KEGG   COMPOUND: C07868
Entry
C07868                      Compound                               
Name
Metoclopramide
Formula
C14H22ClN3O2
Exact mass
299.1401
Mol weight
299.7964
Structure
Remark
Same as: D00726
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
   A03F PROPULSIVES
    A03FA Propulsives
     A03FA01 Metoclopramide
      D00726  Metoclopramide (JP18/INN) <JP>
USP drug classification [BR:br08302]
 Antiemetics
  Antiemetics, Other
   Metoclopramide
    D00726  Metoclopramide (JP18/INN)
 Gastrointestinal Agents
  Gastrointestinal Agents, Other
   Metoclopramide
    D00726  Metoclopramide (JP18/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  23  Digestive organ agents
   239  Miscellaneous
    2399  Others
     D00726  Metoclopramide (JP18/INN)
Animal drugs in Japan [BR:br08331]
 93  Agents affecting digestive organs
  932  Antistomach, antidiarrhoics (including absorptives, antidiarrhoics, antibububble and preparations)
   9329  Other antistomach, antidiarrhoics and preparations
    C07868  Metoclopramide
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG01478  Dopamine antagonist
   DG01474  Dopamine D2-receptor antagonist
    DG00055  Metoclopramide
     D00726  Metoclopramide
 Gastrointestinal agent
  DG01763  Propulsive
   DG00055  Metoclopramide
    D00726  Metoclopramide
  DG01489  5-HT3-receptor antagonist
   DG00055  Metoclopramide
    D00726  Metoclopramide
  DG01762  Antiemetic
   DG01783  Benzamide type antiemetic
    DG00055  Metoclopramide
     D00726  Metoclopramide
 Metabolizing enzyme substrate
  DG01644  CYP2D6 substrate
   DG00055  Metoclopramide
    D00726  Metoclopramide
 Metabolizing enzyme inhibitor
  DG01645  CYP2D6 inhibitor
   DG00055  Metoclopramide
    D00726  Metoclopramide
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    DRD2
     D00726  Metoclopramide (JP18/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00726  Metoclopramide
  D00726  Metoclopramide tablets
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D00726
Other DBs
CAS: 364-62-5
PubChem: 10070
ChEBI: 107736
NIKKAJI: J2.037K
KCF data

ATOM        20
            1   C8y C    29.6159  -16.8048
            2   C8y C    29.6159  -15.4045
            3   C8x C    28.4256  -17.5050
            4   C5a C    30.8762  -17.5050
            5   C8x C    28.4256  -14.7044
            6   O2a O    30.8762  -14.7044
            7   C8y C    27.2355  -16.8048
            8   N1b N    32.0666  -16.8048
            9   O5a O    30.8762  -18.9053
            10  C8y C    27.2355  -15.4045
            11  C1a C    32.0666  -15.4045
            12  X   Cl   26.0452  -17.5050
            13  C1b C    33.3268  -17.5050
            14  N1a N    26.0452  -14.7044
            15  C1b C    34.5171  -16.8048
            16  N1c N    35.7074  -17.5050
            17  C1b C    36.9677  -16.8048
            18  C1b C    35.7074  -18.9053
            19  C1a C    38.1579  -17.5050
            20  C1a C    36.9677  -19.6054
BOND        20
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 2
            5     2   6 1
            6     3   7 1
            7     4   8 1
            8     4   9 2
            9     5  10 1
            10    6  11 1
            11    7  12 1
            12    8  13 1
            13   10  14 1
            14   13  15 1
            15   15  16 1
            16   16  17 1
            17   16  18 1
            18   17  19 1
            19   18  20 1
            20    7  10 2

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