KEGG   COMPOUND: C06922
Entry
C06922                      Compound                               
Name
Clotrimazole
Formula
C22H17ClN2
Exact mass
344.108
Mol weight
344.8368
Structure
Remark
Same as: D00282
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A01 STOMATOLOGICAL PREPARATIONS
   A01A STOMATOLOGICAL PREPARATIONS
    A01AB Antiinfectives and antiseptics for local oral treatment
     A01AB18 Clotrimazole
      D00282  Clotrimazole (JP18/USP/INN) <JP/US>
 D DERMATOLOGICALS
  D01 ANTIFUNGALS FOR DERMATOLOGICAL USE
   D01A ANTIFUNGALS FOR TOPICAL USE
    D01AC Imidazole and triazole derivatives
     D01AC01 Clotrimazole
      D00282  Clotrimazole (JP18/USP/INN) <JP/US>
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G01 GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
   G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
    G01AF Imidazole derivatives
     G01AF02 Clotrimazole
      D00282  Clotrimazole (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
 Dermatological Agents
  Topical Anti-infectives
   Antifungals, dermatological
    Clotrimazole
     D00282  Clotrimazole (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  25  Urogenital and anal organ agents
   252  Genital organ agents
    2529  Others
     D00282  Clotrimazole (JP18/USP/INN)
  26  Epidermides
   265  Antiparasitic dermatosis agents
    2655  Imidazoles
     D00282  Clotrimazole (JP18/USP/INN)
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   629  Miscellaneous
    6290  Miscellaneous
     D00282  Clotrimazole (JP18/USP/INN)
Classification of Japanese OTC drugs [BR:br08313]
 Drugs for women
  51 Other drugs for women
   D00282  Clotrimazole (JP18/USP/INN)
 Agents for integumentary system
  58 Ringworm drugs
   D00282  Clotrimazole (JP18/USP/INN)
Risk category of Japanese OTC drugs [BR:br08312]
 First-class OTC drugs
  Inorganic and organic chemicals
   Clotrimazole
    D00282  Clotrimazole (JP18/USP/INN)
 Second-class OTC drugs
  Inorganic and organic chemicals
   Clotrimazole
    D00282  Clotrimazole (JP18/USP/INN)
Drug groups [BR:br08330]
 Antifungal
  DG01883  Imidazole antifungal
   D00282  Clotrimazole
 Metabolizing enzyme inhibitor
  DG02852  CYP3A/CYP3A4 inhibitor
   DG01522  CYP3A4 inhibitor
    D00282  Clotrimazole
Drug classes [BR:br08332]
 Antifungal
  DG01883  Imidazole antifungal
   D00282  Clotrimazole
Antimicrobials [BR:br08307]
 Antifungals
  Ergosterol biosynthesis inhibitor
   Imidazole
    D00282  Clotrimazole (JP18/USP/INN) <JP/US>
Antimicrobials abbreviations [BR:br08327]
 Antifungals
  Ergosterol biosynthesis inhibitor
   Imidazole
    D00282  Clotrimazole (JP17/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00282  Clotrimazole
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D00282
Rx-to-OTC switch list in the USA [br08315.html]
 D00282
Rx-to-OTC switch list in Japan [br08314.html]
 D00282
Other DBs
CAS: 23593-75-1
PubChem: 9139
ChEBI: 3764
PDB-CCD: CL6[PDBj]
NIKKAJI: J3.156I
KCF data

ATOM        25
            1   C1d C    24.6753  -14.4492
            2   C8y C    22.9469  -14.3852
            3   N4y N    26.5497  -14.3852
            4   C8y C    24.6753  -15.7164
            5   C8y C    24.6812  -13.2056
            6   C8y C    22.2695  -13.1705
            7   C8x C    22.2462  -15.5822
            8   C8x C    23.4899  -16.3996
            9   C8x C    25.8606  -16.3996
            10  C8x C    25.9074  -12.5049
            11  C8x C    23.4666  -12.5049
            12  C8x C    20.8798  -13.1590
            13  X   Cl   22.2521  -11.9559
            14  C8x C    20.8507  -15.5763
            15  C8x C    23.4899  -17.7660
            16  C8x C    25.8606  -17.7660
            17  C8x C    25.9016  -11.0917
            18  C8x C    23.4608  -11.0975
            19  C8x C    20.1676  -14.3559
            20  C8x C    24.6753  -18.4491
            21  C8x C    24.6753  -10.3910
            22  C8x C    27.3310  -15.5439
            23  N5x N    28.6764  -15.1570
            24  C8x C    28.7242  -13.7578
            25  C8x C    27.4083  -13.2800
BOND        28
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     1   5 1
            5     2   6 2
            6     2   7 1
            7     4   8 1
            8     4   9 2
            9     5  10 2
            10    5  11 1
            11    6  12 1
            12    6  13 1
            13    7  14 2
            14    8  15 2
            15    9  16 1
            16   10  17 1
            17   11  18 2
            18   12  19 2
            19   15  20 1
            20   17  21 2
            21   14  19 1
            22   16  20 2
            23   18  21 1
            24    3  22 1
            25   22  23 2
            26   23  24 1
            27   24  25 2
            28    3  25 1

» Japanese version

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Drug (1)   
   KEGG DRUG (1)   
Chemical substance (6)   
   PubChem (1)   
   ChEBI (1)   
   HMDB (1)   
   HSDB (1)   
   NIKKAJI (1)   
   PDB-CCD (1)   
All databases (7)   

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