KEGG   COMPOUND: C12888
Entry
C12888                      Compound                               
Name
Hydrocortisone succinate;
11beta,17,21-Trihydroxypregn-4-ene-3,20-dione 21-(hydrogensuccinate);
Cortisol succinate
Formula
C25H34O8
Exact mass
462.2254
Mol weight
462.5327
Structure
Remark
Same as: D01442
Brite
Lipids [BR:br08002]
 ST  Sterol lipids
  ST02 Steroids
   ST0203 C21 steroids (gluco/mineralocorticoids, progestogins) and derivatives
    C12888  Hydrocortisone succinate
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A01 STOMATOLOGICAL PREPARATIONS
   A01A STOMATOLOGICAL PREPARATIONS
    A01AC Corticosteroids for local oral treatment
     A01AC03 Hydrocortisone
      D01442  Hydrocortisone succinate (JP18)
  A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
   A07E INTESTINAL ANTIINFLAMMATORY AGENTS
    A07EA Corticosteroids acting locally
     A07EA02 Hydrocortisone
      D01442  Hydrocortisone succinate (JP18)
 C CARDIOVASCULAR SYSTEM
  C05 VASOPROTECTIVES
   C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
    C05AA Corticosteroids
     C05AA01 Hydrocortisone
      D01442  Hydrocortisone succinate (JP18)
 D DERMATOLOGICALS
  D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
   D07A CORTICOSTEROIDS, PLAIN
    D07AA Corticosteroids, weak (group I)
     D07AA02 Hydrocortisone
      D01442  Hydrocortisone succinate (JP18)
   D07X CORTICOSTEROIDS, OTHER COMBINATIONS
    D07XA Corticosteroids, weak, other combinations
     D07XA01 Hydrocortisone
      D01442  Hydrocortisone succinate (JP18)
 H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
  H02 CORTICOSTEROIDS FOR SYSTEMIC USE
   H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
    H02AB Glucocorticoids
     H02AB09 Hydrocortisone
      D01442  Hydrocortisone succinate (JP18)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01B ANTIINFLAMMATORY AGENTS
    S01BA Corticosteroids, plain
     S01BA02 Hydrocortisone
      D01442  Hydrocortisone succinate (JP18)
   S01C ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
    S01CB Corticosteroids/antiinfectives/mydriatics in combination
     S01CB03 Hydrocortisone
      D01442  Hydrocortisone succinate (JP18)
  S02 OTOLOGICALS
   S02B CORTICOSTEROIDS
    S02BA Corticosteroids
     S02BA01 Hydrocortisone
      D01442  Hydrocortisone succinate (JP18)
Drug groups [BR:br08330]
 Anti-inflammatory
  DG01955  Corticosteroid
   DG02068  Glucocorticoid
    DG00012  Hydrocortisone
     D01442  Hydrocortisone succinate
 Metabolizing enzyme substrate
  DG01633  CYP3A/CYP3A4 substrate
   DG00012  Hydrocortisone
    D01442  Hydrocortisone succinate
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Estrogen like receptors
   3-Ketosteroid receptor
    NR3C1 (GR)
     D01442  Hydrocortisone succinate (JP18)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01442  Hydrocortisone succinate
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D01442
Other DBs
CAS: 2203-97-6
PubChem: 583277
ChEBI: 31677
LIPIDMAPS: LMST02030126
3DMET: B04559
NIKKAJI: J7.358J
KCF data

ATOM        33
            1   C1y C    22.3789  -17.5209
            2   C1y C    21.1942  -18.2036
            3   C1z C    22.3789  -16.1552
            4   C1x C    24.7483  -17.5209
            5   C1y C    20.0095  -17.5209
            6   C1x C    21.1825  -19.5751
            7   C1z C    23.5695  -15.4666
            8   C1x C    21.1942  -15.4666
            9   C1a C    22.3731  -14.7837
            10  C1x C    24.7483  -16.1552
            11  C1z C    18.8191  -18.2036
            12  C1y C    20.0095  -16.1552
            13  C1x C    20.0095  -20.2578
            14  C5a C    23.5753  -14.1010
            15  O1a O    24.9118  -15.0931
            16  C2y C    18.8191  -19.5751
            17  C1x C    17.6401  -17.5209
            18  C1a C    18.8074  -16.8380
            19  O1a O    18.8191  -15.4666
            20  C1b C    24.7542  -13.4181
            21  O5a O    22.3848  -13.4181
            22  C2x C    17.6401  -20.2578
            23  C1x C    16.4497  -18.2036
            24  O7a O    25.9447  -14.1067
            25  C5x C    16.4497  -19.5751
            26  O5x O    15.2650  -20.2578
            27  C7a C    27.1454  -13.4076
            28  C1b C    28.3513  -14.0988
            29  C1b C    29.5571  -13.4007
            30  C6a C    30.7630  -14.0917
            31  O6a O    27.1407  -12.0114
            32  O6a O    30.7674  -15.4879
            33  O6a O    31.9699  -13.3897
BOND        36
            1     3   8 1
            2     3   9 1 #Up
            3     4  10 1
            4     5  11 1
            5     5  12 1
            6     6  13 1
            7     7  14 1 #Up
            8     7  15 1 #Down
            9    11  16 1
            10   11  17 1
            11   11  18 1 #Up
            12   12  19 1 #Up
            13   14  20 1
            14   14  21 2
            15   16  22 2
            16   17  23 1
            17   20  24 1
            18   22  25 1
            19   25  26 2
            20    7  10 1
            21    8  12 1
            22   13  16 1
            23   23  25 1
            24   24  27 1
            25    1   2 1
            26   27  28 1
            27    1   3 1
            28   28  29 1
            29    1   4 1
            30   29  30 1
            31    2   5 1
            32   27  31 2
            33    2   6 1
            34   30  32 2
            35    3   7 1
            36   30  33 1

» Japanese version

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Drug (1)   
   KEGG DRUG (1)   
Chemical substance (5)   
   PubChem (1)   
   ChEBI (1)   
   3DMET (1)   
   LIPIDMAPS (1)   
   NIKKAJI (1)   
All databases (6)   

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