Entry |
|
Name |
Perphenazine;
4-(3-(2-Chlorophenothiazin-10-YL)propyl)-1-piperazineethanol
|
Formula |
C21H26ClN3OS
|
Exact mass |
403.1485
|
Mol weight |
403.9686
|
Structure |
|
Remark |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05A ANTIPSYCHOTICS
N05AB Phenothiazines with piperazine structure
N05AB03 Perphenazine
D00503 Perphenazine (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Antiemetics
Antiemetics, Other
Perphenazine
D00503 Perphenazine (JP18/USP/INN)
Antipsychotics
1st Generation/Typical
Perphenazine
D00503 Perphenazine (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
117 Psychotropics
1172 Phenothiazines
D00503 Perphenazine (JP18/USP/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00875 Perphenazine
D00503 Perphenazine
DG03200 Antipsychotic agent
DG01905 Phenothiazine antipsychotics
DG00875 Perphenazine
D00503 Perphenazine
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
DG00875 Perphenazine
D00503 Perphenazine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D00503 Perphenazine (JP18/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00503 Perphenazine
D00503 Perphenazine tablets
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00503
Pharmacogenomic biomarkers [br08341.html]
Polymorphisms and mutations affecting drug response
D00503
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Other DBs |
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KCF data |
ATOM 27
1 C8x C 25.4800 -18.5500
2 C8x C 25.4800 -19.9500
3 C8x C 26.6700 -20.6500
4 C8y C 27.9300 -19.9500
5 C8y C 27.9300 -18.5500
6 C8x C 26.6700 -17.8500
7 S2x S 29.1200 -20.6500
8 C8y C 30.3100 -19.9500
9 C8y C 30.3100 -18.5500
10 N4y N 29.1200 -17.8500
11 C8x C 31.5700 -20.6500
12 C8x C 32.7600 -19.9500
13 C8y C 32.7600 -18.5500
14 C8x C 31.5700 -17.8500
15 C1b C 29.1200 -16.4500
16 C1b C 30.3100 -15.7500
17 C1b C 31.5000 -16.4500
18 N1y N 32.6900 -15.7500
19 C1x C 33.8800 -16.4500
20 C1x C 35.1400 -15.7500
21 N1y N 35.1400 -14.3500
22 C1x C 33.9500 -13.6500
23 C1x C 32.6900 -14.3500
24 C1b C 36.3300 -13.6500
25 C1b C 37.5200 -14.3500
26 O1a O 38.7100 -13.6500
27 X Cl 33.9500 -17.8500
BOND 30
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 8 11 2
13 11 12 1
14 12 13 2
15 13 14 1
16 9 14 2
17 10 15 1
18 15 16 1
19 16 17 1
20 17 18 1
21 18 19 1
22 19 20 1
23 20 21 1
24 21 22 1
25 22 23 1
26 18 23 1
27 21 24 1
28 24 25 1
29 25 26 1
30 13 27 1
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