| Entry |
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| Name |
Cortisone;
17alpha,21-Dihydroxy-4-pregnene-3,11,20-trione;
Kendall's compound E;
Reichstein's substance Fa
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| Formula |
C21H28O5
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| Exact mass |
360.1937
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| Mol weight |
360.444
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| Structure |
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| Remark |
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| Reaction |
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| Pathway |
| map04960 | Aldosterone-regulated sodium reabsorption |
| map07225 | Glucocorticoid and mineralocorticoid receptor agonists/antagonists |
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| Module |
| M00109 | C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone |
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| Network |
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| Enzyme |
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| Brite |
Compounds with biological roles [BR:br08001]
Steroids
21-Carbon atoms
Pregnane derivatives
C00762 Cortisone
Hormones and transmitters
Steroid hormones
Glucocorticoids
C00762 Cortisone
Lipids [BR:br08002]
ST Sterol lipids
ST02 Steroids
ST0203 C21 steroids (gluco/mineralocorticoids, progestogins) and derivatives
C00762 Cortisone
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
H02 CORTICOSTEROIDS FOR SYSTEMIC USE
H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
H02AB Glucocorticoids
H02AB10 Cortisone
D07749 Cortisone (INN)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01B ANTIINFLAMMATORY AGENTS
S01BA Corticosteroids, plain
S01BA03 Cortisone
D07749 Cortisone (INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00509 Cortisone
D07749 Cortisone
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D07749 Cortisone (INN)
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| Other DBs |
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| KCF data |
ATOM 26
1 C1x C 5.6756 -16.9748
2 C5x C 5.6756 -18.3385
3 C2x C 6.8565 -19.0203
4 C2y C 8.0376 -18.3385
5 C1z C 8.0376 -16.9748
6 C1x C 6.8565 -16.2929
7 C1x C 9.2185 -19.0203
8 C1x C 10.3994 -18.3385
9 C1y C 10.3994 -16.9748
10 C1y C 9.2185 -16.2929
11 C1y C 11.5805 -16.2929
12 C1z C 11.5805 -14.9293
13 C1x C 10.3994 -14.2474
14 C5x C 9.2185 -14.9293
15 C1x C 13.9424 -16.2929
16 C1x C 13.9424 -14.9293
17 C1z C 12.7614 -14.2474
18 C1a C 8.0376 -15.6111
19 C1a C 11.5805 -13.5656
20 C5a C 12.7614 -12.5429
21 O5x O 4.4946 -19.0203
22 O5x O 8.0395 -14.2486
23 C1b C 13.9464 -11.8588
24 O5a O 11.5844 -11.8633
25 O1a O 13.9424 -13.5656
26 O1a O 15.1128 -12.5323
BOND 29
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 9 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 10 14 1
17 11 15 1
18 15 16 1
19 16 17 1
20 12 17 1
21 5 18 1 #Up
22 12 19 1 #Up
23 17 20 1 #Up
24 2 21 2
25 14 22 2
26 20 23 1
27 20 24 2
28 17 25 1 #Down
29 23 26 1
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