KEGG   COMPOUND: C08183
Entry
C08183                      Compound                               
Name
Triamcinolone acetonide
Formula
C24H31FO6
Exact mass
434.2105
Mol weight
434.4977
Structure
Remark
Same as: D00983
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A01 STOMATOLOGICAL PREPARATIONS
   A01A STOMATOLOGICAL PREPARATIONS
    A01AC Corticosteroids for local oral treatment
     A01AC01 Triamcinolone
      D00983  Triamcinolone acetonide (JP18/USP) <JP/US>
 C CARDIOVASCULAR SYSTEM
  C05 VASOPROTECTIVES
   C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
    C05AA Corticosteroids
     C05AA12 Triamcinolone
      D00983  Triamcinolone acetonide (JP18/USP) <JP/US>
 D DERMATOLOGICALS
  D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
   D07A CORTICOSTEROIDS, PLAIN
    D07AB Corticosteroids, moderately potent (group II)
     D07AB09 Triamcinolone
      D00983  Triamcinolone acetonide (JP18/USP) <JP/US>
   D07X CORTICOSTEROIDS, OTHER COMBINATIONS
    D07XB Corticosteroids, moderately potent, other combinations
     D07XB02 Triamcinolone
      D00983  Triamcinolone acetonide (JP18/USP) <JP/US>
 H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
  H02 CORTICOSTEROIDS FOR SYSTEMIC USE
   H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
    H02AB Glucocorticoids
     H02AB08 Triamcinolone
      D00983  Triamcinolone acetonide (JP18/USP) <JP/US>
 R RESPIRATORY SYSTEM
  R01 NASAL PREPARATIONS
   R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
    R01AD Corticosteroids
     R01AD11 Triamcinolone
      D00983  Triamcinolone acetonide (JP18/USP) <JP/US>
  R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
   R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
    R03BA Glucocorticoids
     R03BA06 Triamcinolone
      D00983  Triamcinolone acetonide (JP18/USP) <JP/US>
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01B ANTIINFLAMMATORY AGENTS
    S01BA Corticosteroids, plain
     S01BA05 Triamcinolone
      D00983  Triamcinolone acetonide (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
 Dental and Oral Agents
  Triamcinolone
   D00983  Triamcinolone acetonide (JP18/USP)
 Dermatological Agents
  Dermatitis and Pruitus Agents
   Glucocorticoids, Medium Potency
    Triamcinolone
     D00983  Triamcinolone acetonide (JP18/USP)
   Glucocorticoids, High Potency
    Triamcinolone
     D00983  Triamcinolone acetonide (JP18/USP)
 Hormonal Agents, Stimulant/Replacement/Modifying (Adrenal)
  Triamcinolone
   D00983  Triamcinolone acetonide (JP18/USP)
 Inflammatory Bowel Disease Agents
  Glucocorticoids
   Triamcinolone
    D00983  Triamcinolone acetonide (JP18/USP)
 Ophthalmic Agents
  Ophthalmic Anti-inflammatories
   Glucocorticoids, Ophthalmic
    Triamcinolone
     D00983  Triamcinolone acetonide (JP18/USP)
 Respiratory Tract/Pulmonary Agents
  Anti-inflammatories, Inhaled Corticosteroids
   Triamcinolone
    D00983  Triamcinolone acetonide (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  13  Agents affecting sensory organs
   131  Ophthalmic agents
    1319  Others
     D00983  Triamcinolone acetonide (JP18/USP)
 2  Agents affecting individual organs
  23  Digestive organ agents
   239  Miscellaneous
    2399  Others
     D00983  Triamcinolone acetonide (JP18/USP)
  24  Hormones
   245  Adrenal hormone preparations
    2454  Fluorinated adrenocorticotropic hormones
     D00983  Triamcinolone acetonide (JP18/USP)
  26  Epidermides
   264  Analgesics, anti-itchings, astringents, anti-inflammatory agents
    2646  Adrenocorticotropic hormones
     D00983  Triamcinolone acetonide (JP18/USP)
Classification of Japanese OTC drugs [BR:br08313]
 Agents for dental and stomatological use
  74 Stomatitis remedies
   D00983  Triamcinolone acetonide (JP18/USP)
Risk category of Japanese OTC drugs [BR:br08312]
 Designated second-class OTC drugs
  Inorganic and organic chemicals
   Triamcinolone acetonide
    D00983  Triamcinolone acetonide (JP18/USP)
 Second-class OTC drugs
  Inorganic and organic chemicals
   Triamcinolone acetonide
    D00983  Triamcinolone acetonide (JP18/USP)
Drug groups [BR:br08330]
 Anti-inflammatory
  DG01955  Corticosteroid
   DG02068  Glucocorticoid
    DG00010  Triamcinolone
     D00983  Triamcinolone acetonide
 Dermatological agent
  DG03243  Atopic dermatitis agent
   D00983  Triamcinolone acetonide
Drug classes [BR:br08332]
 Anti-inflammatory
  DG01955  Corticosteroid
   D00983  Triamcinolone acetonide
 Dermatological agent
  DG03243  Atopic dermatitis agent
   D00983  Triamcinolone acetonide
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Estrogen like receptors
   3-Ketosteroid receptor
    NR3C1 (GR)
     D00983  Triamcinolone acetonide (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00983  Triamcinolone acetonide
Topical steroids potency [br08317.html]
 Classification in the USA
  D00983
 Classification in Japan
  D00983
Rx-to-OTC switch list in the USA [br08315.html]
 D00983
Rx-to-OTC switch list in Japan [br08314.html]
 D00983
Other DBs
CAS: 76-25-5
PubChem: 10383
ChEBI: 71418
PDB-CCD: 1TA[PDBj]
NIKKAJI: J55.714E
KCF data

ATOM        31
            1   C2x C    18.6900  -29.1900
            2   C5x C    18.6900  -30.5200
            3   C2x C    19.8800  -31.2200
            4   C2y C    21.0700  -30.5200
            5   C1z C    21.0700  -29.1900
            6   C2x C    19.8800  -28.4900
            7   C1x C    22.2600  -31.2200
            8   C1x C    23.4500  -30.5200
            9   C1y C    23.4500  -29.1900
            10  C1z C    22.2600  -28.4900
            11  C1y C    24.5000  -28.4900
            12  C1z C    24.5000  -27.1600
            13  C1x C    23.4500  -26.4600
            14  C1y C    22.2600  -27.1600
            15  C1x C    26.8800  -28.4900
            16  C1y C    26.8800  -27.1600
            17  C1z C    25.6900  -26.4600
            18  O5x O    17.5700  -31.2200
            19  C1a C    21.0700  -27.7900
            20  X   F    22.2600  -29.8200
            21  O1a O    21.0700  -26.4600
            22  C1a C    24.5000  -25.7600
            23  C5a C    25.6900  -24.8500
            24  O2x O    27.0900  -25.5500
            25  O5a O    26.8800  -24.2200
            26  C1b C    24.5000  -24.2200
            27  O1a O    23.4500  -24.8500
            28  O2x O    28.2800  -27.1600
            29  C1z C    28.4900  -25.5500
            30  C1a C    29.8900  -25.5500
            31  C1a C    28.4900  -24.2200
BOND        35
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 2
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12    9  11 1
            13   11  12 1
            14   12  13 1
            15   13  14 1
            16   10  14 1
            17   11  15 1
            18   15  16 1
            19   16  17 1
            20   12  17 1
            21    2  18 2
            22    5  19 1 #Up
            23   10  20 1 #Down
            24   14  21 1 #Up
            25   12  22 1 #Up
            26   17  23 1 #Up
            27   17  24 1 #Down
            28   23  25 2
            29   23  26 1
            30   26  27 1
            31   16  28 1 #Down
            32   24  29 1
            33   29  28 1
            34   29  30 1
            35   29  31 1

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