaggat
ggcatttacaacaatgctgtggctgataatgagctgaatgctgtgaatgatggtaacctt
gtaagcagttcggccattcacagtgggagcctcagtaacttttccaccagtgagaatggg
tcttacagcagcaatggtagtgattatggatcatgcacaagtatcacaagtggtggttcc
tacacaaacagtatcatcagtgacagcagtggttatacttttccaccaactgatgatact
ttttttggtggaaatttatcttctgacagcacctccaatagaagtgtgccaaacaggaat
actactccatgtgacattttttcaagaagtccaagtaccgttccttttgtccaggatgac
ttggagcatggactagaaattatgaaattgccagtgaccaggaactcgaaaattccacta
aaacgttgttcatccttagtcatttttcctaggagtcctttaaataccccaccgacttct
ccaacaagtacagacgttcttccaagcaaaggatcctatcaaacctcacaccaatttatt
atttctcctagtgaaattgcccacagtgaagatggtagtagcactaagggatttctttca
acagctgtcaatggacttcggttatctaaaacaatctgtactcccggagaagtgagagac
atacgaccacttcacaggaagggttcattacaaaagaaaattgttattgcgaatgatagt
ctgaatcagaatgtccgtgaaaagtcgtctgaagggttttcttgtgtttcagtgcatttc
acccaacaaaaagcaactacattagattgtgaaacagcaagtggtgattgcaaaccagag
atgtcagaaatcaagcttaattctcattcagagtgcattaagcttatgcagaggacatct
gcatgtttaccatcctctcaacacctagattaccaaataaatatcaatggacagttggaa
agaccaaatttacagataaacaaaaaccatgctattttacagagaagtgtttcattggga
ggaacttacccaaatgtttcctgtttatccagcctcaagcacaattgttctaagggggga
ccatcacaattactcataaaatttgcacctggaaatgaagataaagttgataacttatca
agagacagtaacagagatttcacaaatgaactatctaattctttaaagcattcttgtaag
accagagatgatttcctaggtcaagtggatgttcctctttatccattaccgacagaaaat
ccaagaatggagagaccatatacgtttaaggattttgttcttcacccaagaagtcacaaa
tcaagagttaaaggttatttgagattaaaaatgacttatttacctaaaaccagtggctca
gaagaagataacgcagaacaggccgaggaactagagcctggctgggttgttttggaccaa
ccggatgctgcctgccatttgcagcagcagcaagaaccttctcctctacctccaggatgg
gaagagaggcaggatattcttggaaggacctactatgtaaaccatgaatctagaagaaca
cagtggaaaagaccaaccgctcaggacaacctaactgatgctgagaatggtaacatgcaa
ctgcaagcacagcgtgcatttactaccagacggcagatatctgaggaaacagaaagtgtg
gataatcgagagtcttccgagagctgggaaattataagagaagatgaagccaccatgtat
agcaatcaggccttcccatcacctccagcatcaaataacttggatgttcagactcatctt
gcagaagaattgaatgccagactcacaatttgtagaaactcagccaccagccagccagta
tccagctcaaatcattccagcagaagaggcagcttacaagcctatacttttgaggaacag
cctacacttcctgtgcttttgcctacttcatctggattaccaccaggttgggaggaaaaa
caagatgaaagaggaagatcatattatgtagatcacaattccagaactactacctggaca
aagcccgttgtacaggccacggtggagaccagtcagctgcagccaagccagagtgcggca
tgtcctcaaccacaggtccccttgagtgagtcagcgcagcaggggacccaggcggctgaa
atggagcaaggattcctccctaaaggctgggaagtccggcatgcgccaaatgggaggcct
ttctttattgaccacaacaccaaaaccactacctgggaagatccaagactgaaaattcca
gctcatctgagaggaaagatgtcactggattcttccaatgatctggggcctttacctcca
ggatgggaagaaagaactcatacagatggaagaatcttctacataaatcacaatataaaa
agaacacaatgggaagatcctcggttgcaaaatgtagcaataactggaccagcagtgccc
tactccagggattacaaaagaaagtatgagttcttccgacgaaagttgaagaagcagaac
gacattccaaacaaatttgaaatgaaacttcgccgtgcaactgtccttgaggactcttac
aggaggattatgggtgtcaagagagcggatttcctcaaggctcgactgtggattgagttc
gatggtgaaaagggattagattacggaggagtcgctagagaatggtttttcctgatctca
aaggaaatgtttaacccttattatgggttgtttgaatattctgctacggataattacacc
ctacagataaatccaaactctggattgtgtaacgaggatcacctctcttacttcaagttt
attggccgagtagctggaatggcagtttatcatggcaaactgttggatggtttcttcatc
cgcccattttacaagatgatgctacacaaaccaataacacttcatgatatggaatcggtg
gatggtgaatattacaattcactaagatggattcttgaaaatgatccaacagaattggac
ctcaggtttgtcatagatgaagaactttttggacagacacatcaacatgaattgaaaatt
ggtggatcagaaatagttgtcaccaataagaacaaaaaggaatatatttatcttgtaata
cagtggcgatttgtaaaccgaatccagaagcaaatggctgcttttaaagagggatttttt
gaactaataccacaggatctcatcaaaattttcgatgaaaatgaactagagcttcttatg
tgtggattgggagatgtcgatgtgaatgactggagagaacacacaaaatataagaatggc
tacagtgtgaatcatcaagtcatacagtggttctggaaggctgttctaatgatggattca
gaaaaaagaataagattacttcagtttgtcactggtacatctcgagtgcctatgaatgga
tttgctgaactctatggctcaaatggaccacagtcatttacagttgaacagtggggtacc
ccggaaaagctgccaagagcccatacatgctttaatcgcttggacttgccaccctatgaa
tcatttgaagaattatgggataaactgcagatggcaattgagaacactcaaggctttgat
ggcgttgattag

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   RefGene (18)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (26)   
   UniProt (1)   
   RefSeq(pep) (25)   
DNA sequence (25)   
   RefSeq(nuc) (25)   
Protein domain (2)   
   Pfam (2)   
All databases (88)   

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