KEGG   COMPOUND: C08007
Entry
C08007                      Compound                               
Name
Buprenorphine
Formula
C29H41NO4
Exact mass
467.3036
Mol weight
467.6401
Structure
Remark
Same as: D07132
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N02 ANALGESICS
   N02A OPIOIDS
    N02AE Oripavine derivatives
     N02AE01 Buprenorphine
      D07132  Buprenorphine (JAN/INN) <JP/US>
  N07 OTHER NERVOUS SYSTEM DRUGS
   N07B DRUGS USED IN ADDICTIVE DISORDERS
    N07BC Drugs used in opioid dependence
     N07BC01 Buprenorphine
      D07132  Buprenorphine (JAN/INN) <JP/US>
USP drug classification [BR:br08302]
 Analgesics
  Opioid Analgesics, Long-acting
   Buprenorphine
    D07132  Buprenorphine (JAN/INN)
 Anti-Addiction/Substance Abuse Treatment Agents
  Opioid Dependence
   Buprenorphine
    D07132  Buprenorphine (JAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   114  Antipyretics and analgesics, anti-inflammatory agents
    1149  Others
     D07132  Buprenorphine (JAN/INN)
Drug groups [BR:br08330]
 Analgesic
  DG01984  Opioid analgesics
   DG00820  Buprenorphine
    D07132  Buprenorphine
  DG01586  Opioid receptor antagonist
   DG00820  Buprenorphine
    D07132  Buprenorphine
 Metabolizing enzyme substrate
  DG01633  CYP3A/CYP3A4 substrate
   DG02913  CYP3A4 substrate
    DG00820  Buprenorphine
     D07132  Buprenorphine
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Opioid
    OPRM1
     D07132  Buprenorphine (JAN/INN) <JP/US>
    OPRK1
     D07132  Buprenorphine (JAN/INN) <JP/US>
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D07132
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D07132
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D07132
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D07132
Narcotics and psychotropics in Japan [br08308.html]
 Psychotropics by Cabinet order Article 3 (78 substances)
  D07132
Other DBs
CAS: 52485-79-7
PubChem: 10207
ChEBI: 3216
NIKKAJI: J291.229E
KCF data

ATOM        34
            1   C1z C    20.6500  -21.7700
            2   C1z C    21.8400  -22.4700
            3   C1y C    19.4600  -22.4700
            4   C8y C    20.6500  -20.4400
            5   C1x C    21.8400  -21.0700
            6   C1y C    23.0300  -21.7700
            7   C1x C    21.8400  -23.8700
            8   C1x C    21.2800  -23.5200
            9   C1z C    19.4600  -23.8000
            10  O2x O    18.8300  -20.9300
            11  C8y C    19.5300  -19.7400
            12  C8y C    21.9100  -19.7400
            13  C1x C    24.2200  -21.0700
            14  N1y N    24.2200  -22.4700
            15  C1x C    23.1000  -20.4400
            16  C1y C    20.6500  -24.5000
            17  C1x C    20.0900  -22.8200
            18  C8y C    19.5300  -18.3400
            19  C8x C    21.9100  -18.3400
            20  C1b C    25.4100  -21.8400
            21  C8x C    20.7200  -17.6400
            22  O1a O    18.3400  -17.6400
            23  C1y C    26.6000  -22.5400
            24  C1x C    27.3000  -23.7300
            25  C1x C    28.0000  -22.5400
            26  O2a O    18.0600  -23.8000
            27  C1a C    17.3600  -22.6100
            28  C1d C    21.3500  -25.6900
            29  C1a C    22.7500  -25.6900
            30  C1d C    20.6500  -26.8800
            31  O1a O    22.0500  -26.8800
            32  C1a C    19.2500  -26.8800
            33  C1a C    21.3500  -28.0700
            34  C1a C    19.8100  -28.1400
BOND        40
            1     1   5 1 #Up
            2     2   6 1
            3     2   7 1
            4     2   8 1 #Down
            5     3   9 1
            6     3  10 1 #Down
            7     4  11 1
            8     4  12 2
            9     5  13 1
            10    6  14 1 #Up
            11    6  15 1
            12    7  16 1
            13    8  17 1
            14   11  18 2
            15   12  19 1
            16   14  20 1
            17   18  21 1
            18   18  22 1
            19    9  16 1
            20    9  17 1 #Down
            21   10  11 1
            22   12  15 1
            23   14  13 1 #Up
            24   19  21 2
            25    1   2 1
            26   20  23 1
            27    1   3 1
            28    1   4 1
            29   23  24 1
            30   23  25 1
            31   25  24 1
            32    9  26 1
            33   26  27 1
            34   16  28 1
            35   28  29 1 #Up
            36   28  30 1
            37   28  31 1 #Down
            38   30  32 1
            39   30  33 1
            40   30  34 1

» Japanese version

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Drug (1)   
   KEGG DRUG (1)   
Chemical substance (8)   
   PubChem (1)   
   ChEBI (1)   
   HMDB (1)   
   MASSBANK (4)   
   NIKKAJI (1)   
All databases (9)   

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