KEGG   COMPOUND: C07023
Entry
C07023                      Compound                               
Name
Granisetron
Formula
C18H24N4O
Exact mass
312.195
Mol weight
312.4094
Structure
Remark
Same as: D04370
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A04 ANTIEMETICS AND ANTINAUSEANTS
   A04A ANTIEMETICS AND ANTINAUSEANTS
    A04AA Serotonin (5HT3) antagonists
     A04AA02 Granisetron
      D04370  Granisetron (JAN/USAN/INN) <US>
USP drug classification [BR:br08302]
 Antiemetics
  Emetogenic Therapy Adjuncts
   Granisetron
    D04370  Granisetron (JAN/USAN/INN)
Drug groups [BR:br08330]
 Gastrointestinal agent
  DG01489  5-HT3-receptor antagonist
   DG00061  Granisetron
    D04370  Granisetron
  DG01762  Antiemetic
   DG00061  Granisetron
    D04370  Granisetron
 Metabolizing enzyme substrate
  DG01891  CYP1A1 substrate
   DG00061  Granisetron
    D04370  Granisetron
  DG01633  CYP3A/CYP3A4 substrate
   DG02913  CYP3A4 substrate
    DG00061  Granisetron
     D04370  Granisetron
Target-based classification of drugs [BR:br08310]
 Ion channels
  Ligand-gated ion channels
   Serotonin
    HTR3B
     D04370  Granisetron (JAN/USAN/INN) <US>
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D04370
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D04370
Other DBs
CAS: 109889-09-0
PubChem: 9235
ChEBI: 184693 5537
NIKKAJI: J258.427A
KCF data

ATOM        23
            1   C1x C    26.5300  -16.4500
            2   C1x C    26.6700  -15.5400
            3   C1y C    27.6500  -16.1700
            4   C1y C    27.9300  -15.0500
            5   N1y N    26.7400  -13.7900
            6   C1x C    29.4000  -16.1700
            7   C1x C    29.1200  -15.0500
            8   C1y C    30.3800  -16.6600
            9   N1b N    31.4300  -17.5700
            10  C5a C    32.5500  -17.5700
            11  C8y C    33.1100  -16.5200
            12  O5a O    33.1100  -18.6200
            13  C1a C    26.0400  -12.6700
            14  C1x C    25.5500  -15.0500
            15  C8y C    34.4400  -16.5200
            16  C8y C    34.8600  -15.2600
            17  N4y N    33.8100  -14.4900
            18  N5x N    32.6900  -15.2600
            19  C8x C    35.3500  -17.5000
            20  C8x C    36.6100  -17.2200
            21  C8x C    37.0300  -15.9600
            22  C8x C    36.1200  -14.9800
            23  C1a C    33.8100  -13.1600
BOND        26
            1     1   3 1
            2     2   4 1
            3     3   5 1
            4     3   6 1
            5     4   7 1
            6     6   8 1
            7     8   9 1
            8     9  10 1
            9    10  11 1
            10   10  12 2
            11    4   5 1
            12    7   8 1
            13    5  13 1
            14    2  14 1
            15    1  14 1
            16   11  15 1
            17   15  16 1
            18   16  17 1
            19   17  18 1
            20   11  18 2
            21   15  19 2
            22   19  20 1
            23   20  21 2
            24   21  22 1
            25   16  22 2
            26   17  23 1

» Japanese version

  All links  
Drug (1)   
   KEGG DRUG (1)   
Chemical substance (5)   
   PubChem (1)   
   ChEBI (2)   
   HMDB (1)   
   NIKKAJI (1)   
All databases (6)   

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