KEGG   COMPOUND: C07666
Entry
C07666                      Compound                               
Name
Dapsone;
4,4'-Sulfonylbisbenzenamine;
Diaphenylsulfone
Formula
C12H12N2O2S
Exact mass
248.0619
Mol weight
248.3009
Structure
Remark
Same as: D00592
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D10 ANTI-ACNE PREPARATIONS
   D10A ANTI-ACNE PREPARATIONS FOR TOPICAL USE
    D10AX Other anti-acne preparations for topical use
     D10AX05 Dapsone
      D00592  Dapsone (USP) <JP/US>
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J04 ANTIMYCOBACTERIALS
   J04B DRUGS FOR TREATMENT OF LEPRA
    J04BA Drugs for treatment of lepra
     J04BA02 Dapsone
      D00592  Dapsone (USP) <JP/US>
USP drug classification [BR:br08302]
 Antimycobacterials
  Antimycobacterials, Other
   Dapsone
    D00592  Dapsone (USP)
 Dermatological Agents
  Topical Anti-infectives
   Antibacterials, dermatological
    Dapsone
     D00592  Dapsone (USP)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  26  Epidermides
   269  Miscellaneous
    2699  Others
     D00592  Dapsone (USP); Diaphenylsulfone (JAN)
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   623  Leprostatics
    6231  Sulfones
     D00592  Dapsone (USP); Diaphenylsulfone (JAN)
Drug groups [BR:br08330]
 Metabolizing enzyme substrate
  DG02855  CYP2E1 substrate
   D00592  Dapsone
  DG01633  CYP3A/CYP3A4 substrate
   DG02913  CYP3A4 substrate
    D00592  Dapsone
Antimicrobials [BR:br08307]
 Antibacterials
  Folic acid biosynthesis inhibitor
   Diaminodiphenyl sulfone
    D00592  Dapsone (USP) <JP/US>
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D00592
Pharmacogenomic biomarkers [br08341.html]
 Polymorphisms and mutations affecting drug response
  D00592
Prodrugs [br08324.html]
 D00592
Prodrugs [br08324.html]
 C07666
Other DBs
CAS: 80-08-0
PubChem: 9868
ChEBI: 4325
NIKKAJI: J4.247A
KCF data

ATOM        17
            1   S4a S    21.9800  -14.6136
            2   C8y C    23.1922  -15.3246
            3   C8y C    20.7736  -15.3187
            4   O3c O    20.9776  -13.6228
            5   O3c O    22.9708  -13.6228
            6   C8x C    24.4045  -14.6195
            7   C8x C    23.1922  -16.7234
            8   C8x C    19.5614  -14.6136
            9   C8x C    20.7736  -16.7175
            10  C8x C    25.6050  -15.3187
            11  C8x C    24.4045  -17.4168
            12  C8x C    18.3433  -15.3187
            13  C8x C    19.5614  -17.4168
            14  C8y C    25.6167  -16.7234
            15  C8y C    18.3433  -16.7175
            16  N1a N    26.8174  -17.4285
            17  N1a N    17.1369  -17.4168
BOND        18
            1     1   2 1
            2     1   3 1
            3     1   4 2
            4     1   5 2
            5     2   6 2
            6     2   7 1
            7     3   8 2
            8     3   9 1
            9     6  10 1
            10    7  11 2
            11    8  12 1
            12    9  13 2
            13   10  14 2
            14   12  15 2
            15   14  16 1
            16   15  17 1
            17   11  14 1
            18   13  15 1

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