KEGG   COMPOUND: C07952
Entry
C07952                      Compound                               
Name
Chlorpromazine hydrochloride;
Chloropromazine monohydrochloride
Formula
C17H19ClN2S. HCl
Exact mass
354.0724
Mol weight
355.3251
Structure
Remark
Same as: D00789
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05A ANTIPSYCHOTICS
    N05AA Phenothiazines with aliphatic side-chain
     N05AA01 Chlorpromazine
      D00789  Chlorpromazine hydrochloride (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
 Antiemetics
  Antiemetics, Other
   Chlorpromazine
    D00789  Chlorpromazine hydrochloride (JP18/USP)
 Antipsychotics
  1st Generation/Typical
   Chlorpromazine
    D00789  Chlorpromazine hydrochloride (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   117  Psychotropics
    1171  Chlorpromazines
     D00789  Chlorpromazine hydrochloride (JP18/USP)
Drug groups [BR:br08330]
 Cardiovascular agent
  DG01466  Adrenergic receptor antagonist
   DG01465  alpha-Adrenergic receptor antagonist
    DG01460  alpha2-Adrenergic receptor antagonist
     DG00867  Chlorpromazine
      D00789  Chlorpromazine hydrochloride
 Neuropsychiatric agent
  DG01478  Dopamine antagonist
   DG01474  Dopamine D2-receptor antagonist
    DG00867  Chlorpromazine
     D00789  Chlorpromazine hydrochloride
  DG01491  Muscarinic cholinergic receptor antagonist
   DG00867  Chlorpromazine
    D00789  Chlorpromazine hydrochloride
  DG03200  Antipsychotic agent
   DG01905  Phenothiazine antipsychotics
    DG00867  Chlorpromazine
     D00789  Chlorpromazine hydrochloride
 Anti-allergic agent
  DG01557  Histamine receptor antagonist
   DG01482  Histamine receptor H1 antagonist
    DG00867  Chlorpromazine
     D00789  Chlorpromazine hydrochloride
 Metabolizing enzyme substrate
  DG01644  CYP2D6 substrate
   DG00867  Chlorpromazine
    D00789  Chlorpromazine hydrochloride
 Metabolizing enzyme inhibitor
  DG01645  CYP2D6 inhibitor
   DG00867  Chlorpromazine
    D00789  Chlorpromazine hydrochloride
Drug classes [BR:br08332]
 Anti-allergic agent
  DG01482  Histamine receptor H1 antagonist
   D00789  Chlorpromazine hydrochloride
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    CHRM
     D00789  Chlorpromazine hydrochloride (JP18/USP) <JP/US>
   Adrenaline
    ADRA2
     D00789  Chlorpromazine hydrochloride (JP18/USP) <JP/US>
   Dopamine
    DRD2
     D00789  Chlorpromazine hydrochloride (JP18/USP) <JP/US>
   Histamine
    HRH1
     D00789  Chlorpromazine hydrochloride (JP18/USP) <JP/US>
   Serotonin
    HTR2
     D00789  Chlorpromazine hydrochloride (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00789  Chlorpromazine hydrochloride
  D00789  Chlorpromazine hydrochloride tablets
  D00789  Chlorpromazine hydrochloride injection
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D00789
Other DBs
CAS: 69-09-0
PubChem: 10153
ChEBI: 3649
NIKKAJI: J237.634B
KCF data

ATOM        22
            1   C8x C    21.4268  -17.0417
            2   C8x C    21.4268  -18.4443
            3   C8x C    22.6414  -19.1456
            4   C8y C    23.8562  -18.4443
            5   C8y C    23.8562  -17.0417
            6   C8x C    22.6414  -16.3404
            7   S2x S    25.0709  -19.1456
            8   C8y C    26.2856  -18.4443
            9   C8y C    26.2856  -17.0417
            10  N4y N    25.0709  -16.3404
            11  C8x C    27.5005  -19.1456
            12  C8x C    28.7151  -18.4443
            13  C8y C    28.7151  -17.0417
            14  C8x C    27.5005  -16.3404
            15  C1b C    25.0709  -14.9377
            16  C1b C    26.2877  -14.2352
            17  C1b C    27.4865  -14.9275
            18  N1c N    28.6756  -14.2410
            19  C1a C    29.8693  -14.9305
            20  C1a C    28.6758  -12.8340
            21  X   Cl   29.9339  -16.3381
            22  X   Cl   32.8304  -17.7102
BOND        23
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12    8  11 2
            13   11  12 1
            14   12  13 2
            15   13  14 1
            16    9  14 2
            17   10  15 1
            18   15  16 1
            19   16  17 1
            20   17  18 1
            21   18  19 1
            22   18  20 1
            23   13  21 1

» Japanese version

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Drug (1)   
   KEGG DRUG (1)   
Chemical substance (3)   
   PubChem (1)   
   ChEBI (1)   
   NIKKAJI (1)   
All databases (4)   

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