| | COMPOUND: C06924 | |
Entry |
|
Name |
|
Formula |
C18H19ClN4
|
Exact mass |
326.1298
|
Mol weight |
326.8233
|
Structure |
|
Remark |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05A ANTIPSYCHOTICS
N05AH Diazepines, oxazepines, thiazepines and oxepines
N05AH02 Clozapine
D00283 Clozapine (JAN/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Antipsychotics
Treatment-Resistant
Clozapine
D00283 Clozapine (JAN/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
117 Psychotropics
1179 Others
D00283 Clozapine (JAN/USP/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01476 Dopamine D4-receptor antagonist
D00283 Clozapine
DG03200 Antipsychotic agent
DG03064 Atypical antipsychotic
D00283 Clozapine
Metabolizing enzyme substrate
DG01892 CYP1A2 substrate
D00283 Clozapine
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
D00283 Clozapine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA2
D00283 Clozapine (JAN/USP/INN) <JP/US>
Dopamine
DRD4
D00283 Clozapine (JAN/USP/INN) <JP/US>
Serotonin
HTR2A
D00283 Clozapine (JAN/USP/INN) <JP/US>
HTR2C
D00283 Clozapine (JAN/USP/INN) <JP/US>
Ion channels
Ligand-gated ion channels
Serotonin
HTR3
D00283 Clozapine (JAN/USP/INN) <JP/US>
New drug approvals in Japan [br08318.html]
Drugs with new active ingredients
D00283
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00283
Pharmacogenomic biomarkers [br08341.html]
Polymorphisms and mutations affecting drug response
D00283
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Other DBs |
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KCF data |
ATOM 23
1 C2y C 23.0142 -13.7220
2 C8y C 22.1726 -12.6130
3 C8y C 22.5076 -11.2569
4 N1x N 23.7680 -10.6791
5 N2x N 24.4193 -13.7472
6 C8y C 25.0209 -11.3010
7 C8y C 25.3073 -12.6690
8 C8x C 21.5010 -10.2890
9 C8x C 20.1597 -10.6769
10 C8x C 19.8247 -12.0330
11 C8x C 20.8313 -13.0006
12 C8x C 26.6378 -13.1059
13 C8y C 27.6814 -12.1720
14 C8x C 27.3952 -10.8040
15 C8x C 26.0645 -10.3671
16 N1y N 22.3801 -14.9710
17 C1x C 20.9792 -14.9710
18 C1x C 20.2788 -16.1842
19 N1y N 20.9792 -17.3976
20 C1x C 22.3801 -17.3976
21 C1x C 23.0805 -16.1842
22 X Cl 29.0355 -12.6169
23 C1a C 20.2726 -18.6209
BOND 26
1 3 4 1
2 1 5 2
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 1
8 3 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 2 11 2
13 7 12 2
14 12 13 1
15 13 14 2
16 14 15 1
17 6 15 2
18 1 16 1
19 16 17 1
20 17 18 1
21 18 19 1
22 19 20 1
23 20 21 1
24 16 21 1
25 13 22 1
26 19 23 1
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