 | | COMPOUND: C07404 | |
| Entry |
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| Name |
Promethazine;
10-(2-Dimethylaminopropyl)phenothiazine
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| Formula |
C17H20N2S
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| Exact mass |
284.1347
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| Mol weight |
284.4191
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| Structure |
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| Remark |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D04 ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04A ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04AA Antihistamines for topical use
D04AA10 Promethazine
D00494 Promethazine (JAN/INN)
R RESPIRATORY SYSTEM
R06 ANTIHISTAMINES FOR SYSTEMIC USE
R06A ANTIHISTAMINES FOR SYSTEMIC USE
R06AD Phenothiazine derivatives
R06AD02 Promethazine
D00494 Promethazine (JAN/INN)
Risk category of Japanese OTC drugs [BR:br08312]
Designated second-class OTC drugs
Inorganic and organic chemicals
Promethazine
D00494 Promethazine (JAN/INN)
Second-class OTC drugs
Inorganic and organic chemicals
Promethazine
D00494 Promethazine (JAN/INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG00385 Promethazine
D00494 Promethazine
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
DG00385 Promethazine
D00494 Promethazine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D00494 Promethazine (JAN/INN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00494
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| Other DBs |
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| KCF data |
ATOM 20
1 N1y N 25.3291 -19.1045
2 C8y C 26.5689 -19.8030
3 C8y C 24.1359 -19.8030
4 C1b C 25.3291 -17.6902
5 C8y C 26.5689 -21.2116
6 C8x C 27.7621 -19.1045
7 C8y C 24.1359 -21.2116
8 C8x C 22.9369 -19.1045
9 C1c C 26.5340 -17.0033
10 S2x S 25.3291 -21.9041
11 C8x C 27.7621 -21.9041
12 C8x C 28.9670 -19.8030
13 C8x C 22.9369 -21.9041
14 C8x C 21.6971 -19.8030
15 N1c N 26.5340 -15.6820
16 C1a C 27.7272 -17.6902
17 C8x C 28.9670 -21.2116
18 C8x C 21.6971 -21.2116
19 C1a C 25.1953 -14.9079
20 C1a C 27.6690 -14.9428
BOND 22
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 2
5 2 6 1
6 3 7 2
7 3 8 1
8 4 9 1
9 5 10 1
10 5 11 1
11 6 12 2
12 7 13 1
13 8 14 2
14 9 15 1
15 9 16 1
16 11 17 2
17 13 18 2
18 15 19 1
19 15 20 1
20 7 10 1
21 12 17 1
22 14 18 1
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» Japanese version
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