KEGG   COMPOUND: C07074
Entry
C07074                      Compound                               
Name
Lovastatin
Formula
C24H36O5
Exact mass
404.2563
Mol weight
404.5396
Structure
Sequence
  Gene
lovB(LNKS) [UP:Q9Y8A5]; LovC(LNKS)
  Organism
Aspergillus terreus
  Type
PK
Remark
Same as: D00359
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C10 LIPID MODIFYING AGENTS
   C10A LIPID MODIFYING AGENTS, PLAIN
    C10AA HMG CoA reductase inhibitors
     C10AA02 Lovastatin
      D00359  Lovastatin (USP/INN) <US>
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Dyslipidemics, HMG CoA Reductase Inhibitors
   Lovastatin
    D00359  Lovastatin (USP/INN)
Drug groups [BR:br08330]
 Hypolipidemic agent
  DG01946  Hypolipidemic agent
   DG01660  HMG-CoA reductase inhibitor
    D00359  Lovastatin
 Metabolizing enzyme substrate
  DG01633  CYP3A/CYP3A4 substrate
   DG02913  CYP3A4 substrate
    D00359  Lovastatin
Drug classes [BR:br08332]
 Cardiovascular agent
  DG01946  Hypolipidemic agent
   D00359  Lovastatin
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases (EC1)
   Dehydrogenases
    HMGCR
     D00359  Lovastatin (USP/INN) <US>
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D00359
Prodrugs [br08324.html]
 D00359
Other DBs
CAS: 75330-75-5
PubChem: 9285
ChEBI: 40303
KNApSAcK: C00000547
PDB-CCD: 803[PDBj]
NIKKAJI: J22.276C
KCF data

ATOM        29
            1   C1y C    26.2681  -21.4649
            2   C1y C    25.0617  -20.7655
            3   C2y C    26.2624  -22.8577
            4   C1y C    27.4746  -20.7713
            5   O7a O    25.0617  -19.3726
            6   C1x C    23.8497  -21.4649
            7   C2x C    27.4629  -23.5627
            8   C2x C    25.0617  -23.5570
            9   C1b C    27.4804  -19.3785
            10  C1y C    28.6809  -21.4766
            11  C7a C    23.8555  -18.6733
            12  C1y C    23.8497  -22.8577
            13  C2x C    28.6751  -22.8694
            14  C1c C    22.6491  -19.3726
            15  O6a O    23.8613  -17.2805
            16  C1a C    22.6433  -23.5570
            17  C1b C    21.4427  -18.6733
            18  C1a C    22.6491  -20.7655
            19  C1a C    20.2364  -19.3669
            20  C1a C    29.8735  -20.7959
            21  C1b C    28.7140  -18.6619
            22  C1y C    28.7174  -17.2654
            23  O7x O    29.9267  -16.5712
            24  C7x C    29.9301  -15.1747
            25  C1x C    28.7224  -14.4735
            26  C1y C    27.5133  -15.1677
            27  C1x C    27.5098  -16.5641
            28  O6a O    31.1393  -14.4805
            29  O1a O    26.2978  -14.4619
BOND        31
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1 #Down
            5     2   6 1
            6     3   7 1
            7     3   8 2
            8     4   9 1 #Up
            9     4  10 1
            10    5  11 1
            11    6  12 1
            12    7  13 2
            13   11  14 1
            14   11  15 2
            15   12  16 1 #Down
            16   14  17 1
            17   14  18 1 #Up
            18   17  19 1
            19    8  12 1
            20   10  13 1
            21   10  20 1 #Up
            22    9  21 1
            23   22  21 1 #Down
            24   22  23 1
            25   23  24 1
            26   24  25 1
            27   25  26 1
            28   26  27 1
            29   22  27 1
            30   24  28 2
            31   26  29 1 #Up

» Japanese version

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Drug (1)   
   KEGG DRUG (1)   
Chemical substance (7)   
   PubChem (1)   
   ChEBI (1)   
   HMDB (1)   
   HSDB (1)   
   KNApSAcK (1)   
   NIKKAJI (1)   
   PDB-CCD (1)   
All databases (8)   

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